Results 31 to 40 of about 23,313,531 (341)

Data-Driven Analysis of Age, Sex, and Tissue Effects on Gene Expression Variability in Alzheimer's Disease

Frontiers in Neuroscience, 2019
Alzheimer's disease (AD) has been categorized by the Centers for Disease Control and Prevention (CDC) as the 6th leading cause of death in the United States.
Lavida R. K. Brooks, George I. Mias
doaj   +1 more source

Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis

BMC Bioinformatics, 2010
BackgroundHigh-throughput profiling of DNA methylation status of CpG islands is crucial to understand the epigenetic regulation of genes. The microarray-based Infinium methylation assay by Illumina is one platform for low-cost high-throughput methylation
Pan Du, Xiao Zhang, Chiang-Ching Huang, N. Jafari, W. Kibbe, L. Hou, Simon M. Lin   +6 more
semanticscholar   +1 more source

The Potential of 2-aza-8-Oxohypoxanthine as a Cosmetic Ingredient

Cosmetics, 2021
In this study, we verified the effects of 2-aza-8-oxohypoxanthine (AOH) on human epidermal cell proliferation by performing DNA microarray analysis. Cell proliferation was assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide ...
Hisae Aoshima, Masayuki Ito, Rinta Ibuki, Hirokazu Kawagishi   +3 more
doaj   +1 more source

Effects of glucose metabolism on the regulation of genes of fatty acid synthesis and triglyceride secretion in the livers⃞

Journal of Lipid Research, 2007
Glucose disposal induces a signal that modulates the transcriptional regulation of genes involved in the glycolysis and lipogenesis pathways. To investigate the role of glucose metabolism on hepatic gene expression independently from insulin action, we ...
Núria Morral, Howard J. Edenberg, Scott R. Witting, Jennifer Altomonte, Tearina Chu, Matthew Brown   +5 more
doaj   +1 more source

Methylation Analysis by Microarray [PDF]

, 2009
Differential methylation hybridization (DMH) is a high-throughput DNA methylation screening tool that utilizes methylation-sensitive restriction enzymes to profile methylated fragments by hybridizing them to a CpG island microarray. This array contains probes spanning all the 27,800 islands annotated in the UCSC Genome Browser. Herein we describe a DMH
Daniel E, Deatherage, Dustin, Potter, Pearlly S, Yan, Tim H-M, Huang, Shili, Lin   +4 more
openaire   +2 more sources

Detection of changes in gene regulatory patterns, elicited by perturbations of the Hsp90 molecular chaperone complex, by visualizing multiple experiments with an animation

BioData Mining, 2011
Background To make sense out of gene expression profiles, such analyses must be pushed beyond the mere listing of affected genes. For example, if a group of genes persistently display similar changes in expression levels under particular experimental ...
Echeverría Pablo C, Forafonov Fedor, Pandey Deo P, Mühlebach Guillaume, Picard Didier   +4 more
doaj   +1 more source

Evaluating the green credentials and performance of deep eutectic solvents in the extraction of antibiotics and mycotoxins in foods

Green Chemistry Letters and Reviews
Deep eutectic solvents (DES) are new generation solvents that have recently emerged as a sustainable alternative to organic solvents in the extraction of chemical contaminants in foods.
Oluwatobi Kolawole, Chongdee Thammakhet-Buranachai, Awanwee Petchkongkaew, Thanasat Sooksimuang, Christopher Elliott, Nitsara Karoonuthaisiri   +5 more
doaj   +1 more source

Global transcriptional response of oral squamous cell carcinoma cell lines to health-associated oral bacteria - an in vitro study

Journal of Oral Microbiology, 2022
Background We have recently demonstrated that health-associated oral bacteria Streptococcus mitis, Neisseria flavescens, and Haemophilus parainfluenzae induce cytotoxicity in oral squamous cell carcinoma (OSCC) cell lines and downregulate CD36, a cancer ...
Divyashri Baraniya, Kumaraswamy Naidu Chitrala, Nezar Noor Al-Hebshi   +2 more
doaj   +1 more source

Changing paradigms of anti-VEGF in the Indian scenario

Indian Journal of Ophthalmology, 2014
Anti-vascular endothelial growth factors (VEGF) agents have revolutionized the treatment of retinal diseases. Use of anti-VEGF agents in the Indian Scenario present some unique challenges considering the absence of compounding pharmacies, poor penetrance
P Mahesh Shanmugam
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source