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Utility of whole exome sequencing in the evaluation of isolated fetal growth restriction in normal chromosomal microarray analysis. [PDF]
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GeneMCL in microarray analysis
Computational Biology and Chemistry, 2005Accurately and reliably identifying the actual number of clusters present with a dataset of gene expression profiles, when no additional information on cluster structure is available, is a problem addressed by few algorithms. GeneMCL transforms microarray analysis data into a graph consisting of nodes connected by edges, where the nodes represent genes,
B. Samuel Lattimore +2 more
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Methods, 2003
We describe detailed protocols and results with an integrated platform for studying relative transcript expression, including microarray design and fabrication, analysis and calibration algorithms, and high throughput quantitative real-time PCR. This approach optimizes sensitivity and accuracy while controlling the cost of experiments.
Elisa, Wurmbach +2 more
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We describe detailed protocols and results with an integrated platform for studying relative transcript expression, including microarray design and fabrication, analysis and calibration algorithms, and high throughput quantitative real-time PCR. This approach optimizes sensitivity and accuracy while controlling the cost of experiments.
Elisa, Wurmbach +2 more
openaire +2 more sources
2007
Microarrays and related technologies have allowed investigators to ask biological questions in far greater detail than has previously been possible. Microarrays had a troubled beginning, but most of these problems resulted from the growing pains of this technology, which, like many new things, was initially more promise than delivery.
Grier P, Page +5 more
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Microarrays and related technologies have allowed investigators to ask biological questions in far greater detail than has previously been possible. Microarrays had a troubled beginning, but most of these problems resulted from the growing pains of this technology, which, like many new things, was initially more promise than delivery.
Grier P, Page +5 more
openaire +2 more sources
Comparative Microarray Analysis
OMICS: A Journal of Integrative Biology, 2006Microarrays enable high-throughput parallel gene expression analysis, and their use has grown exponentially during the past decade. We are now in a position where individual experiments could benefit from using the swelling public data repositories to allow microarrays to progress from being a hypothesis-generating tool to a powerful resource that can ...
Ola, Larsson +2 more
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Microarray Analysis of Hypertension
2017Hypertension is a complex disorder in which multiple genes, pathways, and organ systems simultaneously interact to contribute to the final level of blood pressure. Fully elucidating these interactions is an important area of hypertension research and one in which high-throughput methods such as microarrays can play a key role.
Henry L, Keen, Curt D, Sigmund
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Nature Medicine, 2003
Microarrays permit the analysis of gene expression, DNA sequence variation, protein levels, tissues, cells and other biological and chemical molecules in a massively parallel format. Robust microarray manufacture, hybridization, detection and data analysis technologies permit novice users to adapt this exciting technology readily, and more experienced ...
Robin L, Stears +2 more
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Microarrays permit the analysis of gene expression, DNA sequence variation, protein levels, tissues, cells and other biological and chemical molecules in a massively parallel format. Robust microarray manufacture, hybridization, detection and data analysis technologies permit novice users to adapt this exciting technology readily, and more experienced ...
Robin L, Stears +2 more
openaire +2 more sources
2010
Gene expression profiling has revolutionized functional genomics research by providing a quick handle on all the transcriptional changes that occur in the cell in response to internal or external perturbations or developmental programs. Microarrays have become the most popular technology for recording gene expression profiles.
Saroj K, Mohapatra, Arjun, Krishnan
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Gene expression profiling has revolutionized functional genomics research by providing a quick handle on all the transcriptional changes that occur in the cell in response to internal or external perturbations or developmental programs. Microarrays have become the most popular technology for recording gene expression profiles.
Saroj K, Mohapatra, Arjun, Krishnan
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Microarray Analysis of Sarcomas
Advances in Anatomic Pathology, 2006Microarrays began to be used to study gene expression profiles in the mid-1990s, but it was only after 2000 that serious attempts have been made to apply this technology to investigate sarcomas. Microarray technologies provide a comprehensive survey of active molecular pathways and potential molecular targets for diagnosis and treatment, but are ...
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