Results 51 to 60 of about 493,696 (293)
Identification of Messenger RNA Signatures in Age-Dependent Renal Impairment
Diagnostics, 2023 In general populations, age-dependent renal impairment contributes to the progression of renal dysfunction. It has not been known which molecules are involved in age-dependent renal impairment.
Katsunori Yanai +5 more
doaj +1 more source
A software framework for microarray and gene expression object model (MAGE-OM) array design annotation [PDF]
, 2008 Background The MIAME and MAGE-OM standards defined by the MGED society provide a specification and implementation of a software infrastructure to facilitate the submission and sharing of data from microarray studies via public repositories.
Ivens Alasdair +6 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Annals of Medicine, 2023 Background Rheumatoid arthritis (RA) is a chronic autoimmune disease associated with an increased risk of death, but its underlying mechanisms are not fully understood.
Li Xue +19 more
doaj +1 more source
Analytical Cellular Pathology, 2007 The use of high throughput genetic and expression platforms are generating many candidate diagnostic markers and therapeutic targets for a wide variety of clinical conditions. Tissue microarrays can be used for the evaluation of the utility of many of these markers.
J. Korbelik +4 more
openaire +3 more sources
PLS dimension reduction for classification of microarray data [PDF]
, 2004 PLS dimension reduction is known to give good prediction accuracy in the context of classification with high-dimensional microarray data. In this paper, PLS is compared with some of the best state-of-the-art classification methods.
Boulesteix, Anne-Laure
core +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Microarray image processing: A novel neural network framework [PDF]
, 2011 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Due to the vast success of bioengineering techniques, a series of large-scale analysis tools has been developed to discover the functional organization of ...
Zineddin, Bachar
core +6 more sources
SOD3 improves the tumor response to chemotherapy by stabilizing endothelial HIF-2α
Nature Communications, 2018 Tumour vasculature influences drug delivery. Here, the authors show that SOD3 re-expression enhances doxorubicin delivery and effects through normalization of tumour vasculature via the HIF-2a/VE-cadherin pathway.
Emilia Mira +15 more
doaj +1 more source
A Pathway Analysis Tool for Analyzing Microarray Data of Species with Low Physiological Information [PDF]
, 2008 Pathway information provides insight into the biological processes underlying microarray data. Pathway information is widely available for humans and laboratory animals in databases through the internet, but less for other species, for example, livestock.
Pas, M.F.W., te +13 more
core +1 more source