Results 61 to 70 of about 594,887 (306)
A note on between-group PCA [PDF]
, 2004 In the context of binary classification with continuous predictors, we proove two properties concerning the connections between Partial Least Squares (PLS) dimension reduction and between-group PCA, and between linear discriminant analysis and between ...
Boulesteix, Anne-Laure
core +3 more sources
Microarray Analysis Using the MicroArray Explorer [PDF]
, 2003 The MicroArray Explorer (MAExplorer) is an open-source Java-based microarray data-mining tool that is available from the open source Web site as both a ready-to-run program and source code from http://maexplorer.sourceforge.net/. MAExplorer helps analyze expression patterns of individual genes, gene families, and clusters of genes.
Peter F. Lemkin +2 more
openaire +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Cancer ReportsObjectives The primary aim of this research is to identify and describe the distinct patterns of microRNAs (miRNAs) that are unusually expressed in benign prostatic hyperplasia (BPH) tissues compared to normal prostatic tissues. Materials and Methods The
Lingmin Song +4 more
doaj +1 more source
Aberrations of the number of copies (CNA) in the genome of luminal B breast tumor
Бюллетень сибирской медицины, 2020 Aim. To describe the CNA (Copy Number Aberration) landscape of luminal B breast tumor before treatment.Materials and methods. The study included 100 patients with breast cancer (BC) of luminal B subtype for which a biopsy of the tumor material was ...
M. K. Ibragimova +3 more
doaj +1 more source
The latent process decomposition of cDNA microarray data sets [PDF]
, 2005 We present a new computational technique (a software implementation, data sets, and supplementary information are available at http://www.enm.bris.ac.uk/lpd/) which enables the probabilistic analysis of cDNA microarray data and we demonstrate its ...
, +4 more
core +2 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Assessment of SVM Reliability for Microarray Data Analysis [PDF]
, 2004 The goal of our research is to provide techniques that can assess and validate the results of SVM-based analysis of microarray data. We present preliminary results of the effect of mislabeled training samples.
Blanzieri, Enrico +2 more
core
Analysis of variance components reveals the contribution of sample processing to transcript variation [PDF]
, 2009 The proper design of DNA microarray experiments requires knowledge of biological and technical variation of the studied biological model. For the filamentous fungus Aspergillus niger, a fast, quantitative real-time PCR (qPCR)-based hierarchical ...
Veen, D., van der +3 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source