Results 71 to 80 of about 493,696 (293)

Identification of Potential Diagnostic and Prognostic Biomarkers for Gastric Cancer Based on Bioinformatic Analysis

Frontiers in Genetics, 2022
Background: Gastric cancer (GC) is one of the most prevalent cancers all over the world. The molecular mechanisms of GC remain unclear and not well understood. GC cases are majorly diagnosed at the late stage, resulting in a poor prognosis.
Xiaoji Niu, Xiaoji Niu, Liman Ren, Aiyan Hu, Shuhui Zhang, Hongjun Qi   +5 more
doaj   +1 more source

Information visualization for DNA microarray data analysis: A critical review [PDF]

, 2008
Graphical representation may provide effective means of making sense of the complexity and sheer volume of data produced by DNA microarray experiments that monitor the expression patterns of thousands of genes simultaneously.
Kuljis, J, Liu, X, Zhang, Leishi, Zhang, L, Kujis, J.N., Liu, Xiaohui   +5 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Construction and evaluation of a whole genome microarray of Chlamydomonas reinhardtii [PDF]

, 2011
Toepel J, Albaum S, Arvidsson S, et al. Construction and evaluation of a whole genome microarray of Chlamydomonas reinhardtii. BMC Genomics. 2011;12(1): 579.ABSTRACT: BACKGROUND: Chlamydomonas reinhardtii is widely accepted as a model organism regarding ...
La Russa, Marco, Goesmann, Alexander ; https://orcid.org/, Arvidsson, S., Toepel, Jörg, Goesmann, A., Samuel Arvidsson, La Russa, M., Marco la Russa, Kristin Rogge, Toepel Jörg, Rogge Kristin, Alexander Goesmann, Albaum, Stefan ; https://orcid.org/, Kruse, Olaf ; https://orcid.org/, Olaf Kruse, Jörg Toepel, Arvidsson Samuel, Rogge, K., Goesmann Alexander, Albaum Stefan P, Toepel, J., Stefan P Albaum, Kruse Olaf, la Russa Marco, Albaum, S., Rogge, Kristin, Kruse, O.   +26 more
core   +2 more sources

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

A description of the origins, design and performance of the TRAITS-SGP Atlantic salmon Salmo salar L. cDNA microarray [PDF]

, 2008
The origins, design, fabrication and performance of an Atlantic salmon microarray are described. The microarray comprises 16 950 Atlantic salmon-derived cDNA features, printed in duplicate and mostly sourced from pre-existing expressed sequence tag (EST)
Carmichael, S. N., Carmichael, Stephen N, Teale, Alan J, C. J. Secombes (7674242), Tocher, D. R., Bron, James, Seear, P J, R. Talbot (7674227), Talbot, R, Martin, S. A. M., Villeneuve, L A N, Martin, S A M, Teale, A J, Seear, Paul J, Bron, J. E., Villeneuve, L. A. N., Sweeney, G E, Tocher, D R, D. R. Tocher (7674245), J. E. Bron (3151167), Seear, P. J., S. A. Martin (2499343), S. N. Carmichael (7674230), Høyheim, B., Paul J. Seear (3360119), Villeneuve, Laure, Martin, Sam A M, A. J. Teale (7674248), Secombes, C J, Secombes, C. J., Taggart, J. B., Tocher, Douglas R, Taggart, John, Høyheim, B, Carmichael, S N, Sweeney, Glen E., Sweeney, Glen E, Secombes, Christopher J, Hoyheim, Bjorn, L. A. Villeneuve (7674233), Houlihan, Dominic F, Bron, J E, Houlihan, D. F., B. Høyheim (7674224), J. B. Taggart (7674221), D. F. Houlihan (7674239), Taggart, J B, Talbot, R., G. E. Sweeney (7674236), Talbot, Richard T, Houlihan, D F, Teale, A. J.   +51 more
core   +1 more source

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra, Nagendra K. Rai, Timothy D. Niepokny, Haley Courtney, Ajai Tripathi, Ranjan Dutta   +5 more
wiley   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

A temporal precedence based clustering method for gene expression microarray data [PDF]

, 2010
Background: Time-course microarray experiments can produce useful data which can help in understanding the underlying dynamics of the system. Clustering is an important stage in microarray data analysis where the data is grouped together according to ...
Li Chang-Tsun, Buchanan-Wollaston, Vicky, Chang-Tsun Li, Vicky Buchanan-Wollaston, Krishna, Ritesh V., Ritesh Krishna, Buchanan-Wollaston Vicky, Krishna Ritesh, Li, Chang-Tsun   +8 more
core   +1 more source