Results 21 to 30 of about 23,939,903 (293)

Defining quantification methods and optimizing protocols for microarray hybridization of circulating microRNAs

Scientific Reports, 2017
MicroRNAs (miRNAs) have emerged as promising biomarkers of disease. Their potential use in clinical practice requires standardized protocols with very low miRNA concentrations, particularly in plasma samples.
Anna Garcia-Elias, Leonor Alloza, Eulàlia Puigdecanet, Lara Nonell, Marta Tajes, Joao Curado, Cristina Enjuanes, Oscar Díaz, Jordi Bruguera, Julio Martí-Almor, Josep Comín-Colet, Begoña Benito   +11 more
doaj   +1 more source

Molecular Pathogenesis and Immune Evasion of Vesicular Stomatitis New Jersey Virus Inferred from Genes Expression Changes in Infected Porcine Macrophages

Pathogens, 2021
The molecular mechanisms associated with the pathogenesis of vesicular stomatitis virus (VSV) in livestock remain poorly understood. Several studies have highlighted the relevant role of macrophages in controlling the systemic dissemination of VSV during
Lauro Velazquez-Salinas, Jessica A. Canter, James J. Zhu, Luis L. Rodriguez   +3 more
doaj   +1 more source

Analysing Microarray Data using the Multi-functional Immune Ontologiser

Journal of Integrative Bioinformatics, 2006
Gene expression microarrays are a prominent experimental tool in functional genomics allowing researchers to gain a deeper understanding of biological processes.
Khalid Sabah, Khan Mohsin, Wang Ping, Liu Xiaohui, Li Suling   +4 more
doaj   +1 more source

CIDA: An integrated software for the design, characterisation and global comparison of microarrays

Journal of Integrative Bioinformatics, 2007
Microarray technology has had a significant impact in the field of systems biology involving the investigation into the biological systems that regulate human life. Identifying genes of significant interest within any given disease on an individual basis
Khalid Sabah, Khan Mohsin, Symonds Alistair, Fraser Karl, Wang Ping, Liu Xiaohui, Li Suling   +6 more
doaj   +1 more source

Differential Gene Sets Profiling in Gram-Negative and Gram-Positive Sepsis

Frontiers in Cellular and Infection Microbiology, 2022
BackgroundThe host response to bacterial sepsis is reported to be nonspecific regardless of the causative pathogen. However, newer paradigms indicated that the host response of Gram-negative sepsis may be different from Gram-positive sepsis, and the ...
Qingliang Wang, Xiaojie Li, Wenting Tang, Xiaoling Guan, Zhiyong Xiong, Yong Zhu, Jiao Gong, Bo Hu   +7 more
doaj   +1 more source

Genomic Microarray Analysis [PDF]

, 2015
Microarrays utilize classical hybridization techniques to measure the levels of expression of genomic sequences. Advances in microarray fabrication using robotic technology and bioinformatics, now means entire genomes can be interrogated with a high degree of sensitivity, specificity and throughput.
Hamlet, S, Petcu, E, Ivanovski, S
openaire   +3 more sources

Microarray Expression Profiles of lncRNAs and mRNAs in Postoperative Cognitive Dysfunction

Frontiers in Neuroscience, 2018
Postoperative cognitive dysfunction (POCD) is serious disorder in the central nervous system common in aged patients after anesthesia. Although its clinical symptoms are well recognized, however, the molecular etiology of the POCD remains unrevealed ...
Ying Zhang, Yue-Xin Liu, Qiu-Xia Xiao, Qing Liu, Rui Deng, Jiang Bian, Isaac Bul Deng, Mohammed Al-Hawwas, Feng-Xu Yu   +8 more
doaj   +1 more source

Chronic Stress-Induced Gene Changes In Vitro and In Vivo: Potential Biomarkers Associated With Depression and Cancer Based on circRNA- and lncRNA-Associated ceRNA Networks

Frontiers in Oncology, 2021
Circular RNAs (circRNAs) and long noncoding RNAs (lncRNAs) have been considered as biomarkers or regulators in many diseases. However, the exact role of circRNA- or lncRNA-mediated competing endogenous RNA (ceRNA) networks in the modulation of depression
Ting Zhou, Ting Zhou, Mingming Li, Zhijun Xiao, Jian Cai, Weiwei Zhao, Jingjing Duan, Zhen Yang, Zhijun Guo, Yitian Chen, Weijia Cai, Piaopiao Huang, Chaoyong He, Feng Xu   +13 more
doaj   +1 more source

New methods to analyse microarray data that partially lack a reference signal. [PDF]

, 2009
BACKGROUND: Microarray-based Comparative Genomic Hybridisation (CGH) has been used to assess genetic variability between bacterial strains. Crucial for interpretation of microarray data is the availability of a reference to compare signal intensities to ...
Lindsay Jodi A, Fluit, AC, Rob JL Willems, Bonten, MJ, Willems Rob JL, Bonten Marc JM, Ad C Fluit, Carpaij, N, Lindsay, JA, Willems, RJ, Marc JM Bonten, Fluit Ad C, Jodi A Lindsay, Neeltje Carpaij, Carpaij Neeltje   +14 more
core   +1 more source

Analysis of potential genes and pathways associated with the colorectal normal mucosa–adenoma–carcinoma sequence

Cancer Medicine, 2018
This study aimed to identify differentially expressed genes (DEGs) related to the colorectal normal mucosa–adenoma–carcinoma sequence using bioinformatics analysis.
Zhuoxuan Wu, Zhen Liu, Weiting Ge, Jiawei Shou, Liangkun You, Hongming Pan, Weidong Han   +6 more
doaj   +1 more source