Nanostructured Protein Surfaces Inspired by Spider Silk
Harnessing recombinant spider silk technology, bioengineered spidroin variants enable the creation of functionalized nanostructured coatings with tunable affinity for specific targets, supporting a broad range of applications ‐ from antifouling surfaces and targeted drug delivery to advanced cell therapies and precision bio‐patterning via lithography ...
Martin Humenik, Thomas Scheibel
wiley +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa+3 more
wiley +1 more source
A Review Study of Microarray Data Classification with the Application of Dimension Reduction
Background. The growth of gene expression or microarray data, mainly in cancer disease, has become a game changer for feature selection techniques in handling complex data.
Sharifah Nadia Syed Hasan+1 more
doaj
Automatic Spot Adressing in cDNA Microarray Images
Complementary DNA (cDNA) microarrays are a powerful high throughput technology developed in the last decade allowing researchers to analyze the behaviour and interaction of thousands of genes simultaneously.
Mónica G. Larese, Juan Carlos Gómez
doaj
Optimization of gene expression microarray protocol for formalin-fixed paraffin-embedded tissues
Formalin-fixed paraffin-embedded (FFPE) tissue is a widely available clinical specimen for retrospective studies. The possibility of long-term clinical follow-up of FFPE samples makes them a valuable source to evaluate links between molecular and ...
Nevin Belder+5 more
doaj +1 more source
Ultra‐High‐Throughput Nanoliter‐Scale Liquid‐Liquid Extractions and Reaction Mixture Purification
This work presents a novel approach for the extraction or addition of substances and purification of chemical synthesis in a miniaturized, high‐throughput (HT) manner. It is based on high droplet stability on the Droplet Microarray (DMA), allowing the complete immersion of a miniaturized array with up to 2688 15 nL‐droplets into an organic solvent and ...
Michelle J. Iwohn+2 more
wiley +1 more source
Detecting microRNA activity from gene expression data
Background MicroRNAs (miRNAs) are non-coding RNAs that regulate gene expression by binding to the messenger RNA (mRNA) of protein coding genes. They control gene expression by either inhibiting translation or inducing mRNA degradation.
Fitzgerald Katherine A+6 more
doaj +1 more source
Comparative analysis of genes regulated in acute myelomonocytic leukemia with and without inv(16)(p13q22) using microarray techniques, real-time PCR, immunohistochemistry, and flow cytometry immunophenotyping [PDF]
Xiaoping Sun+9 more
openalex +1 more source
This review explores recent developments in micro/nanostructured surfaces, with a focus on cavity‐based and reentrant geometries for enhanced liquid repellency and interfacial control. The review discusses fabrication strategies, structural design principles, and application trends, providing a balanced perspective on opportunities and ongoing ...
Seo Rim Park+11 more
wiley +1 more source
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao+6 more
wiley +1 more source