Results 81 to 90 of about 544,008 (293)

SMYD3 Promotes Immune Evasion in Clear Cell Renal Cell Carcinoma via SREBP1‐Mediated Transactivation of CD47

Advanced Science, EarlyView.
Cancer cell‐intrinsic SMYD3 orchestrates an immunosuppressive microenvironment and impairs the response to PD‐1 blockade by reprogramming immune cells landscape in the tumor microenvironment of clear cell renal cell carcinoma (ccRCC). The immunomodulatory function of SMYD3 is mediated via the SREBP1/CD47 pathway.
Zhengfang Liu, Xiumei Zhao, Maolin Zang, Huiyang Yuan, Xin Qin, Xiaofeng Li, Shuo Zhao, Ruirong Tan, Keqiang Yan, Li Liu, Yidong Fan, Ning Zhang, Benkang Shi, Bo Han, Shouzhen Chen   +14 more
wiley   +1 more source

ST6GAL1‐Mediated Sialylation Stabilizes PD‐L1 and Drives Immunosuppressive Tumor Microenvironment in Colorectal Cancer

Advanced Science, EarlyView.
ST6GAL1 plays a critical role in tumor progression and immune regulation in colorectal cancer (CRC). Its depletion significantly suppresses the malignant phenotype of CRC cells and enhances the efficacy of anti‐PD‐L1 therapy. High ST6GAL1 expression promotes an immune‐activated tumor microenvironment (TME), characterized by increased infiltration of ...
Ximo Xu, Jingyi Liu, Wei Qin, Chengsheng Ding, Zhenghao Cai, Duohuo Shu, Hao Zhong, Yanyan Hu, Mengqin Yu, Leqi Zhou, Jianwen Li, Minhua Zheng, Bin Li, Sen Zhang, Xiao Yang, Bo Feng   +15 more
wiley   +1 more source

Java Treeview - extensible visualization of microarray data

Bioinform., 2004
A. Saldanha
semanticscholar   +1 more source

Sensitivity Issues in DNA Array-Based Expression Measurements and Performance of Nylon Microarrays for Small Samples

, 1999
François Bertucci, Karine Bernard, Béatrice Loriod, Yuan‐Chih Chang, Samuel Granjeaud, Daniel Birnbaum, Catherine Nguyen, Konan Peck, B.R. Jordan   +8 more
openalex   +1 more source

Topoisomerase I Inhibition in ETV4‐overexpressed Non‐Small Cell Lung Cancer Promotes Replication and Transcription Mediated R‐Loop Accumulation and DNA Damage

Advanced Science, EarlyView.
The oncogenic ETS factor ETV4 exerts a pleiotropic control over DNA replication both in a transcription‐dependent and ‐independent fashion in NSCLC cells. High‐ETV4 expression leads to R‐loop formation and DNA damage in response to TOP1 inhibition.
Jiaxi Zhang, Yan Wang, Shanhu Cao, Shelly M. Xie, Bei Liu, Yimeng Li, Yuqi Hou, Xue Meng, Mingzhu Ruan, Di Bu, Jia Kang, Ruxin Li, Lei Lou, Juan Wang, Lingxiao Xing   +14 more
wiley   +1 more source

Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation.

Nucleic Acids Research, 2002
Y. H. Yang, S. Dudoit, Percy Luu, Dave Lin, V. Peng, J. Ngai, T. Speed   +6 more
semanticscholar   +1 more source

PCR Amplification on a Microarray of Gel-Immobilized Oligonucleotides: Detection of Bacterial Toxin- and Drug-Resistant Genes and Their Mutations [PDF]

, 2000
Boris N. Strizhkov, Alexei L. Drobyshev, V. M. Mikhailovich, A.D. Mirzabekov   +3 more
openalex   +1 more source

Unraveling the Role of MDK‐SDC4 Interaction in Pancreatic Cancer‐Associated New‐Onset Diabetes by Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
Midkine (MDK) is a mediator of the interaction between pancreatic cancer and beta cells. MDK, which originated from pancreatic ductal adenocarcinoma cells, exerted deleterious effects on paraneoplastic beta cells by binding to the SDC4 receptor on the beta cell surface and subsequently downregulating the Ras signaling pathway, thereby impairing insulin
Zengyu Feng, Jianyao Lou, Chuanshuai Lin, Haocheng Yu, Yuheng Tu, Jiali Gong, Xiawei Li, Yulian Wu   +7 more
wiley   +1 more source

Minimum information about a microarray experiment (MIAME)—toward standards for microarray data

Nature Genetics, 2001
A. Brazma, P. Hingamp, John Quackenbush, G. Sherlock, P. Spellman, C. Stoeckert, John D Aach, W. Ansorge, C. Ball, Helen C. Causton, T. Gaasterland, Patrick Glenisson, F. Holstege, Irene F. Kim, V. Markowitz, J. Matese, H. Parkinson, A. Robinson, Ugis Sarkans, S. Schulze-Kremer, Jason E. Stewart, Ronald C. Taylor, J. Vilo, M. Vingron   +23 more
semanticscholar   +1 more source

Protein Microarrays [PDF]

BioTechniques, 2006
Chien-Sheng Chen, Heng Zhu
openaire   +3 more sources