Results 21 to 30 of about 89,130 (269)

High throughput genetic analysis of congenital myasthenic syndromes using resequencing microarrays. [PDF]

PLoS ONE, 2007
The use of resequencing microarrays for screening multiple, candidate disease loci is a promising alternative to conventional capillary sequencing. We describe the performance of a custom resequencing microarray for mutational analysis of Congenital ...
Lisa Denning, Jennifer A Anderson, Ryan Davis, Jeffrey P Gregg, Jennifer Kuzdenyi, Ricardo A Maselli   +5 more
doaj   +1 more source

A Fully Automated Gridding Technique for Real Composite cDNA Microarray Images

IEEE Access, 2020
Genome-wide screening using microarrays of DNA will be of great use in the early diagnosis of diseases such as cancer and HIV. It also makes use of gene discovery, pharmacogenomics, toxicogenomics, and nutrigenomics for other applications.
Steffy Maria Joseph, P. S. Sathidevi
doaj   +1 more source

Chromosomal microarrays testing in children with developmental disabilities and congenital anomalies

Jornal de Pediatria, 2015
OBJECTIVES: Clinical use of microarray-based techniques for the analysis of many developmental disorders has emerged during the last decade. Thus, chromosomal microarray has been positioned as a first-tier test. This study reports the first experience in
Guillermo Lay-Son, Karena Espinoza, Cecilia Vial, Juan C. Rivera, María L. Guzmán, Gabriela M. Repetto   +5 more
doaj   +3 more sources

Automatic Spot Identification Method for High Throughput Surface Plasmon Resonance Imaging Analysis

Biosensors, 2018
An automatic spot identification method is developed for high throughput surface plasmon resonance imaging (SPRi) analysis. As a combination of video accessing, image enhancement, image processing and parallel processing techniques, the method can ...
Zhiyou Wang, Xiaoqing Huang, Zhiqiang Cheng   +2 more
doaj   +1 more source

EMAAS: An extensible grid-based Rich Internet Application for microarray data analysis and management

BMC Bioinformatics, 2008
Background Microarray experimentation requires the application of complex analysis methods as well as the use of non-trivial computer technologies to manage the resultant large data sets.
Aitman T, Tomlinson C, Tiwari B, Sherman BT, Saleem A, Mack-Smith J, Krznaric M, Huang Y, Huang DW, Chiba N, Abbott J, Barton G, Darlington J, Game L, Sternberg MJE, Butcher SA   +15 more
doaj   +1 more source

The clinical, cytogenetics and molecular characterization of inverted duplication/deletion of chromosome 8p in a boy with mental and motor retardation: Genotype-phenotype correlation in a case report

Egyptian Journal of Medical Human Genetics, 2018
Background: Rearrangements that occur mainly through the non-allelic homologous recombination (NAHR) during maternal meiosis in short arms of chromosome 8 is relatively associated with various clinical spectrum.
Fatma Silan, Romyla Bourouba, Taner Karakaya, Onur Yildiz, Baris Paksoy, Mine Urfali, Ozturk Ozdemir   +6 more
doaj   +1 more source

New array approaches to explore single cells genomes

Frontiers in Genetics, 2012
Microarray analysis enables the genome wide detection of copy number variations and the investigation of chromosomal instability. Whereas array techniques have been well established for the analysis of unamplified DNA derived from many cells, it has been
Evelyne eVanneste, Lilach eBittman, Niels eVan der Aa, Thierry eVoet, Joris Robert Vermeesch   +4 more
doaj   +1 more source

Computational Intelligence Techniques for Classification in Microarray Analysis [PDF]

, 2010
During the last few years there has been a growing need for using computational intelligence techniques to analyze microarray data. The aim of the system presented in this study is to provide innovative decision support techniques for classifying data from microarrays and for extracting knowledge about the classification process.
Paz Santana, Juan Francisco de, Bajo Pérez, Javier, Rodríguez González, Sara, Corchado Rodríguez, Juan Manuel   +3 more
openaire   +2 more sources

Gene expression levels assessed by oligonucleotide microarray analysis and quantitative real-time RT-PCR – how well do they correlate?

BMC Genomics, 2005
Background The use of microarray technology to assess gene expression levels is now widespread in biology. The validation of microarray results using independent mRNA quantitation techniques remains a desirable element of any microarray experiment.
Boag Joanne M, Freitas Joseph R, Terry Philippa A, Hoffmann Katrin, Beesley Alex H, Firth Martin J, Gottardo Nicholas G, Dallas Peter B, Cummings Aaron J, Kees Ursula R   +9 more
doaj   +1 more source

Comparison of microarray and SAGE techniques in gene expression analysis of human glioblastoma [PDF]

Cytology and Genetics, 2007
To enhance glioblastoma (GB) marker discovery we compared gene expression in GB with human normal brain (NB) by accessing SAGE Genie web site and compared obtained results with published data. Nine GB and five NB SAGE-libraries were analyzed using the Digital Gene Expression Displayer (DGED), the results of DGED were tested by Northern blot analysis ...
Kavsan, V.M., Dmitrenko, V.V., Shostak, K.O., Bukreieva, T.V., Vitak, N.Y., Simirenko, O.E., Malisheva, T.A., Shamayev, M.I., Rozumenko, V.D., Zozulyay, Y.A.   +9 more
openaire   +3 more sources