Results 31 to 40 of about 333,655 (268)

Evaluating the green credentials and performance of deep eutectic solvents in the extraction of antibiotics and mycotoxins in foods

open access: yesGreen Chemistry Letters and Reviews
Deep eutectic solvents (DES) are new generation solvents that have recently emerged as a sustainable alternative to organic solvents in the extraction of chemical contaminants in foods.
Oluwatobi Kolawole   +5 more
doaj   +1 more source

Changing paradigms of anti-VEGF in the Indian scenario

open access: yesIndian Journal of Ophthalmology, 2014
Anti-vascular endothelial growth factors (VEGF) agents have revolutionized the treatment of retinal diseases. Use of anti-VEGF agents in the Indian Scenario present some unique challenges considering the absence of compounding pharmacies, poor penetrance
P Mahesh Shanmugam
doaj   +1 more source

Gene Expression Profile Induced by Two Different Variants of Street Rabies Virus in Mice

open access: yesViruses, 2022
Pathogenicity and pathology of rabies virus (RABV) varies according to the variant, but the mechanisms are not completely known. In this study, gene expression profile in brains of mice experimentally infected with RABV isolated from a human case of dog ...
Camila M. Appolinário   +5 more
doaj   +1 more source

Microarray analysis in cystic fibrosis [PDF]

open access: yesJournal of Cystic Fibrosis, 2004
DNA microarrays provide a versatile platform for applications including gene expression analysis and genotyping. In the case of cystic fibrosis (CF), DNA microarrays enable the measurement of gene expression levels of thousands of genes in parallel, and potentially therefore, to identify non-CFTR genes down- or up-regulated in CF, which could lead to ...
Galvin, Paul   +3 more
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Microarray Analysis Using the MicroArray Explorer [PDF]

open access: yes, 2003
The MicroArray Explorer (MAExplorer) is an open-source Java-based microarray data-mining tool that is available from the open source Web site as both a ready-to-run program and source code from http://maexplorer.sourceforge.net/. MAExplorer helps analyze expression patterns of individual genes, gene families, and clusters of genes.
Peter F. Lemkin   +2 more
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Monitoring the Efficacy of Oncolytic Viruses via Gene Expression

open access: yesFrontiers in Oncology, 2017
With the recent success of oncolytic viruses in clinical trials, efforts toward improved monitoring of the viruses and their mechanism have intensified.
Ashley Ansel   +3 more
doaj   +1 more source

Global transcriptional response of oral squamous cell carcinoma cell lines to health-associated oral bacteria - an in vitro study

open access: yesJournal of Oral Microbiology, 2022
Background We have recently demonstrated that health-associated oral bacteria Streptococcus mitis, Neisseria flavescens, and Haemophilus parainfluenzae induce cytotoxicity in oral squamous cell carcinoma (OSCC) cell lines and downregulate CD36, a cancer ...
Divyashri Baraniya   +2 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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