Results 101 to 110 of about 19,288,705 (257)

GeneRank: Using search engine technology for the analysis of microarray experiments [PDF]

, 2005
Copyright @ 2005 Morrison et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use ...
Morrison Julie L, Desmond J Higham, Morrison, J.L., Breitling, Rainer, Gilbert, D, Breitling, R., Rainer Breitling, Gilbert, David R., Breitling, R, Gilbert, David R, Breitling Rainer, Higham, Desmond J, Higham, Desmond J., Morrison, Julie L., Gilbert, D.R., Julie L Morrison, Higham Desmond J, Morrison, Julie L, David R Gilbert, Morrison, JL, Gilbert David R, Higham, D.J., Higham, D   +22 more
core   +2 more sources

HLA‐DR+ Schwann Cells Generate the Protumor Cancer‐Neuron‐Immune Niche in Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
Hijacked and educated by HNSCC cells, HLA‐DR+ Schwann cells lost their normal neural‐related functions but acquired immunoregulatory phenotypes to promote CD4+ T cells transform into Tregs. HLA‐DR+ Schwann cells induced a macrophage subpopulation, Il1β.
Xiaoyan Meng, Zhonglong Liu, Shijian Zhang, Luoman Gan, Liren Cao, Jingjing Sun, Lingfang Zhang, Yue He   +7 more
wiley   +1 more source

Influence of ovarian hormones deprivation on gene expression in the lower urinary tract of rats

International Brazilian Journal of Urology, 2007
OBJECTIVE: Identify the influence of ovarian hormone deprivation in expression genes on the lower urinary tract of rats. MATERIALS AND METHODS: This study deals with gene screening on lower urinary tract of rats. Fifty isogenic rats divided in two groups
Maria A. T. Bortolini, Ismael D. C. Silva, Maria G. Hamerski, Rodrigo A. Castro, Marair G. F. Sartori, Manoel J. B. Girao   +5 more
doaj   +1 more source

Bioinformatics protocols for analysis of functional genomics data applied to neuropathy microarray datasets [PDF]

, 2010
Microarray technology allows the simultaneous measurement of the abundance of thousands of transcripts in living cells. The high-throughput nature of microarray technology means that automatic analytical procedures are required to handle the sheer ...
Diboun, I.
core  

RNA‐Binding Protein RBM25 Targets the mRNA Stability of GTPase Rab22a to Restrict Viral Entry and Infection

Advanced Science, EarlyView.
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding, Huiying Chen, Yuyu Jiang, Chunyan Zhao, Jie Bai, Yan Xiang, Zeting Wang, Xixi Wang, Bing Rui, Wanda Tang, Yue Ding, Zhenzhen Zhan, Yunkai Zhang, Xingguang Liu   +13 more
wiley   +1 more source

Transcriptomic Analysis of Copper Resistance in Saccharomyces cerevisiae: Insights into Adaptive Evolution and Potential Implications for Wood Preservative Treatments

Antibiotics
Background/Objectives: Copper-based wood preservatives are widely used to protect timber from fungal decay; however, the emergence of copper-tolerant fungi reduces their long-term effectiveness.
Kusung Chung, Tae-Jong Kim
doaj   +1 more source

Condition‐Associated Pattern Extraction and Recovery From Multi‐Condition Single‐Cell RNA‐seq Data With CAPER

Advanced Science, EarlyView.
Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li, Jin Ning, An Wang, Minxi Shi, Yuanze Chen, Guoliang Liu, Shiquan Sun   +6 more
wiley   +1 more source

Genome‐wide allele‐ and strand‐specific expression profiling

Molecular Systems Biology, 2009
Recent reports have shown that most of the genome is transcribed and that transcription frequently occurs concurrently on both DNA strands. In diploid genomes, the expression level of each allele conditions the degree to which sequence polymorphisms ...
Julien Gagneur, Himanshu Sinha, Fabiana Perocchi, Richard Bourgon, Wolfgang Huber, Lars M Steinmetz   +5 more
doaj   +1 more source

Listen to genes : dealing with microarray data in the frequency domain [PDF]

, 2009
Background: We present a novel and systematic approach to analyze temporal microarray data. The approach includes normalization, clustering and network analysis of genes.
Guo Shuixia, Dongyun Yi, Ritesh Krishna, Yi, Dongyun, Buchanan-Wollaston, Vicky, Yi Dongyun, Shuixia Guo, Feng, Jianfeng, Jianfeng Feng, Guo, Shuixia, Krishna, Ritesh, Vicky Buchanan-Wollaston, Krishna Ritesh, Buchanan-Wollaston Vicky, Feng Jianfeng   +14 more
core   +1 more source

Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

Advanced Science, EarlyView.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li, Zhongya Zhai, Haiyi Yu, Renjie Qiu, Fengyu Li, Luxi Xiao, Boxi Huang, Huiying Liu, Jiayong He, Bowen Cai, Jiawen Chen, Jiang Yu, Guoxin Li, Tao Chen   +13 more
wiley   +1 more source