Results 81 to 90 of about 724,095 (330)

Over-Expression of OsHOX24 Confers Enhanced Susceptibility to Abiotic Stresses in Transgenic Rice via Modulating Stress-Responsive Gene Expression

Frontiers in Plant Science, 2017
Homeobox transcription factors play critical roles in plant development and abiotic stress responses. In the present study, we raised rice transgenics over-expressing stress-responsive OsHOX24 gene (rice homeodomain-leucine zipper I sub-family member ...
Mukesh Jain, Mukesh Jain, Annapurna Bhattacharjee, Raghvendra Sharma   +3 more
doaj   +1 more source

Effects of Flight on Gene Expression and Aging in the Honey Bee Brain and Flight Muscle [PDF]

, 2012
Honey bees move through a series of in-hive tasks (e.g., “nursing”) to outside tasks (e.g., “foraging”) that are coincident with physiological changes and higher levels of metabolic activity.
Ammons, Andrew, Benito, Azucena A., Elekonich, Michelle M., Mancinelli, Georgina E., Margotta, Joseph, Roberts, Stephen P.   +5 more
core   +5 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Predictors of primary breast cancers responsiveness to preoperative Epirubicin/Cyclophosphamide-based chemotherapy: translation of microarray data into clinically useful predictive signatures

Journal of Translational Medicine, 2005
Background Our goal was to identify gene signatures predictive of response to preoperative systemic chemotherapy (PST) with epirubicin/cyclophosphamide (EC) in patients with primary breast cancer.
Munnes Marc, Prisack Hans-Bernd, Modlich Olga, Audretsch Werner, Bojar Hans   +4 more
doaj   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Transcriptome analysis of rice root responses to potassium deficiency

BMC Plant Biology, 2012
Background Potassium (K+) is an important nutrient ion in plant cells and plays crucial roles in many plant physiological and developmental processes.
Ma Tian-Li, Wu Wei-Hua, Wang Yi
doaj   +1 more source

Biological microchip for assessing tetracycline-resistance in Neisseria gonorrhoeae clinical isolates in Russian Federation

Инфекция и иммунитет, 2020
A total of 399 Neisseria gonorrhoeae clinical isolates collected in different regions of the Russian Federation in 20152017 were analyzed for tetracycline susceptibility and genetic markers of resistance.
E. I. Dementieva, B. L. Shaskolskiy, A. T. Leinsoo, D. A. Gryadunov, N. P. Petrova, A. V. Chestkov, A. A. Kubanov, D. G. Deryabin   +7 more
doaj   +1 more source

Optical Genome Mapping And Single Nucleotide Polymorphism Microarray: An Integrated Approach For Investigating Challenging Cases Of Products Of Conception [PDF]

, 2022
Nikhil Sahajpal, Ashis K. Mondal, Sudha Ananth, Chetan Pundkar, Kimya Jones, Colin Williams, Timothy Fee, Amanda Weissman, Giuseppe Daniele Tripodi, Eesha Oza, Larisa Gavrilova‐Jordan, Nivin Omar, Alex Hastie, Barbara R. DuPont, Lawrence C. Layman, Alka Chaubey, Ravindra Kolhe   +16 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Differential Expression of MicroRNAs in Leprosy Skin Lesions

Frontiers in Immunology, 2017
Leprosy, a chronic infectious disease caused by Mycobacterium leprae, is a major public health problem in poor and developing countries of the Americas, Africa, and Asia.
Cleverson T. Soares, Ana P. F. Trombone, Luciana R. V. Fachin, Patricia S. Rosa, Cássio C. Ghidella, Rodrigo F. Ramalho, Mabel G. Pinilla, Mabel G. Pinilla, Alex F. Carvalho, Alex F. Carvalho, Dirce N. Carrara, Fernando A. Soares, Andrea F. F. Belone   +12 more
doaj   +1 more source