Results 41 to 50 of about 187,728 (325)

Cellular neural networks, Navier-Stokes equation and microarray image reconstruction [PDF]

open access: yes, 2011
Copyright @ 2011 IEEE.Although the last decade has witnessed a great deal of improvements achieved for the microarray technology, many major developments in all the main stages of this technology, including image processing, are still needed.
Liu, X, Wang, Z, Zineddin, B
core   +1 more source

Optimization of Cyanine Dye Stability and Analysis of FRET Interaction on DNA Microarrays

open access: yesBiology, 2016
The application of DNA microarrays for high throughput analysis of genetic regulation is often limited by the fluorophores used as markers. The implementation of multi-scan techniques is limited by the fluorophores’ susceptibility to photobleaching when ...
Marcel von der Haar   +6 more
doaj   +1 more source

Pro-MAP: a robust pipeline for the pre-processing of single channel protein microarray data

open access: yesBMC Bioinformatics, 2022
Background The central role of proteins in diseases has made them increasingly attractive as therapeutic targets and indicators of cellular processes. Protein microarrays are emerging as an important means of characterising protein activity.
Metoboroghene Oluwaseyi Mowoe   +6 more
doaj   +1 more source

Profound effect of profiling platform and normalization strategy on detection of differentially expressed microRNAs [PDF]

open access: yes, 2012
Adequate normalization minimizes the effects of systematic technical variations and is a prerequisite for getting meaningful biological changes. However, there is inconsistency about miRNA normalization performances and recommendations.
Kaiser, Sebastian   +4 more
core   +1 more source

Evaluation of the Tissue Microarray Technique for Immunohistochemical Analysis in Rectal Cancer

open access: yesArchives of Pathology & Laboratory Medicine, 2002
Abstract Background. —Immunohistochemical staining for tumor-associated proteins is widely used for the identification of novel prognostic markers. Recently, a tissue-conserving, high-throughput technique, tissue microarray, has been introduced.
Eva, Fernebro   +4 more
openaire   +2 more sources

Comprehensive Review of Hybrid Feature Selection Methods for Microarray-Based Cancer Detection

open access: yesIEEE Access
Microarray data-based cancer detection advances early diagnosis and personalized medicine by utilizing gene expression data to develop comprehensive cancer profiles, measuring thousands of genes simultaneously.
Azka Khoirunnisa   +3 more
doaj   +1 more source

SMART: Unique splitting-while-merging framework for gene clustering [PDF]

open access: yes, 2014
Copyright @ 2014 Fa et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Thalamuthu   +36 more
core   +3 more sources

Weighted k-Nearest-Neighbor Techniques and Ordinal Classification [PDF]

open access: yes, 2004
In the field of statistical discrimination k-nearest neighbor classification is a well-known, easy and successful method. In this paper we present an extended version of this technique, where the distances of the nearest neighbors can be taken into ...
Hechenbichler, K., Schliep, K.
core   +2 more sources

Application of chromosome microarray analysis and karyotyping in fetal cardiac abnormalities

open access: yesFrontiers in Genetics
ObjectiveChromosome microarray analysis (CMA) and karyotyping are two important genetic testing techniques used in prenatal diagnosis. This study aims to evaluate the value of chromosome microarray analysis and karyotyping in the diagnosis of fetal ...
Yun Guo   +3 more
doaj   +1 more source

Analysis with respect to instrumental variables for the exploration of microarray data structures

open access: yesBMC Bioinformatics, 2006
Background Evaluating the importance of the different sources of variations is essential in microarray data experiments. Complex experimental designs generally include various factors structuring the data which should be taken into account. The objective
Schwager Joseph   +4 more
doaj   +1 more source

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