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Methylation Analysis by Microarray [PDF]
, 2009 Differential methylation hybridization (DMH) is a high-throughput DNA methylation screening tool that utilizes methylation-sensitive restriction enzymes to profile methylated fragments by hybridizing them to a CpG island microarray. This array contains probes spanning all the 27,800 islands annotated in the UCSC Genome Browser. Herein we describe a DMH
Daniel E, Deatherage +4 more
openaire +2 more sources
CIDA: An integrated software for the design, characterisation and global comparison of microarrays
Journal of Integrative Bioinformatics, 2007 Microarray technology has had a significant impact in the field of systems biology involving the investigation into the biological systems that regulate human life. Identifying genes of significant interest within any given disease on an individual basis
Khalid Sabah +6 more
doaj +1 more source
Differential Gene Sets Profiling in Gram-Negative and Gram-Positive Sepsis
Frontiers in Cellular and Infection Microbiology, 2022 BackgroundThe host response to bacterial sepsis is reported to be nonspecific regardless of the causative pathogen. However, newer paradigms indicated that the host response of Gram-negative sepsis may be different from Gram-positive sepsis, and the ...
Qingliang Wang +7 more
doaj +1 more source
Annotation-based meta-analysis of microarray experiments [PDF]
, 2009 We are developing software applications to perform meta-analysis of microarray experiments based on standardized experiment annotations aiming to identify similar experiments and cluster experiments.
Christian J. Stoeckert, Jr. +3 more
core +2 more sources
Microarray Expression Profiles of lncRNAs and mRNAs in Postoperative Cognitive Dysfunction
Frontiers in Neuroscience, 2018 Postoperative cognitive dysfunction (POCD) is serious disorder in the central nervous system common in aged patients after anesthesia. Although its clinical symptoms are well recognized, however, the molecular etiology of the POCD remains unrevealed ...
Ying Zhang +8 more
doaj +1 more source
Information visualization for DNA microarray data analysis: A critical review [PDF]
, 2008 Graphical representation may provide effective means of making sense of the complexity and sheer volume of data produced by DNA microarray experiments that monitor the expression patterns of thousands of genes simultaneously.
Kuljis, J, Liu, X, Zhang, L
core +1 more source
Frontiers in Oncology, 2021 Circular RNAs (circRNAs) and long noncoding RNAs (lncRNAs) have been considered as biomarkers or regulators in many diseases. However, the exact role of circRNA- or lncRNA-mediated competing endogenous RNA (ceRNA) networks in the modulation of depression
Ting Zhou +13 more
doaj +1 more source
Gene expression reliability estimation through cluster-based analysis [PDF]
, 2009 Gene expression is the fundamental control of the structure and functions of the cellular versatility and adaptability of any organisms. The measurement of gene expressions is performed on images generated by optical inspection of microarray devices ...
Benso, Alfredo +3 more
core +1 more source
Cancer Medicine, 2018 This study aimed to identify differentially expressed genes (DEGs) related to the colorectal normal mucosa–adenoma–carcinoma sequence using bioinformatics analysis.
Zhuoxuan Wu +6 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2022 The ability of blood transcriptome analysis to identify dysregulated pathways and outcome-related genes following myocardial infarction remains unknown.
Hu Zhai +22 more
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