Results 21 to 30 of about 350,087 (166)

Replication Study: Transcriptional amplification in tumor cells with elevated c-Myc

open access: yeseLife, 2018
As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Blum et al., 2015), that described how we intended to replicate selected experiments from the paper ‘Transcriptional amplification in tumor cells with elevated c ...
L Michelle Lewis   +6 more
doaj   +1 more source

An Omnibus Test for Differential Distribution Analysis of Continuous Microbiome Data

open access: yesIEEE Access, 2021
The human microbiome is comprised of thousands of microbial species. These species will substantially influence the normal physiology of humans and cause numerous diseases. Microbiome data can be measured by sequencing, microarray, or other technologies.
Xiang Lin   +3 more
doaj   +1 more source

Minimum Information About a Microarray Experiment (MIAME) – Successes, Failures, Challenges

open access: yesThe Scientific World Journal, 2009
The Minimum Information About a Microarray Experiment (known as MIAME) guidelines describe information that needs to be provided to enable the interpretation of the results of a microarray-based experiment unambiguously.
Alvis Brazma
doaj   +1 more source

Seasonal dynamics of DNA and RNA viral bioaerosol communities in a daycare center

open access: yesMicrobiome, 2019
Background Viruses play an important role in ecosystems, including the built environment (BE). While numerous studies have characterized bacterial and fungal microbiomes in the BE, few have focused on the viral microbiome (virome).
Aaron J. Prussin   +6 more
doaj   +1 more source

Transcriptional changes in the rat brain induced by repetitive transcranial magnetic stimulation

open access: yesFrontiers in Human Neuroscience, 2023
IntroductionTranscranial Magnetic Stimulation (TMS) is a noninvasive technique that uses pulsed magnetic fields to affect the physiology of the brain and central nervous system.
Marina Weiler   +12 more
doaj   +1 more source

Microarray Data Analysis: From Hypotheses to Conclusions Using Gene Expression Data

open access: yesCellular Oncology, 2004
We review several commonly used methods for the design and analysis of microarray data. To begin with, some experimental design issues are addressed.
Nicola J. Armstrong, Mark A. van de Wiel
doaj   +1 more source

Transcriptome changes associated with elongation of bovine conceptuses II: Differentially expressed transcripts in the endometrium on day 17 after insemination

open access: yesJournal of Dairy Science, 2023
: The objective was to characterize endometrial transcriptome on d 17 of gestation in dairy cows according to conceptus length. Nonlactating Holstein cows (n = 48) were slaughtered 17 d after AI and the uterine horn ipsilateral to the corpus luteum (CL ...
P.M. Peixoto   +5 more
doaj   +1 more source

Combining bioinformatics and machine learning to identify common mechanisms and biomarkers of chronic obstructive pulmonary disease and atrial fibrillation

open access: yesFrontiers in Cardiovascular Medicine, 2023
BackgroundPatients with chronic obstructive pulmonary disease (COPD) often present with atrial fibrillation (AF), but the common pathophysiological mechanisms between the two are unclear.
Ziyi Sun   +11 more
doaj   +1 more source

Ensifer meliloti L6-AK89, an Effective Inoculant of Medicago lupulina Varieties: Phenotypic and Deep-Genome Screening

open access: yesAgronomy, 2022
This paper presents a deep analysis of the accessory genome of an economically promising strain of Ensifer (Sinorhizobium) meliloti, L6-AK89, obtained as a result of next-generation high-throughput sequencing (MiSeq, MinIon).
Marina L. Roumiantseva   +7 more
doaj   +1 more source

Registered report: Transcriptional amplification in tumor cells with elevated c-Myc

open access: yeseLife, 2015
The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012.
David Blum   +3 more
doaj   +1 more source

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