Results 41 to 50 of about 350,087 (166)
SOD3 improves the tumor response to chemotherapy by stabilizing endothelial HIF-2α
Nature Communications, 2018 Tumour vasculature influences drug delivery. Here, the authors show that SOD3 re-expression enhances doxorubicin delivery and effects through normalization of tumour vasculature via the HIF-2a/VE-cadherin pathway.
Emilia Mira +15 more
doaj +1 more source
Frontiers in Genetics, 2022 Background: Gastric cancer (GC) is one of the most prevalent cancers all over the world. The molecular mechanisms of GC remain unclear and not well understood. GC cases are majorly diagnosed at the late stage, resulting in a poor prognosis.
Xiaoji Niu +5 more
doaj +1 more source
Analytical Cellular Pathology, 2007 The use of high throughput genetic and expression platforms are generating many candidate diagnostic markers and therapeutic targets for a wide variety of clinical conditions. Tissue microarrays can be used for the evaluation of the utility of many of these markers.
J. Korbelik +4 more
openaire +3 more sources
, 2009 Protein microarrays containing nearly the entire yeast proteome have been constructed. They are typically prepared by overexpression and high-throughput purification and printing onto microscope slides. The arrays can be used to screen nearly the entire proteome in an unbiased fashion and have enormous utility for a variety of applications.
Fasolo, Joseph, Snyder, Michael
openaire +2 more sources
Characterisation of PVL-Positive Staphylococcus argenteus from the United Arab Emirates
AntibioticsStaphylococcus argenteus is a recently described staphylococcal species that is related to Staphylococcus aureus but lacks the staphyloxanthin operon. It is able to acquire both resistance markers such as the SCCmec elements and mobile genetic elements ...
Stefan Monecke +10 more
doaj +1 more source
Multiple Chromoanasynthesis in a Rare Case of Sporadic Renal Leiomyosarcoma: A Case Report
Frontiers in Oncology, 2020 We present the genetic profile of kidney giant leiomyosarcoma characterized by sequencing of 409 cancer related genes and chromosomal microarray analysis.
Kirill Igorevich Anoshkin +12 more
doaj +1 more source
Analysis of Gene Expression Profile of AGS Cells Stimulated by Helicobacter pylori Adhesion
Gut and Liver, 2007 Background/Aims: Interactions between H. pylori and gastric epithelial cells contribute to gastric inflam-mation and epithelial damage. This study was performed to evaluate the gene expression profile of AGS cells by adhesion of H. pylori.
doaj +1 more source
Asian Pacific Journal of Tropical BiomedicineObjective: To identify promising biomarkers for the pathogenesis of major depressive disorder (MDD). Methods: Microarray chips of MDD patients, including the GSE98793, GSE52790, and GSE39653 datasets, were obtained from the Gene Expression Omnibus ...
Ying Zeng +5 more
doaj +1 more source
Microarraying for Mechanosensivitity [PDF]
Cell Stem Cell, 2010 In a recent issue of Science, Gilbert et al. combine biomaterial microarrays with lineage tracking to demonstrate that muscle stem cell survival is sensitive to the microenvironment's mechanical stiffness (Gilbert et al., 2010). This work enhances the breadth and depth of knowledge in stem cell mechanobiology.
openaire +2 more sources
Identification of Potential Therapeutic Targets Against Anthrax-Toxin-Induced Liver and Heart Damage
ToxinsAnthrax represents a disease resulting from infection by toxin-secreting bacteria, Bacillus anthracis. This research aimed to identify new therapeutic targets to combat anthrax.
Lihong Wu +10 more
doaj +1 more source