Genome-Wide Analysis of Pancreatic Cancer Using Microarray-Based Techniques
Pancreatology, 2009Microarray-based comparative genomic hybridisation (CGH) has allowed high-resolution analysis of DNA copy number alterations across the entire cancer genome. Recent advances in bioinformatics tools enable us to perform a robust and highly sensitive analysis of array CGH data and facilitate the discovery of novel cancer-related genes.We analysed a total
Claude Chelala+3 more
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Single Nucleotide Polymorphism Analysis in HIV and Kaposi's Sarcoma Disease by Microarray Technique
Current HIV Research, 2020Background: Emergence of Kaposi's Sarcoma in the cases other than HIV, following the use of immunosuppressant drugs, demonstrates that it is related to weak immunity. The fact that this malignancy does not occur in every HIV-positive patient suggests that genetic predisposition may also be effective.
Ismail Koyuncu+6 more
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Analysis of Gene Expression Discretization Techniques in Microarray Biclustering
2017Gene expression biclustering analysis is a commonly used technique to see the interaction between genes under certain experiments or conditions. More specifically in the study of diseases, these methods are used to compare control and affected data in order to identify the involved or relevant genes.
Cristian Andrés Gallo+3 more
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Performance analysis of clustering techniques over microarray data: A case study
Physica A: Statistical Mechanics and its Applications, 2018Abstract Handling big data is one of the major issues in the field of statistical data analysis. In such investigation cluster analysis plays a vital role to deal with the large scale data. There are many clustering techniques with different cluster analysis approach. But which approach suits a particular dataset is difficult to predict. To deal with
Bijan Bihari Misra, Rasmita Dash
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Similarity analysis of feature ranking techniques on imbalanced DNA microarray datasets
2012 IEEE International Conference on Bioinformatics and Biomedicine, 2012DNA microarrays are a modern advancement in the analysis of genetic data. This technology allows a researcher to test samples for thousands of genes simultaneously. However, once the samples in the DNA microarrays have been tested, the researcher must then search through the data collected and identify genes important to their problem.
Randall Wald+3 more
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The optimized adaptive density estimation technique applied to microarray data analysis
2014 International Conference on Multimedia Computing and Systems (ICMCS), 2014This paper describes and proposes a method of optimizing the smoothing parameter of an estimator of the probability density function (PDF) called the adaptive kernel estimator (AKE). This optimized estimator is used to build the Bayes classifier in the classification of microarray data. The study profiles and gene expression have made great advances in
Yissam Lakhdar, El Hassan Sbai
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Microarrays are among the most powerful tools in biological research, but in order to attain its full potentialities, it is imperative to develop techniques capable to effectively exploit the huge quantity of data which they produce. In this paper two machine learning methodologies for microarray data analysis are proposed: (1) Probabilistic Principal ...
AMATO R.+9 more
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An improved SOM-based visualization technique for DNA microarray data analysis
The 2010 International Joint Conference on Neural Networks (IJCNN), 2010Effective and meaningful visualization techniques are quite important for multidimensional DNA microarray gene expression data analysis. Elucidating the cluster properties of these multidimensional data are often complex. Patterns, hypotheses on the relationships, and ultimately of the function of the gene can be analyzed and visualized by non-linear ...
Pramod Kumar Meher+3 more
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Performance Analysis of Microarray Data Classification using Machine Learning Techniques
International Journal of Knowledge Discovery in Bioinformatics, 2015Microarray technology of DNA permits simultaneous monitoring and determining of thousands of gene expression activation levels in a single experiment. Data mining technique such as classification is extensively used on microarray data for medical diagnosis and gene analysis.
Ajay Kumar Mishra+2 more
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Comparative study on dimension reduction techniques for cluster analysis of microarray data
The 2011 International Joint Conference on Neural Networks, 2011This paper proposes a study on the impact of the use of dimension reduction techniques (DRTs) in the quality of partitions produced by cluster analysis of microarray datasets. We tested seven DRTs applied to four microarray cancer datasets and ran four clustering algorithms using the original and reduced datasets. Overall results showed that using DRTs
Daniel Araújo+3 more
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