Results 21 to 30 of about 333,655 (268)

Differential Gene Sets Profiling in Gram-Negative and Gram-Positive Sepsis

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
BackgroundThe host response to bacterial sepsis is reported to be nonspecific regardless of the causative pathogen. However, newer paradigms indicated that the host response of Gram-negative sepsis may be different from Gram-positive sepsis, and the ...
Qingliang Wang   +7 more
doaj   +1 more source

Microarray Expression Profiles of lncRNAs and mRNAs in Postoperative Cognitive Dysfunction

open access: yesFrontiers in Neuroscience, 2018
Postoperative cognitive dysfunction (POCD) is serious disorder in the central nervous system common in aged patients after anesthesia. Although its clinical symptoms are well recognized, however, the molecular etiology of the POCD remains unrevealed ...
Ying Zhang   +8 more
doaj   +1 more source

Chronic Stress-Induced Gene Changes In Vitro and In Vivo: Potential Biomarkers Associated With Depression and Cancer Based on circRNA- and lncRNA-Associated ceRNA Networks

open access: yesFrontiers in Oncology, 2021
Circular RNAs (circRNAs) and long noncoding RNAs (lncRNAs) have been considered as biomarkers or regulators in many diseases. However, the exact role of circRNA- or lncRNA-mediated competing endogenous RNA (ceRNA) networks in the modulation of depression
Ting Zhou   +13 more
doaj   +1 more source

Analysis of potential genes and pathways associated with the colorectal normal mucosa–adenoma–carcinoma sequence

open access: yesCancer Medicine, 2018
This study aimed to identify differentially expressed genes (DEGs) related to the colorectal normal mucosa–adenoma–carcinoma sequence using bioinformatics analysis.
Zhuoxuan Wu   +6 more
doaj   +1 more source

Human Plasma Transcriptome Implicates Dysregulated S100A12 Expression: A Strong, Early-Stage Prognostic Factor in ST-Segment Elevated Myocardial Infarction: Bioinformatics Analysis and Experimental Verification

open access: yesFrontiers in Cardiovascular Medicine, 2022
The ability of blood transcriptome analysis to identify dysregulated pathways and outcome-related genes following myocardial infarction remains unknown.
Hu Zhai   +22 more
doaj   +1 more source

Data-Driven Analysis of Age, Sex, and Tissue Effects on Gene Expression Variability in Alzheimer's Disease

open access: yesFrontiers in Neuroscience, 2019
Alzheimer's disease (AD) has been categorized by the Centers for Disease Control and Prevention (CDC) as the 6th leading cause of death in the United States.
Lavida R. K. Brooks, George I. Mias
doaj   +1 more source

The Potential of 2-aza-8-Oxohypoxanthine as a Cosmetic Ingredient

open access: yesCosmetics, 2021
In this study, we verified the effects of 2-aza-8-oxohypoxanthine (AOH) on human epidermal cell proliferation by performing DNA microarray analysis. Cell proliferation was assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide ...
Hisae Aoshima   +3 more
doaj   +1 more source

Combination methods in microarray analysis [PDF]

open access: yes7th International Symposium on Parallel Architectures, Algorithms and Networks, 2004. Proceedings., 2004
Microarray technology and experiment can produce thousands or tens of thousands of gene expression measurements in a single cellular mRNA sample. Selecting a list of informative differential genes from these measurement data has been the central problem for microarray analysis.
Chuang, Han-Yu   +4 more
openaire   +2 more sources

Effects of glucose metabolism on the regulation of genes of fatty acid synthesis and triglyceride secretion in the livers⃞

open access: yesJournal of Lipid Research, 2007
Glucose disposal induces a signal that modulates the transcriptional regulation of genes involved in the glycolysis and lipogenesis pathways. To investigate the role of glucose metabolism on hepatic gene expression independently from insulin action, we ...
Núria Morral   +5 more
doaj   +1 more source

Detection of changes in gene regulatory patterns, elicited by perturbations of the Hsp90 molecular chaperone complex, by visualizing multiple experiments with an animation

open access: yesBioData Mining, 2011
Background To make sense out of gene expression profiles, such analyses must be pushed beyond the mere listing of affected genes. For example, if a group of genes persistently display similar changes in expression levels under particular experimental ...
Echeverría Pablo C   +4 more
doaj   +1 more source

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