Results 51 to 60 of about 187,728 (325)

Combination of small molecule microarray and confocal microscopy techniques for live cell staining fluorescent dye discovery [PDF]

, 2013
Discovering new fluorochromes is significantly advanced by high-throughput screening (HTS) methods. In the present study a combination of small molecule microarray (SMM) prescreening and confocal laser scanning microscopy (CLSM) was developed in order to
Attila Bokros, Begüm Peksel, Bhavyashree Suresh, Eszter Molnár, Ferhan Ayaydin, Gabriella Fábián, Liliána Z. Fehér, László G. Puskás, Pradeep Kumar Reddy Cingaram, Soujanya Kuntam, Ágnes Medgyesi   +10 more
core   +2 more sources

Clustering column-mean quantile median: a new methodology for imputing missing data

Journal of Engineering and Applied Science, 2022
DNA microarray data sets have been widely explored and used to analyze data without any previous biological background. However, analyzing them becomes challenging if data are missing.
Nourhan Yehia, Manal Abdel Wahed, Mai Said Mabrouk   +2 more
doaj   +1 more source

Automating the processing of cDNA microarray images [PDF]

, 2008
This work is concerned with the development of an automatic image processing tool for DNA microarray images. This paper proposes, implements and tests a new tool for cDNA image analysis.
Goulermas, J. Y., Liatsis, P., Milonidis, E., Nazarboland, M. A., Zeng, X. J.   +4 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Recovering Sparse Signals Using Sparse Measurement Matrices in Compressed DNA Microarrays [PDF]

, 2008
Microarrays (DNA, protein, etc.) are massively parallel affinity-based biosensors capable of detecting and quantifying a large number of different genomic particles simultaneously.
Hassibi, Babak, Misra, Sidhant, Parvaresh, Farzad, Vikalo, Haris   +3 more
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Tetrahymena thermophila Functional Genomics Database

中国科学数据, 2022
Tetrahymena thermophila is an excellent unicellular eukaryote. Since T. thermophila could be purely cultured in the lab, well established molecular and genetic techniques and clear genetic ...
Yang Wentao, Wang Guangying, Tian Miao, Yuan Dongxia, Miao Wei, Zeng Honghui, Xiong Jie   +6 more
doaj   +1 more source

Modeling and Estimation for Real-Time Microarrays [PDF]

, 2008
Microarrays are used for collecting information about a large number of different genomic particles simultaneously. Conventional fluorescent-based microarrays acquire data after the hybridization phase.
Hassibi, Arjang, Hassibi, Babak, Vikalo, Haris   +2 more
core   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

The Impact of Photobleaching on Microarray Analysis

Biology, 2015
DNA-Microarrays have become a potent technology for high-throughput analysis of genetic regulation. However, the wide dynamic range of signal intensities of fluorophore-based microarrays exceeds the dynamic range of a single array scan by far, thus ...
Marcel von der Haar, John-Alexander Preuß, Kathrin von der Haar, Patrick Lindner, Thomas Scheper, Frank Stahl   +5 more
doaj   +1 more source