Results 11 to 20 of about 493,696 (293)
Towards data grids for microarray expression profiles [PDF]
The UK DTI funded Biomedical Research Informatics Delivered by Grid Enabled Services (BRIDGES) project developed a Grid infrastructure through which research into the genetic causes of hypertension could be supported by scientists within the large ...
Bayliss, C., Sinnott, R.O.
core +5 more sources
New high-throughput screening technologies have led to the identification of hundreds of genes with potential roles in cancer or other diseases. For evaluation of promising candidate genes, however, in-situ analysis of high numbers of clinical tissue samples is mandatory. The tissue microarray (TMA) technology greatly facilitates such analysis. In this
Simon R, Mirlacher M, Sauter G
openaire +10 more sources
Security-oriented data grids for microarray expression profiles [PDF]
Microarray experiments are one of the key ways in which gene activity can be identified and measured thereby shedding light and understanding for example on biological processes. The BBSRC funded Grid enabled Microarray Expression Profile Search (GEMEPS)
Bayliss, C., Jiang, J., Sinnott, R.O.
core +5 more sources
Abstract Microarrays are revolutionizing genetics by making it possible to genotype hundreds of thousands of DNA markers and to assess the expression (RNA transcripts) of all of the genes in the genome. Microarrays are slides the size of a postage stamp that contain millions of DNA sequences to which singleāstranded DNA or RNA can hybridize.
Plomin, Robert, Schalkwyk, Leonard C
openaire +4 more sources
Microarray sub-grid detection: A novel algorithm [PDF]
This is the post print version of the article. The official published version can be obtained from the link below - Copyright 2007 Taylor & Francis LtdA novel algorithm for detecting microarray subgrids is proposed. The only input to the algorithm is the
Liu, X, Wang, Z, Morris, D
core +1 more source
Surface free energy and microarray deposition technology [PDF]
Microarray techniques use a combinatorial approach to assess complex biochemical interactions. The fundamental goal is simultaneous, large-scale experimentation analogous to the automation achieved in the semiconductor industry.
Glen Mchale, McHale, Glen, McHale, G
core +1 more source
Development and validation of a bovine macrophage specific cDNA microarray [PDF]
Background The response of macrophages to danger signals is an important early stage in the immune response. Our understanding of this complex event has been furthered by microarray analysis, which allows the simultaneous investigation of the expression ...
Waddington David +14 more
core +1 more source
Microarrays are simple assays that measure the relative expression levels of tens of thousands of genes. Excitement about their importance and potential contributions to biology and medicine has been intense. Nonetheless, recent insights into the limitations and pitfalls of microarrays have led to caution about data interpretation. Microarrays are very
openaire +4 more sources
Sperm associated antigen 9 (SPAG9) a promising therapeutic target of ovarian carcinoma
SPAG9 is a novel tumor associated antigen, expressed in variety of malignancies. However, its role in ovarian cancer remains unexplored. SPAG9 expression was validated in ovarian cancer cells by real time PCR and Western blot.
Nirmala Jagadish +6 more
doaj +1 more source
Plasma Cell-Free DNA Methylomics of Bipolar Disorder With and Without Rapid Cycling
Rapid cycling (RC) burdens bipolar disorder (BD) patients further by causing more severe disability and increased suicidality. Because diagnosing RC can be challenging, RC patients are at risk of rapid decline due to delayed suitable treatment.
Ada Man-Choi Ho +9 more
doaj +1 more source

