Results 161 to 170 of about 695,874 (306)

Sensitivity Issues in DNA Array-Based Expression Measurements and Performance of Nylon Microarrays for Small Samples

, 1999
François Bertucci, Karine Bernard, Béatrice Loriod, Yuan‐Chih Chang, Samuel Granjeaud, Daniel Birnbaum, Catherine Nguyen, Konan Peck, B.R. Jordan   +8 more
openalex   +1 more source

Knowledge-based analysis of microarray gene expression data by using support vector machines [PDF]

, 2000
Michael P. Brown, William Noble Grundy, David Lin, Nello Cristianini, Charles W. Sugnet, Terrence S. Furey, Manuel Ares, David Haussler   +7 more
openalex   +1 more source

SMC4 Promotes Prostate Cancer Cell Proliferation and Metastasis via the Rheb/mTOR Pathway

Advanced Science, EarlyView.
Structural maintenance of chromosome protein 4 (SMC4) has been implicated in prostate cancer metastasis. Knockdown of SMC4 in RM1‐LM cells significantly attenuates proliferation, migration, and lung metastasis in vivo. Furthermore, SMC4 interacts with GLUT1 (Slc2a1), thereby enhancing glycolysis, ATP production, and activation of the Rheb/mTOR pathway.
Wei Zhang, Siyuan Qin, Xiaokang Li, Ming Chang, Tianzi Wei, Xin Huang, Haibo Tong, Xia Guo, Yi Lu, Jian Zhang   +9 more
wiley   +1 more source

Identification of eukaryotic mRNAs that are translated at reduced cap binding complex eIF4F concentrations using a cDNA microarray

, 1999
Gregg J. Johannes, Mark S. Carter, Michael B. Eisen, Patrick O. Brown, Peter Sarnow   +4 more
openalex   +1 more source

Importance of replication in microarray gene expression studies: Statistical methods and evidence from repetitive cDNA hybridizations [PDF]

, 2000
Mei‐Ling Ting Lee, Frank C. Kuo, G. À. Whitmore, Jeffrey Sklar   +3 more
openalex   +1 more source

Dual Role of CRABP2 in Colorectal Cancer: Oncogenesis via Nuclear RB1 and Cytoplasmic AFG3L2/SLC25A39 Axis, While Limiting Liver Metastasis through Cytoplasmic AFG3L2/PINK1/Parkin‐Mediated Mitophagy

Advanced Science, EarlyView.
CRABP2 plays a dual role in colorectal cancer: it promotes proliferation and suppresses apoptosis through the nuclear CRABP2/RB1 axis and the cytoplasmic AFG3L2/SLC25A39 axis. Meanwhile, it inhibits colorectal liver metastasis via AFG3L2/PINK1/Parkin‐mediated mitophagy.
Chuanxin Tian, Sheng Yang, Chuan Zhang, Renzhong Zhu, Chen Chen, Xiaowei Wang, Dongsheng Zhang, Qingyang Sun, Hengjie Xu, Hongxu Nie, Yue Zhang, Dongjian Ji, Junwei Tang, Kangpeng Jin, Yueming Sun   +14 more
wiley   +1 more source

Comprehensive Identification of Cell Cycle–regulated Genes of the YeastSaccharomyces cerevisiaeby Microarray Hybridization

, 1998
Paul T. Spellman, Gavin Sherlock, Michael Q. Zhang, Vishwanath R. Iyer, Kirk R. Anders, Michael B. Eisen, Patrick O. Brown, David Botstein, Bruce Futcher   +8 more
openalex   +2 more sources

Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray [PDF]

, 2000
Tetsuya S. Tanaka, Saied A. Jaradat, Meng K. Lim, George J. Kargul, Xiaohong Wang, Marija J. Grahovac, Serafino Pantano, Yuri Sano, Yulan Piao, Ramaiah Nagaraja, Hirofumi Doi, William H. Wood, Kevin G. Becker, Minoru S.H. Ko   +13 more
openalex   +1 more source

Efficient Generation of Megakaryocyte Progenitors and Platelets From HSPCs via JAK2/STAT3 Signaling

Advanced Science, EarlyView.
This research presents a novel strategy employing the VGM cocktail, which combines HES7 overexpression with HDAC inhibitor and GABA, to enhance platelet production from hematopoietic stem and progenitor cells by promoting megakaryocyte progenitor (MkP) generation.
Huicong Liu, Lingna Wang, Jiaqing Liu, Haitao Yuan, Kaiqing Zhang, Yun Qiu, Fangfang Zhu   +6 more
wiley   +1 more source

Support vector machine classification and validation of cancer tissue samples using microarray expression data [PDF]

, 2000
Terrence S. Furey, Nello Cristianini, Nigel Duffy, David Bednarski, Michèl Schummer, David Haussler   +5 more
openalex   +1 more source