Results 91 to 100 of about 907,938 (379)
The genesis of microarrays [PDF]
Biochemistry and Molecular Biology Education, 2013 AbstractThis review provides a perspective on the initial development of microarray technologies by two independent groups in the late 1980s. © 2013 by The International Union of Biochemistry and Molecular Biology, 42(2):106–113, 2014.
Pirrung, Michael C, Southern, Edwin M
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Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam +6 more
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Transcriptome analysis of rice root responses to potassium deficiency
BMC Plant Biology, 2012 Background Potassium (K+) is an important nutrient ion in plant cells and plays crucial roles in many plant physiological and developmental processes.
Ma Tian-Li, Wu Wei-Hua, Wang Yi
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Инфекция и иммунитет, 2020 A total of 399 Neisseria gonorrhoeae clinical isolates collected in different regions of the Russian Federation in 20152017 were analyzed for tetracycline susceptibility and genetic markers of resistance.
E. I. Dementieva +7 more
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Microarraying for Mechanosensivitity [PDF]
Cell Stem Cell, 2010 In a recent issue of Science, Gilbert et al. combine biomaterial microarrays with lineage tracking to demonstrate that muscle stem cell survival is sensitive to the microenvironment's mechanical stiffness (Gilbert et al., 2010). This work enhances the breadth and depth of knowledge in stem cell mechanobiology.
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PROTEOMICS – Clinical Applications, 2009 AbstractLectin microarray is a new technology that utilizes a panel of lectins immobilized on well‐defined substrate for high‐throughout analysis of glycans and glycoproteins. In this article, we have reviewed the fabrication and detection schemes in lectin microarray and discussed its novel applications in glycomics. We have also demonstrated a lectin
Shen, Hu, David T, Wong
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Mitofusin 2 (MFN2) is a major causative gene for axonal Charcot – Marie – Tooth disease type 2A (CMT2A), with a wide phenotypic spectrum. Comprehensive large ‐ scale genotype – phenotype association studies are essential for understanding disease pathogenesis and improved clinical management.
Masahiro Ando +13 more
wiley +1 more source
Differential Expression of MicroRNAs in Leprosy Skin Lesions
Frontiers in Immunology, 2017 Leprosy, a chronic infectious disease caused by Mycobacterium leprae, is a major public health problem in poor and developing countries of the Americas, Africa, and Asia.
Cleverson T. Soares +12 more
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B mu G@Sbase - a microarray database and analysis tool [PDF]
, 2002 The manufacture and use of a whole-genome microarray is a complex process and it is essential that all data surrounding the process is stored, is accessible and can be easily associated with the data generated following hybridization and scanning.
Hinds, J, Witney, AA
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Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou +12 more
wiley +1 more source