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Evolutionary trajectory of pattern recognition receptors in plants [PDF]
Nature Communications, 2023 Cell-surface receptors play pivotal roles in many biological processes, including immunity, development, and reproduction, across diverse organisms. How cell-surface receptors evolve to become specialised in different biological processes remains elusive.
Bruno Pok Man Ngou +4 more
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Pattern recognition receptors and autophagy [PDF]
Frontiers in Immunology, 2014 The immune system senses exogenous threats or endogenous stress through specialized machinery known as pattern recognition receptors (PRRs). These receptors recognize conserved molecular structures and initiate downstream signaling pathways to control ...
Ji Eun eOh, Heung Kyu eLee
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Pattern-recognition receptors in endometriosis: A narrative review [PDF]
Frontiers in Immunology, 2023 Endometriosis is closely associated with ectopic focal inflammation and immunosuppressive microenvironment. Multiple types of pattern recognition receptors (PRRs) are present in the innate immune system, which are able to detect pathogen-associated ...
Bao Guo +7 more
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Immune functions of pattern recognition receptors in Lepidoptera [PDF]
Frontiers in Immunology, 2023 Pattern recognition receptors (PRRs), as the “sensors” in the immune response, play a prominent role in recognizing pathogen-associated molecular patterns (PAMPs) and initiating an effective defense response to pathogens in Lepidoptera.
Lin Zhao +4 more
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Pattern recognition receptors in HIV transmission [PDF]
Frontiers in Immunology, 2012 Dendritic cells (DCs), Langerhans cells (LCs) and macrophages are innate immune cells that reside in genital and intestinal mucosal tissues susceptible to HIV-1 infection.
Teunis B. Geijtenbeek, Annelies eMesman
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Pattern recognition receptors and gastric cancer [PDF]
Frontiers in Immunology, 2014 Chronic inflammation has been associated with an increased risk of several human malignancies, a classic example being gastric cancer (GC). Development of GC is known to result from infection of the gastric mucosa by Helicobacter pylori, which initially ...
Natalia eCastaño-Rodriguez +2 more
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Role of pattern recognition receptors in sensing Mycobacterium tuberculosis [PDF]
Heliyon, 2023 Mycobacterium tuberculosis is one of the major invasive intracellular pathogens causing most deaths by a single infectious agent. The interaction between host immune cells and this pathogen is the focal point of the disease, Tuberculosis.
S.M. Neamul Kabir Zihad +7 more
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Pattern recognition receptors and inflammasome: Now and beyond [PDF]
Molecules and Cells: Pattern recognition receptors (PRRs) are fundamental to the innate immune system, functioning to detect and eliminate invading pathogens by inhibiting their replication and limiting host tissue damage.
SuHyeon Oh, Young Ki Choi, SangJoon Lee
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Are Pattern Recognition Receptors Associated with Hepatocellular Carcinoma? [PDF]
The Turkish Journal of Gastroenterology, 2021 Background: Hepatocellular carcinoma (HCC) is one of the important causes of mortality due to malignancy. Toll-like receptors (TLRs) are very important in liver pathophysiology in terms of their roles in the innate immune system, such as the regulation ...
Ramazan Dertli +7 more
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Pattern recognition receptors: function, regulation and therapeutic potential [PDF]
Signal Transduction and Targeted TherapyPattern recognition receptors (PRRs) are sensors in the immune system, detecting pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs).
Ruochan Chen +5 more
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