Results 51 to 60 of about 91,462 (268)

Gene set enrichment meta-learning analysis: next- generation sequencing versus microarrays

BMC Bioinformatics, 2010
Background Reproducibility of results can have a significant impact on the acceptance of new technologies in gene expression analysis. With the recent introduction of the so-called next-generation sequencing (NGS) technology and established microarrays ...
Bajgot Mateja, Stiglic Gregor, Kokol Peter   +2 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

DNA microarray technology in medical diagnostics

Zdravniški Vestnik, 2007
Background: DNA microarray technology opened a completely new venue in the biomedical research. By allowing to follow the expression of thousands of genes in a single experiment (ideally we can follow the expression of the entire genome), the microarray ...
Damjana Rozman, Peter Juvan
doaj  

Multiphoton‐Printed Microrobotic Arrays Powered by Discrete, Monolithically Integrated Hydrogel Actuators

Advanced Robotics Research, EarlyView.
Functional surfaces are investigated as a foundation for reconfigurable microscale systems with sensing and actuation capabilities. Advances in additive manufacturing enable our development of planar arrays of hybrid‐material, compliant microdevices that convert environmental stimuli into programmed motion and visual responses.
Sandra Edward, Eric Nieto Gonzalez, Michael Gallegos, Thomas Golecki, Bryan Kaehr, Holly M. Golecki   +5 more
wiley   +1 more source

Robust gene selection methods using weighting schemes for microarray data analysis

BMC Bioinformatics, 2017
Background A common task in microarray data analysis is to identify informative genes that are differentially expressed between two different states. Owing to the high-dimensional nature of microarray data, identification of significant genes has been ...
Suyeon Kang, Jongwoo Song
doaj   +1 more source

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

Advanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia, William Y. Wang, Kyle A. Jacobs, Kairav Maniar, Daphne Lin, Evan H. Jarman, Daniel L. Matera, Kristen Loesel, Christopher D. Davidson, Harrison L. Hiraki, Xiaotian Tan, Eve H. Shikanov, Robert N. Kent, Carole Parent, Xudong Fan, Ariella Shikanov, Matthew L. Kutys, Brendon M. Baker   +17 more
wiley   +1 more source

Triple-target microarray experiments: a novel experimental strategy

BMC Genomics, 2004
Background High-throughput, parallel gene expression analysis by means of microarray technology has become a widely used technique in recent years. There are currently two main dye-labelling strategies for microarray studies based on custom-spotted cDNA ...
Cooke Howard J, Roy Douglas, Costa Yael, Forster Thorsten, Maratou Klio   +4 more
doaj   +1 more source

A Discrete Wavelet Based Feature Extraction and Hybrid Classification Technique for Microarray Data Analysis [PDF]

The Scientific World Journal, 2014
Cancer classification by doctors and radiologists was based on morphological and clinical features and had limited diagnostic ability in olden days. The recent arrival of DNA microarray technology has led to the concurrent monitoring of thousands of gene expressions in a single chip which stimulates the progress in cancer classification. In this paper,
Jaison Bennet, Chilambuchelvan Arul Ganaprakasam, Kannan Arputharaj   +2 more
openaire   +3 more sources

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

Transformation Based Tri-Level Feature Selection Approach Using Wavelets and Swarm Computing for Prostate Cancer Classification

IEEE Access, 2020
Prostate Cancer is a cancer that occurs in the prostate- a small walnut shaped gland in men. This gland helps in the production of seminal fluid which is used to nourish and transport the sperm.
Sunil Kumar Prabhakar, Seong-Whan Lee
doaj   +1 more source