Results 31 to 40 of about 27,010,024 (292)

FiGS: a filter-based gene selection workbench for microarray data

open access: yesBMC Bioinformatics, 2010
Background The selection of genes that discriminate disease classes from microarray data is widely used for the identification of diagnostic biomarkers. Although various gene selection methods are currently available and some of them have shown excellent
Yun Taegyun   +3 more
doaj   +1 more source

Bioinformatics Techniques in Microarray Research: Applied Microarray Data Analysis Using R and SAS Software [PDF]

open access: yes, 2010
Exploration of the underlying biological mechanisms of disease is useful for many purposes such as the development of novel treatment modalities in addition to informing on-going risk factor research. DNA-microarray technology is a relatively recent and novel approach to conducting genome-wide gene expression studies to identify previously unknown ...
Ryan T, Demmer   +2 more
openaire   +2 more sources

New array approaches to explore single cells genomes

open access: yesFrontiers in Genetics, 2012
Microarray analysis enables the genome wide detection of copy number variations and the investigation of chromosomal instability. Whereas array techniques have been well established for the analysis of unamplified DNA derived from many cells, it has been
Evelyne eVanneste   +4 more
doaj   +1 more source

Microarray analysis in the Archaeon Halobacterium salinarum strain R1 [PDF]

open access: yes, 2007
Background: Phototrophy of the extremely halophilic archaeon Halobacterium salinarum was explored for decades. The research was mainly focused on the expression of bacteriorhodopsin and its functional properties.
Wende Andy   +35 more
core   +1 more source

Optimization of Cyanine Dye Stability and Analysis of FRET Interaction on DNA Microarrays

open access: yesBiology, 2016
The application of DNA microarrays for high throughput analysis of genetic regulation is often limited by the fluorophores used as markers. The implementation of multi-scan techniques is limited by the fluorophores’ susceptibility to photobleaching when ...
Marcel von der Haar   +6 more
doaj   +1 more source

Evaluation of the Tissue Microarray Technique for Immunohistochemical Analysis in Rectal Cancer

open access: yesArchives of Pathology & Laboratory Medicine, 2002
Abstract Background. —Immunohistochemical staining for tumor-associated proteins is widely used for the identification of novel prognostic markers. Recently, a tissue-conserving, high-throughput technique, tissue microarray, has been introduced.
Eva, Fernebro   +4 more
openaire   +2 more sources

Comprehensive Review of Hybrid Feature Selection Methods for Microarray-Based Cancer Detection

open access: yesIEEE Access
Microarray data-based cancer detection advances early diagnosis and personalized medicine by utilizing gene expression data to develop comprehensive cancer profiles, measuring thousands of genes simultaneously.
Azka Khoirunnisa   +3 more
doaj   +1 more source

Comparison of different probe-level analysis techniques for oligonucleotide microarrays

open access: yesBioTechniques, 2004
Three different software packages for the probe-level analysis of high-density oligonucleotide microarray data were compared using an experiment-derived data set that was validated using real-time PCR. The efficiency with which these three programs could identify true positives in this data set was assessed. In addition, estimates of false-positive and
Barbara Rosati   +4 more
openaire   +3 more sources

Application of chromosome microarray analysis and karyotyping in fetal cardiac abnormalities

open access: yesFrontiers in Genetics
ObjectiveChromosome microarray analysis (CMA) and karyotyping are two important genetic testing techniques used in prenatal diagnosis. This study aims to evaluate the value of chromosome microarray analysis and karyotyping in the diagnosis of fetal ...
Yun Guo   +3 more
doaj   +1 more source

Pro-MAP: a robust pipeline for the pre-processing of single channel protein microarray data

open access: yesBMC Bioinformatics, 2022
Background The central role of proteins in diseases has made them increasingly attractive as therapeutic targets and indicators of cellular processes. Protein microarrays are emerging as an important means of characterising protein activity.
Metoboroghene Oluwaseyi Mowoe   +6 more
doaj   +1 more source

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