Results 21 to 30 of about 883,556 (350)

Information visualization for DNA microarray data analysis: A critical review [PDF]

open access: yes, 2008
Graphical representation may provide effective means of making sense of the complexity and sheer volume of data produced by DNA microarray experiments that monitor the expression patterns of thousands of genes simultaneously.
Kuljis, J, Liu, X, Zhang, L
core   +1 more source

Omega-3 fatty acid intake suppresses induction of diverse autoantibody repertoire by crystalline silica in lupus-prone mice

open access: yesAutoimmunity, 2020
Inhalation of crystalline silica (cSiO2) in the workplace is etiologically linked to lupus and other autoimmune diseases. Exposing lupus-prone NZBWF1 mice to respirable cSiO2 unleashes a vicious cycle of inflammation and cell death in the lung that ...
Lichchavi D. Rajasinghe   +9 more
doaj   +1 more source

Plasma Cell-Free DNA Methylomics of Bipolar Disorder With and Without Rapid Cycling

open access: yesFrontiers in Neuroscience, 2021
Rapid cycling (RC) burdens bipolar disorder (BD) patients further by causing more severe disability and increased suicidality. Because diagnosing RC can be challenging, RC patients are at risk of rapid decline due to delayed suitable treatment.
Ada Man-Choi Ho   +9 more
doaj   +1 more source

Gene Expression Meta-Analysis identifies Cytokine Pathways and 5q Aberrations involved in Metastasis of ERBB2 Amplified and Basal Breast Cancer

open access: yesCancer Informatics, 2013
Background Breast tumors have been described by molecular subtypes characterized by pervasively different gene expression profiles. The subtypes are associated with different clinical parameters and origin of precursor cells.
Mads Thomassen   +3 more
doaj   +1 more source

Replication Study: Transcriptional amplification in tumor cells with elevated c-Myc

open access: yeseLife, 2018
As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Blum et al., 2015), that described how we intended to replicate selected experiments from the paper ‘Transcriptional amplification in tumor cells with elevated c ...
L Michelle Lewis   +6 more
doaj   +1 more source

Microarray Identifies a Key Carcinogenic Circular RNA 0008594 That Is Related to Non-Small-Cell Lung Cancer Development and Lymph Node Metastasis and Promotes NSCLC Progression by Regulating the miR-760-Mediated PI3K/AKT and MEK/ERK Pathways

open access: yesFrontiers in Oncology, 2021
PurposeThis study aimed to explore the circular RNA (circRNA/circ) profile engaged in non-small cell lung cancer (NSCLC) development and metastasis and to investigate potentially key carcinogenic circRNAs related to NSCLC.MethodsCircRNA profiles between ...
Qiushi Wang   +8 more
doaj   +1 more source

Predictive analysis of microarray data [PDF]

open access: yes, 2014
Microarray gene expression data are analyzed by means of a Bayesian nonparametric model, with emphasis on prediction of future observables, yielding a method for selection of differentially expressed genes and a ...
F., Paulo C. Marques   +1 more
core   +1 more source

Minimum Information About a Microarray Experiment (MIAME) – Successes, Failures, Challenges

open access: yesThe Scientific World Journal, 2009
The Minimum Information About a Microarray Experiment (known as MIAME) guidelines describe information that needs to be provided to enable the interpretation of the results of a microarray-based experiment unambiguously.
Alvis Brazma
doaj   +1 more source

Seasonal dynamics of DNA and RNA viral bioaerosol communities in a daycare center

open access: yesMicrobiome, 2019
Background Viruses play an important role in ecosystems, including the built environment (BE). While numerous studies have characterized bacterial and fungal microbiomes in the BE, few have focused on the viral microbiome (virome).
Aaron J. Prussin   +6 more
doaj   +1 more source

Influence of the Postmortem/Storage Time of Human Corneas on the Properties of Cultured Limbal Epithelial Cells

open access: yesCells, 2022
Besides being a powerful model to study the mechanisms of corneal wound healing, tissue-engineered human corneas (hTECs) are sparking interest as suitable substitutes for grafting purposes. To ensure the histological and physiological integrity of hTECs,
Gaëtan Le-Bel   +6 more
doaj   +1 more source

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