Results 71 to 80 of about 594,887 (306)
Identification of Key Genes and Pathways in Post-traumatic Stress Disorder Using Microarray Analysis
Frontiers in Psychology, 2019 Introduction: Post-traumatic stress disorder (PTSD) is characterized by impaired fear extinction, excessive anxiety, and depression. However, the potential pathogenesis and cause of PTSD are not fully understood.
Yaoyao Bian +9 more
doaj +1 more source
Biomedicines, 2023 Transcriptomic evidence from human myocardium in myocardial infarction (MI) is still not sufficient. Thus, there is a need for studies on human cardiac samples in relation to the clinical data of patients.
Vyacheslav Ryabov +6 more
doaj +1 more source
Coincidence between transcriptome analyses on different microarray platforms using a parametric framework [PDF]
, 2008 A parametric framework for the analysis of transcriptome data is demonstrated to yield coincident results when applied to data acquired using two different microarray platforms.
Tomokazu Konishi +26 more
core +3 more sources
Serendipitous discoveries in microarray analysis [PDF]
BMC Bioinformatics, 2010 Background Scientists are capable of performing very large scale gene expression experiments with current microarray technologies. In order to find significance in the expression data, it is common to use clustering algorithms to group genes with similar expression patterns. Clusters will often contain related genes, such as co-regulated genes or genes
Sally R. Ellingson +6 more
openaire +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
A comparative study of different strategies of batch effect removal in microarray data: a case study of three datasets [PDF]
, 2013 Batch effects refer to the systematic non-biological variability that is introduced by experimental design and sample processing in microarray experiments.
Ding, Fei
core
GeneRank: Using search engine technology for the analysis of microarray experiments [PDF]
, 2005 Copyright @ 2005 Morrison et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use ...
Breitling, R +3 more
core +5 more sources
Preparation and Analysis of Glycan Microarrays [PDF]
Current Protocols in Protein Science, 2011 AbstractDetermination of the binding specificity of glycan‐binding proteins (GBPs), such as lectins, antibodies, and receptors, has traditionally been difficult and laborious. The advent of glycan microarrays has revolutionized the field of glycobiology by allowing simultaneous screening of a GBP for interactions with a large set of glycans in a single
Jamie, Heimburg-Molinaro +3 more
openaire +2 more sources
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source