Results 221 to 230 of about 134,878 (263)
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Immunohistochemistry Microarrays
Analytical Chemistry, 2017Immunohistochemistry (IHC) on tissue sections is widely used for quantifying the expression patterns of proteins and is part of the standard of care for cancer diagnosis and prognosis, but is limited to staining a single protein per tissue. Tissue microarray and microfluidics staining methods have emerged as powerful high throughput techniques, but ...
Huiyan Li +5 more
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Zeitschrift für Rheumatologie, 2011
Since their development in the 1990s DNA microarrays have advanced to one of the most important technologies for biomedical research. Miniaturization enables up to 1 million different sequence-specific DNA hybridization tests to be performed on an area of less than 2 cm². Depending on the selection of oligonucleotide sequences, which are assembled on a
R, Biesen, T, Häupl
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Since their development in the 1990s DNA microarrays have advanced to one of the most important technologies for biomedical research. Miniaturization enables up to 1 million different sequence-specific DNA hybridization tests to be performed on an area of less than 2 cm². Depending on the selection of oligonucleotide sequences, which are assembled on a
R, Biesen, T, Häupl
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Current Protocols in Protein Science, 2005
AbstractWith the introduction of DNA microarrays as novel analytical tools, the determination of thousands of binding events in one reaction became possible. The developed technology platforms are not limited to nucleic acids, and, in principle, every ligand‐binding assay that works on solid phase can be miniaturized and brought into an array format ...
Stefan, Kramer +2 more
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AbstractWith the introduction of DNA microarrays as novel analytical tools, the determination of thousands of binding events in one reaction became possible. The developed technology platforms are not limited to nucleic acids, and, in principle, every ligand‐binding assay that works on solid phase can be miniaturized and brought into an array format ...
Stefan, Kramer +2 more
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Microarrays in Pharmacogenomics
Journal of Biopharmaceutical Statistics, 2004DNA array technology provides tools for studying the expression profiles of a large number of distinct genes simultaneously.
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2008
High throughput methodologies have increased by several orders of magnitude the amount of experimental microarray data available. Nevertheless, translating these data into useful biological knowledge remains a challenge. There is a risk of perceiving these methodologies as mere factories that produce never-ending quantities of data if a proper ...
Dopazo J, Al-Shahrour F
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High throughput methodologies have increased by several orders of magnitude the amount of experimental microarray data available. Nevertheless, translating these data into useful biological knowledge remains a challenge. There is a risk of perceiving these methodologies as mere factories that produce never-ending quantities of data if a proper ...
Dopazo J, Al-Shahrour F
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MCN: The American Journal of Maternal/Child Nursing, 2016
Abstract Over the last half century, knowledge about genetics, genetic testing, and its complexity has flourished. Completion of the Human Genome Project provided a foundation upon which the accuracy of genetics, genomics, and integration of bioinformatics knowledge and testing has grown exponentially. What is lagging, however, are efforts to
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Abstract Over the last half century, knowledge about genetics, genetic testing, and its complexity has flourished. Completion of the Human Genome Project provided a foundation upon which the accuracy of genetics, genomics, and integration of bioinformatics knowledge and testing has grown exponentially. What is lagging, however, are efforts to
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Cold Spring Harbor Protocols, 2019
Most laboratories will choose to order microarrays from a commercial vendor; however, microarray printing is sufficiently straightforward that even small laboratories with extensive microarray needs may find it cost-effective and worth the effort to produce their own microarrays. Printing microarrays requires a spotting robot.
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Most laboratories will choose to order microarrays from a commercial vendor; however, microarray printing is sufficiently straightforward that even small laboratories with extensive microarray needs may find it cost-effective and worth the effort to produce their own microarrays. Printing microarrays requires a spotting robot.
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2010
Bioinformatics has become an increasingly important tool for molecular biologists, especially for the analysis of microarray data. Microarrays can produce vast amounts of information requiring a series of consecutive analyses to render the data interpretable.
Robert P, Loewe, Peter J, Nelson
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Bioinformatics has become an increasingly important tool for molecular biologists, especially for the analysis of microarray data. Microarrays can produce vast amounts of information requiring a series of consecutive analyses to render the data interpretable.
Robert P, Loewe, Peter J, Nelson
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Expert Review of Molecular Diagnostics, 2005
In the postgenomic era, DNA and protein arrays are increasing the speed at which knowledge is gathered on gene expression in cells and tissues. At the same time, researchers realize that a miniaturized and parallelized analysis of whole cells may equally expedite the acquisition of data describing cellular properties and function.
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In the postgenomic era, DNA and protein arrays are increasing the speed at which knowledge is gathered on gene expression in cells and tissues. At the same time, researchers realize that a miniaturized and parallelized analysis of whole cells may equally expedite the acquisition of data describing cellular properties and function.
openaire +2 more sources
Applied Physiology, Nutrition, and Metabolism, 2008
Adaptations that are the result of exercise require a multitude of changes at the level of gene expression. The mechanisms involved in regulating these changes are many, and can occur at various points in the pathways that affect gene expression. The completion of the human genome sequence, along with the genomes of related species, has provided an ...
Carl, Virtanen, Mark, Takahashi
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Adaptations that are the result of exercise require a multitude of changes at the level of gene expression. The mechanisms involved in regulating these changes are many, and can occur at various points in the pathways that affect gene expression. The completion of the human genome sequence, along with the genomes of related species, has provided an ...
Carl, Virtanen, Mark, Takahashi
openaire +2 more sources