Results 181 to 190 of about 112,013 (244)

Bacterial cell envelope components of gut commensals: effects in host-microbe interaction. [PDF]

Ann Med
Vilela Rodrigues T, Lima de Jesus L, Langella P, de Castro Soares S, Jan G, Ariston de Carvalho Azevedo V, Chatel JM.   +6 more
europepmc   +1 more source

Metabolic Regulation of Dimethylsulfoniopropionate Cleavage and Dimethyl Sulfide Production in Halomonas sp. D47

Advanced Science, EarlyView.
Dimethylsulfoniopropionate (DMSP) is a major marine organosulfur compound central to climate‐relevant dimethyl sulfide (DMS) production. In Halomonas sp. D47, DMSP catabolism is revealed to be coordinated by two transcriptional regulators, AcuR and AcuZ, which control gene expression by sensing DMSP and its metabolites.
Li‐Yuan Zheng, Wen‐Xin Jiang, Xiao‐Meng Sun, Li Liu, Zhao‐Jie Teng, Hou‐Qi Wang, Wen‐Jing Zhu, Chang Ge, Qi‐Long Qin, Ning‐Hua Liu, Hai‐Yan Cao, Hui‐Hui Fu, Chun‐Yang Li, Jonathan D. Todd, Xiu‐Lan Chen, Yu‐Zhong Zhang, Peng Wang   +16 more
wiley   +1 more source

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

Advanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong, Chunyuan Zhao, Chengxi Li, Lin Weng, Zehan Ji, Peiqi Li, Jiqiang Lu, Danni Liu, Anni Yu, Tianyi Jiang, Shaokai Huang, Heng Liu, Xiao Chen, Zichun Hua   +13 more
wiley   +1 more source

Plant genomic and microbial interplay in the rhizosphere under salt stress: a review. [PDF]

Front Plant Sci
Ren Y, Yan H, Ma A.
europepmc   +1 more source

Systematic Benchmarking of a Noise‐Tolerant Conductive Hydrogel Electrode for Epidermal Bioelectronics

Advanced Science, EarlyView.
General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen, Ioannis Ziogas, Shirina Alsaedi, Mouza Alshehhi, Shahd Almheiri, Adil Rehman, Khulood Al Shehhi, Hani Saleh, Ahsan Khandoker, Charalampos Pitsalidis, Antoun Khawaja, Anna‐Maria Pappa   +11 more
wiley   +1 more source

Rapid Remodeling of the Human Gut Microbiome in Response to Short‐Term Animal Product Restriction and Associations with Host Molecular Phenotypes

Advanced Science, EarlyView.
A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil, Maria Anezaki, Alexandros Simistiras, Stavros Glentis, Nikolaos Scarmeas, Pantelis Hatzis, Konstantinos Rouskas, Antigone S. Dimas   +7 more
wiley   +1 more source

Gut microbiome-driven colorectal cancer via immune, metabolic, neural, and endocrine axes reprogramming. [PDF]

NPJ Biofilms Microbiomes
Bautista J, Lamas-Maceiras M, Hidalgo-Tinoco C, Guerra-Guerrero A, Betancourt-Velarde A, López-Cortés A.   +5 more
europepmc   +1 more source

The Microbiota Shapes Central Nervous System Myelination in Early Life

Advanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch, Emily G. Knox, Daniel Soong, Thomaz F. S. Bastiaanssen, Kalevi Trontti, Gabriel S. S. Tofani, Sophia Ivaschuk, Michael K. Collins, Donia Arafa, Jatin Nagpal, Iiris Hovatta, David A. Lyons, Gerard Clarke, John F. Cryan   +13 more
wiley   +1 more source

Evolutionary mechanisms underlying bacterial adaptation to the plant environment. [PDF]

FEMS Microbiol Rev
Saati-Santamaría Z, Pérez-Mendoza D, Khashi U Rahman M, de Sousa BFS, Montero-Calasanz MDC, Rey L, Roy S, Sanjuán J, García-Fraile P.   +8 more
europepmc   +1 more source

A Deep Representation Learning Method for Quantitative Immune Defense Function Evaluation and Its Clinical Applications

Advanced Science, EarlyView.
ImmuDef, a novel algorithm to quantitatively evaluate the anti‐infection immune defense function of an individual based on RNA‐seq data via a variational autoencoder (VAE) model. It is validated on 3200+ samples across four immune states with high accuracy. It can serve as a metric for disease severity and prognosis across pathogenic cohorts.
Zhen‐Lin Tan, Tao Luo, Yu Lin, Xiao‐Jun Wu, Wen‐Kang Shen, Jie Chen, Qian Lei, An‐Yuan Guo   +7 more
wiley   +1 more source