Results 211 to 220 of about 902,749 (382)

Transcriptomic analysis at 48 h postmortem: a proof of concept for the identification of biomarkers to estimate time since death. [PDF]

Mol Biol Rep
Zepeta Flores N, Garduño Zarazúa LM, Piñón Zarate G, Cárdenas Monroy CA, Mercado Salomon A, Pérez Zamora O, Pedraza Lara C, Millán Catalán O, Rosas Vargas H, Jiménez Morales S, Pérez Plasencia C, Guardado Estrada M.   +11 more
europepmc   +1 more source

A NONPARAMETRIC SCORING ALGORITHM FOR IDENTIFYING INFORMATIVE GENES FROM MICROARRAY DATA [PDF]

, 2000
Peter J. Park, Marcello Pagano, Marco Bonetti   +2 more
openalex   +1 more source

Deacetylation of ACLY Mediates RNA M6A‐Modification of NOXA and Promotes Chemoresistance of Colorectal Cancer

Advanced Science, EarlyView.
This study investigates the deacetylation of ACLY at K978 acts as a novel risk in colorectal cancer chemoresistance. The deacetylation of K978 induces ACLY relocation to the nucleus and promotes its binding to RBM15, a m6A methylation modification “writer”.
Jun Wen, Mengqin Shen, Haitao Zhao, Liu Liu, Qian Hua, Xiaoping Zhao, Jianjun Liu, Haizhong Feng, Gang Huang   +8 more
wiley   +1 more source

Expression of Concern: Atm inhibition decreases lens opacity in a rat model of galactose-induced cataract. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

m6A‐Modified circRAPGEF1 Interaction with IGF2BP3 Promotes Hepatocellular Carcinoma Progression via Reprogramming Aspartate Metabolism

Advanced Science, EarlyView.
In hepatocellular carcinoma (HCC), the m6A‐modified circRAPGEF1 destabilizes ASS1 mRNA via competitive binding to IGF2BP3, driving aspartate metabolic reprogramming in liver cancer stem cells (LCSCs). This cascade enhances stemness properties and reduces sorafenib sensitivity in LCSCs, thereby identifying circRAPGEF1 as a promising therapeutic target ...
Juanyi Shi, Sintim Mui, Yongcong Yan, Shaomin Liu, Kai Wen, Chuanchao He, Huoming Li, Hao Liao, Meng Tao, Jiahua Wen, Weidong Wang, Xiaoding Xu, Zhenyu Zhou, Zhiyu Xiao   +13 more
wiley   +1 more source

Expression of concern: Analysis of cataract-regulated genes using chemical DNA damage induction in a rat ex vivo model. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

The Gene Expression Profile of Human Umbilical Vein Endothelial Cells Stimulated by Tumor Necrosis Factor a Using DNA Microarray Analysis

, 2000
Takeshi Murakami, Chikage Mataki, Chizuru Nagao, Michihisa Umetani, Y Wada, Masami Ishii, Shuichi Tsutsumi, Takahide Kohro, Akio Saiura, Hiroyuki Aburatani, Takao Hamakubo, Tatsuhiko Kodama   +11 more
openalex   +2 more sources

The microarray revolution [PDF]

Nature Reviews Genetics, 2007
openaire   +1 more source

Single‐Cell Transcriptomics Reveals ITGA2‐Mediated Metabolic Reprogramming and Immune Crosstalk in Pediatric Thyroid Carcinogenesis

Advanced Science, EarlyView.
This study unveils ITGA2⁺ tumor cells as key drivers of pediatric thyroid cancer aggressiveness. These cells orchestrate dual oncogenic pathways: GLUT1‐mediated glycolytic reprogramming and M2 macrophage polarization. This metabolic‐immunological crosstalk promotes tumor progression and metastasis.
Zhi‐jun Zhan, Ning Li, Yan Sun, Lu Chen, Jun‐da Yin, Yun‐han Shan, Jia‐xing Zeng, Zhe‐cheng Li, Hai‐long Tan, Neng Tang, Shi Chang, Peng Huang   +11 more
wiley   +1 more source

Expression of Concern: HIF-1 inhibition reverses opacity in a rat model of galactose-induced cataract. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source