Results 91 to 100 of about 594,887 (306)

Does Logarithm Transformation of Microarray Data Affect Ranking Order of Differentially Expressed Genes?

, 2006
A common practice in microarray analysis is to transform the microarray raw data (light intensity) by a logarithmic transformation, and the justification for this transformation is to make the distribution more symmetric and Gaussian-like.
Li, Wentian, Suh, Young Ju, Zhang, Jingshan   +2 more
core   +1 more source

A Pathway Analysis Tool for Analyzing Microarray Data of Species with Low Physiological Information [PDF]

, 2008
Pathway information provides insight into the biological processes underlying microarray data. Pathway information is widely available for humans and laboratory animals in databases through the internet, but less for other species, for example, livestock.
Pas, M.F.W., te, Hemert, S., van, Hulsegge, B., Hoekman, A.J.W., Pool, M.H., Rebel, J.M.J., Smits, M.A.   +6 more
core   +3 more sources

Parallel 3D Bioprinting on SLIPS‐Microarrays

Advanced Functional Materials, EarlyView.
This work introduces the first truly parallel 3D bioprinting method, enabling both the simultaneous fabrication of hundreds of cell laden hydrogel 3D structures and their HTS in individual liquid compartments. By integrating Digital Light Processing (DLP) stereolithography with functional micropatterns, the platform decouples printing time from array ...
Julius von Padberg, Julian A. Serna, Maike Schliephake, Pavel A. Levkin   +3 more
wiley   +1 more source

Microarray Analysis of Gene Expression in Chondrosarcoma Cells Stimulated with Bee Venom

Journal of Pharmacopuncture, 2004
봉독은 관절염 치료를 비롯한 여러 질환에 그 응용범위가 넓어지고 있으며 기전규명과 새로운 치료효과 개발을 위한 연구가 필요하다. 연골의 파괴는 진행된 각종 관절병증의 공통 병리기전이며 연골세포의 기능이상은 이 기전에 중요한 의미를 지닌다. 사람 연골세포의 특성을 유지하고 있는 HTB-94 연골육종세포를 배양하고 봉독을 처치했을 때의 유전자 발현양상을 microarray를 이용하여 관찰하였다. 대조군에 비해 4배 이상 발현의 차이가 있는 경우를 유의한
Yin, Changshik, Koh, Hyung-gyun
doaj   +1 more source

Design Strategies and Emerging Applications of High‐Performance Flexible Piezoresistive Pressure Sensors

Advanced Functional Materials, EarlyView.
Flexible piezoresistive pressure sensors underpin wearable and soft electronics. This review links sensing physics, including contact resistance modulation, quantum tunneling and percolation, to unified materials/structure design. We highlight composite and graded architectures, interfacial/porous engineering, and microstructured 3D conductive networks
Feng Luo, Artur Ciesielski, Paolo Samorì   +2 more
wiley   +1 more source

Genome-wide microRNA and gene analysis of mesenchymal stem cell chondrogenesis identifies an essential role and multiple targets for miR-140-5p [PDF]

, 2015
microRNAs (miRNAs) are abundantly expressed in development where they are critical determinants of cell differentiation and phenotype. Accordingly miRNAs are essential for normal skeletal development and chondrogenesis in particular.
Akiyama, Albers, Baek, Baraniskin, Bartel, Barter, Berschneider, Bhushan, Bi, Boland, Chiang, Chun, DeLise, Djebali, Dongen, Eberhart, Ebert, Feigin, Friedman, Fu, Furumatsu, Golan, Gradus, Grumolato, Hwang, Jenkins, Kai, Kanamori, Karlsen, Karlsson, Kolben, Korinek, Krol, Laine, Lalevee, Li, Li, Liu, Liu, Lyons, Miyaki, Miyaki, Murdoch, Nakamura, Onyekwelu, Pais, Parikh, Pittenger, Radwan, Roelofs, Rui, Schulz, Smyth, Song, Sorrentino, Staines, Sumiyoshi, Swingler, Tardif, Taylor, Tuddenham, Vonk, Wang, Wang, Xu, Yamashita, Yang, Yang, Yano, Yuan, Zeybel, Zhang, Zhang   +72 more
core   +1 more source

Functional Precision Oncology Approach Using Nanoliter Droplet Array for Drug Sensitivity Testing in Lung Cancer

Advanced Healthcare Materials, EarlyView.
A miniaturized drug sensitivity and resistance testing (DSRT) workflow based on the Droplet Microarray (DMA) platform enables functional drug testing using minimal patient‐derived tumor material. By screening nanoliter‐scale droplets containing as few as 300 cells, this approach generates reproducible and tumor‐specific drug response profiles ...
Maryam Salarian, Vicky L. Schiling, Thomas Muley, Michael Allgäuer, Florian Eichhorn, Michael Meister, Marc A. Schneider, Anna A. Popova   +7 more
wiley   +1 more source

Differential Gene Expression in Brain and Liver Tissue of Wistar Rats after Rapid Eye Movement Sleep Deprivation

Clocks & Sleep, 2020
Sleep is essential for the survival of most living beings. Numerous researchers have identified a series of genes that are thought to regulate “sleep-state” or the “deprived state”. As sleep has a significant effect on physiology, we believe that lack of
Atul Pandey, Ryan Oliver, Santosh K Kar
doaj   +1 more source

A cDNA Microarray Gene Expression Data Classifier for Clinical Diagnostics Based on Graph Theory [PDF]

, 2011
Despite great advances in discovering cancer molecular profiles, the proper application of microarray technology to routine clinical diagnostics is still a challenge. Current practices in the classification of microarrays' data show two main limitations:
Benso, Alfredo, Di Carlo, Stefano, Politano, Gianfranco Michele Maria   +2 more
core   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source