Results 181 to 190 of about 883,556 (350)

lumi: a pipeline for processing Illumina microarray

open access: yesBioinform., 2008
Pan Du, W. Kibbe, Simon M. Lin
semanticscholar   +1 more source

PRMT5/Sohlh2/Sirt1 Signaling Pathway in Vascular Endothelial Cells Modulates Lung Metastasis of Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
The cover image shows that vascular endothelial cells play an important role in lung metastasis of TNBC. Endothelial Sohlh2 acts as a gatekeeper against TNBC lung metastasis by limiting endothelial activation and tumor cell passage. PRMT5 reduces Sohlh2 stability, weakening this protective barrier.
Ruihong Zhang   +8 more
wiley   +1 more source

Knowledge-based analysis of microarray gene expression data by using support vector machines.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2000
M. S. Brown   +7 more
semanticscholar   +1 more source

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li   +13 more
wiley   +1 more source

Inhibition of Focal Adhesion Restricts Chemoresistance in Pancreatic Cancer by Targeting SLC7A11 Mediated Ferroptosis

open access: yesAdvanced Science, EarlyView.
FAK signaling drives chemoresistance and tumor evolution in pancreatic ductal adenocarcinoma. The FAK inhibitor IN10018 restores gemcitabine sensitivity by inducing SLC7A11‐mediated ferroptosis through the PI3K‐Akt pathway and remodeling the tumor microenvironment, reducing mesenchymal components while enhancing CD8+ T‐cell infiltration in preclinical ...
Yingjin Wang   +11 more
wiley   +1 more source

Chorionic Villi Sampling among Early and Late Gestational Age: Does Timing Affect Yield and Outcomes? [PDF]

open access: yesAJP Rep
Kim J   +11 more
europepmc   +1 more source

Normalization of cDNA microarray data.

open access: yesMethods, 2003
G. Smyth, T. Speed
semanticscholar   +1 more source

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