Results 211 to 220 of about 19,288,705 (257)

Glycan microarray analysis of <i>Candida</i>-related antibodies in human and mice sera guides biomarker discovery and vaccine development. [PDF]

Proc Natl Acad Sci U S A
Reuber EE, Hickey E, Pradhan A, Sprute R, Lingscheid T, Tober-Lau P, Leaves I, Stappers MHT, Kurth F, Bruno M, Netea MG, Sander LE, Cornely OA, Gow NAR, Brown AJP, Singh RK, Omoregbee-Leichnitz S, Sletten ET, Danglad-Flores J, Seeberger PH.   +19 more
europepmc   +1 more source

Ac‐SDKP modulates apoptosis via HSP27 and the FAS/FASL and mitochondrial axes

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of Ac‐SDKP regulating the FAS/FASL and mitochondrial apoptosis pathways via HSP27. Ac‐SDKP inhibits HSP27 expression, activates the FAS/FASL pathway and Caspase‐3 signaling, increases Caspase‐8 and Caspase‐3 expression, and induces cell apoptosis.
Wenxin Guo, Jinyin Yan, Wenli Li, Jin Wang, Lu Liu, Chengmei Zhang, Wei Cao, Shanshan Yao, Haibo Gong, Yi He, Zihan Zhou, Siyan Chen, Li Feng, Haijing Deng   +13 more
wiley   +1 more source

A Synthetic β‐Mannan Epitope Enables Immunization and Detection of Candida auris

Angewandte Chemie, EarlyView.
A synthetic β‐mannan epitope enables both active and passive immunization against Candida auris. Conjugation to the carrier protein CRM197 induces protective antibody responses, while monoclonal antibodies targeting the same epitope support detection using a lateral flow assay, linking glycochemistry with antifungal prevention and diagnostics ...
Emelie E. Reuber, Arnab Pradhan, Ian Leaves, Rajat K. Singh, Emer Hickey, Carola Geiler, Neil A. R. Gow, Alistair J. P. Brown, Peter H. Seeberger   +8 more
wiley   +2 more sources

A Prospective Evaluation of the Diagnostic Utility for Low-Coverage Genome Sequencing in Prenatal Samples: A Comparison With Chromosomal Microarray Analysis. [PDF]

Prenat Diagn
Yin Y, He Y, Chen C, He Y, Wang J, Qin S, Wang H, Ma K, Hu D, Xiao R, Wang G, Wang X.   +11 more
europepmc   +1 more source

Gephyrin Neurological Autoimmunity

Annals of Neurology, EarlyView.
Gephyrin is a postsynaptic scaffold protein essential for inhibitory neurotransmission. Gephyrin‐immunoglobulin G (IgG) was reported, decades ago, in a single case of paraneoplastic stiff‐person‐like syndrome, but its broader clinical relevance remains unknown.
Maria Chiara Pantuliano, Friederike A. Arlt, Naomi Arenson, Irena Dujmovic Basuroski, Divyanshu Dubey, Connie E. Lesnick, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael A. Lane, Andrew McKeon   +10 more
wiley   +1 more source

Unveiling biomarker detection in Alzheimer's disease: a computational approach to microarray analysis. [PDF]

3 Biotech
Khan NS, Choudhary S, Ali M, Shawaz M, Lohnes BJ, Poddar NK.   +5 more
europepmc   +1 more source

Identification of senescence-related biomarkers for osteoporosis based on microarray analysis, Mendelian randomization, and experimental validation. [PDF]

Mamm Genome
Zhu Y, Zhao J, Li Z, Chen Y.
europepmc   +1 more source

Chromosomal Microarray Analysis in Fetuses with Ultrasound Abnormalities. [PDF]

Int J Gen Med
Chen X, Lan L, Wu H, Zeng M, Zheng Z, Zhong Q, Lai F, Hu Y.   +7 more
europepmc   +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

Angewandte Chemie International Edition, EarlyView.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

Microarray Analysis Reveals Sepsis Is a Syndrome with Hyperactivity of TH17 Immunity, with Over-Presentation of the Treg Cell Cytokine TGF-β. [PDF]

Curr Issues Mol Biol
Chen YJ, Lu JJ, Lin CP, Hu WC.
europepmc   +1 more source