Results 101 to 110 of about 31,656 (310)

A comparison of the microarchitecture of lower limb long bones between some animal models and humans: a review

open access: yesVeterinární Medicína, 2013
Animal models are unavoidable and indispensable research tools in the fields of bone tissue engineering and experimental orthopaedics. The fact that there is not ideal animal model as well as the differences in the bone microarchitecture and physiology ...
V.J. Cvetkovic   +6 more
doaj   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

open access: yesAdvanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng   +9 more
wiley   +1 more source

Redefining Crystalline Silicon: Unlocking New Horizons in Transparent and Flexible Photovoltaics

open access: yesAdvanced Energy Materials, EarlyView.
Crystalline silicon is presented as a platform for transparent and flexible photovoltaics. This review article outlines design principles for optical strategies to fabricate transparent silicon solar cells, mechanical strategies that mitigate silicon brittleness, and emerging concepts such as singlet‐fission spectral conversion and tandem architectures,
Kangmin Lee
wiley   +1 more source

Microarchitecture for defect tolerance and resiliency

open access: yes, 2007
Continued device scaling allows faster and more complex CPUs but comes at the cost of an increase in the likelihood of CPU failures. This thesis address this worsening problem at the architectural level; proposing and evaluating three microarchitectures ...
Schuchman, Ethan
core  

Macrophage-Driven Biomaterial Degradation Depends on Scaffold Microarchitecture

open access: yesFrontiers in Bioengineering and Biotechnology, 2019
In situ tissue engineering is a technology in which non-cellular biomaterial scaffolds are implanted in order to induce local regeneration of replaced or damaged tissues.
Tamar B. Wissing   +12 more
doaj   +1 more source

Deep Learning‐Assisted Design of Mechanical Metamaterials

open access: yesAdvanced Intelligent Discovery, EarlyView.
This review examines the role of data‐driven deep learning methodologies in advancing mechanical metamaterial design, focusing on the specific methodologies, applications, challenges, and outlooks of this field. Mechanical metamaterials (MMs), characterized by their extraordinary mechanical behaviors derived from architected microstructures, have ...
Zisheng Zong   +5 more
wiley   +1 more source

Microcomputed tomography of the femur of diabetic rats: alterations of trabecular and cortical bone microarchitecture and vasculature—a feasibility study

open access: yesEuropean Radiology Experimental, 2019
Background To better understand bone fragility in type 2 diabetes mellitus and define the contribution of microcomputed tomography (micro-CT) to the evaluation of bone microarchitecture and vascularisation, we conducted an in vitro preliminary study on ...
David Zeitoun   +5 more
doaj   +1 more source

FGF23 and bone microarchitecture [PDF]

open access: yesOsteoporosis International, 2019
T, Rupp, M, Amling, T, Rolvien
openaire   +2 more sources

A Computational Approach for Biomimetic Design of Liver‐On‐A‐Chip

open access: yesAdvanced Intelligent Discovery, EarlyView.
A biomimetic liver‐on‐a‐chip with antiparallel perfusion was designed using COMSOL‐guided simulation to replicate hepatic acinus transport. Full‐scale modelling revealed diffusion‐dominated, length‐dependent nutrient gradients and low‐shear conditions.
Zhenxu Yang   +9 more
wiley   +1 more source

AI‐BioMech: Deep Learning Prediction of Mechanical Behavior in Aperiodic Biological Cellular Materials

open access: yesAdvanced Intelligent Discovery, EarlyView.
AI‐BioMech is a deep learning framework that predicts the mechanical behavior of biological cellular materials directly from 2D images. By replacing traditional finite element analysis with semantic segmentation, it identifies stress and strain distributions with 99% accuracy, offering a high‐speed, scalable alternative for analyzing complex, aperiodic
Haleema Sadia   +2 more
wiley   +1 more source

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