Results 61 to 70 of about 187,728 (325)

Differential meta-analysis of RNA-seq data from multiple studies [PDF]

, 2013
High-throughput sequencing is now regularly used for studies of the transcriptome (RNA-seq), particularly for comparisons among experimental conditions.
Jaffrézic, Florence, Marot, Guillemette, Rau, Andrea   +2 more
core   +9 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Web-based Tools for the Analysis of DNA Microarrays [PDF]

, 2008
End of project reportDNA microarrays are widely used for gene expression profiling. Raw data resulting from microarray experiments, however, tends to be very noisy and there are many sources of technical variation and bias.
Geeleher, P., Golden, A., Hinde, J., Morris, Dermot G.   +3 more
core  

A graph-based representation of Gene Expression profiles in DNA microarrays [PDF]

, 2008
This paper proposes a new and very flexible data model, called gene expression graph (GEG), for genes expression analysis and classification. Three features differentiate GEGs from other available microarray data representation structures: (i) the memory
Benso, Alfredo, Di Carlo, Stefano, Politano, Gianfranco Michele Maria, Sterpone, Luca   +3 more
core   +2 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

A novel neural network approach to cDNA microarray image segmentation [PDF]

, 2013
This is the post-print version of the Article. The official published version can be accessed from the link below. Copyright @ 2013 Elsevier.Microarray technology has become a great source of information for biologists to understand the workings of DNA ...
Adams, Bachar Zineddin, Bajcsy, Bishop, Blekas, Blekas, Bozinov, Bozinov, Buckley, Burt, Demirkaya, Demuth, DeRisi, DeRisi, Eisen, Fausett, Fraser, Fraser, Ham, Haykin, Hebb, Jain, Jie Cao, Jinling Liang, Katzer, Lawrence, Lehmussola, Li, Liao, Lukac, Lukac, Mata, MathWorks, McCulloch, Min Du, Moore, Morris, Nianyin Zeng, Noda, Orengo, Otsu, Schena, Srinark, Tran, Wang, Wang, Whitchurch, Wit, Xiaohui Liu, Yang, Yurong Li, Zidong Wang, Zineddin   +52 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

A Fully Automated Spot Detection Approach for cDNA Microarray Images Using Adaptive Thresholds and Multi-Resolution Analysis

IEEE Access, 2019
The problem of gridding microarray images remains a challenging task. This is because microarray images are usually contaminated with noise and artifacts, such as low intensity and poor quality spots.
Mary Monir Saeid, Zaki B. Nossair, Mohamed Ali Saleh   +2 more
doaj   +1 more source

Pre-implantation Genetic Testing for Aneuploidy (PGT-A)

Thai Journal of Obstetrics and Gynaecology, 2020
Preimplantation genetic diagnosis (PGD) or embryo selection was first performed in 1989 using PCR for gender selection to avoid X-linked recessive disorder. However, there was a misdiagnosis due to allele drop out (ADO). Therefore, fluorescent in situ
Wirawit Piyamongkol
doaj   +1 more source

Stable Feature Selection for Biomarker Discovery [PDF]

, 2010
Feature selection techniques have been used as the workhorse in biomarker discovery applications for a long time. Surprisingly, the stability of feature selection with respect to sampling variations has long been under-considered.
He, Zengyou, Yu, Weichuan
core   +2 more sources