Results 71 to 80 of about 22,889,079 (421)
Network Analysis of Microarray Data
, 2021 DNA microarrays are widely used to investigate gene expression. Even though the classical analysis of microarray data is based on the study of differentially expressed genes, it is well known that genes do not act individually. Network analysis can be applied to study association patterns of the genes in a biological system.
Pavel, Alisa +4 more
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Journal of the American Medical Association (JAMA), 2015 IMPORTANCE The use of genome-wide tests to provide molecular diagnosis for individuals with autism spectrum disorder (ASD) requires more study.
K. Tammimies +33 more
semanticscholar +1 more source
Identification of Key Genes and Pathways in Post-traumatic Stress Disorder Using Microarray Analysis
Frontiers in Psychology, 2019 Introduction: Post-traumatic stress disorder (PTSD) is characterized by impaired fear extinction, excessive anxiety, and depression. However, the potential pathogenesis and cause of PTSD are not fully understood.
Yaoyao Bian +9 more
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GEE: An Informatics Tool for Gene Expression Data Explore [PDF]
Healthcare Informatics Research, 2016 ObjectivesMajor public high-throughput functional genomic data repositories, including the Gene Expression Omnibus (GEO) and ArrayExpress have rapidly expanded.
Soo Youn Lee +4 more
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Technical Analysis of cDNA Microarrays
PLoS ONE, 2009 There is extensive variation in gene expression among individuals within and between populations. Accurate measures of the variation in mRNA expression using microarrays can be confounded by technical variation, which includes variation in RNA isolation procedures, day of hybridization and methods used to amplify and dye label RNA for hybridization.In ...
Jeff VanWye +3 more
openaire +5 more sources
Physics-based analysis of Affymetrix microarray data
, 2006 We analyze publicly available data on Affymetrix microarrays spike-in experiments on the human HGU133 chipset in which sequences are added in solution at known concentrations. The spike-in set contains sequences of bacterial, human and artificial origin.
Barkema, G. T. +3 more
core +1 more source
Gene expression reliability estimation through cluster-based analysis [PDF]
, 2009 Gene expression is the fundamental control of the structure and functions of the cellular versatility and adaptability of any organisms. The measurement of gene expressions is performed on images generated by optical inspection of microarray devices ...
Benso, Alfredo +3 more
core +1 more source
Microarray Analysis of Gene Expression in Chondrosarcoma Cells Stimulated with Bee Venom
Journal of Pharmacopuncture, 2004 봉독은 관절염 치료를 비롯한 여러 질환에 그 응용범위가 넓어지고 있으며 기전규명과 새로운 치료효과 개발을 위한 연구가 필요하다. 연골의 파괴는 진행된 각종 관절병증의 공통 병리기전이며 연골세포의 기능이상은 이 기전에 중요한 의미를 지닌다. 사람 연골세포의 특성을 유지하고 있는 HTB-94 연골육종세포를 배양하고 봉독을 처치했을 때의 유전자 발현양상을 microarray를 이용하여 관찰하였다. 대조군에 비해 4배 이상 발현의 차이가 있는 경우를 유의한
Yin, Changshik, Koh, Hyung-gyun
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Functional Profiling of Human MeCP2 by Automated Data Comparison Analysis and Computerized Expression Pathway Modeling [PDF]
Healthcare Informatics Research, 2016 ObjectivesMethyl-CpG binding protein 2 (MeCP2) is a ubiquitous epigenetic factor that represses gene expression by modifying chromatin. Mutations in the MeCP2 gene cause Rett syndrome, a progressive neurodevelopmental disorder.
Injoo Kim +5 more
doaj +1 more source
LncRNA RP11-59J16.2 aggravates apoptosis and increases tau phosphorylation by targeting MCM2 in AD
Frontiers in Genetics, 2022 Alzheimer’s disease (AD) is a degenerative disease of central nervous system with unclear pathogenesis, accounting for 60%–70% of dementia cases. Long noncoding RNAs (LncRNAs) play an important function in the development of AD.
Fulin Guan +5 more
doaj +1 more source