Results 31 to 40 of about 401,379 (287)

Comparative genome analysis reveals an absence of leucine-rich repeat pattern-recognition receptor proteins in the kingdom Fungi.

PLoS ONE, 2010
BackgroundIn plants and animals innate immunity is the first line of defence against attack by microbial pathogens. Specific molecular features of bacteria and fungi are recognised by pattern recognition receptors that have extracellular domains ...
Darren M Soanes, Nicholas J Talbot
doaj   +1 more source

Identification of CNS Injury-Related microRNAs as Novel Toll-Like Receptor 7/8 Signaling Activators by Small RNA Sequencing [PDF]

, 2020
Toll-like receptors (TLRs) belong to pattern recognition receptors, which respond to danger signals such as pathogen-associated molecular patterns or damage-associated molecular patterns.
Buonfiglioli, Alice, Dembny, Paul, Krüger, Christina, Lehnardt, Seija, Prinz, Marco, Staszewski, Ori, Wallach, Thomas, Wetzel, Max   +7 more
core   +1 more source

Macrophages disseminate pathogen associated molecular patterns through the direct extracellular release of the soluble content of their phagolysosomes

Nature Communications, 2022
The detection of conserved motifs by pattern recognition receptors is a crucial component of the innate detection of pathogens and danger signals via conserved pattern recognition receptors.
Catherine J. Greene, Jenny A. Nguyen, Samuel M. Cheung, Corey R. Arnold, Dale R. Balce, Ya Ting Wang, Adrian Soderholm, Neil McKenna, Devin Aggarwal, Rhiannon I. Campden, Benjamin W. Ewanchuk, Herbert W. Virgin, Robin M. Yates   +12 more
doaj   +1 more source

Domain architecture evolution of pattern-recognition receptors [PDF]

, 2010
In animals, the innate immune system is the first line of defense against invading microorganisms, and the pattern-recognition receptors (PRRs) are the key components of this system, detecting microbial invasion and initiating innate immune defenses. Two
Qing Zhang, Christian M. Zmasek, Adam Godzik, SF Altschul, G Apic, NA Baker, MK Basu, A Bateman, B Beutler, TA Binkowski, AK Bjorklund, D Boraschi, CB Burge, AA Canutescu, RR Copley, JA Darling, R Desper, M Dlugosz, CB Do, SR Eddy, J Felsenstein, K Forslund, JH Fritz, O Gascuel, J Gough, JH Han, T Hibino, AL Hughes, AL Hughes, A Ishii, Z Kambris, TD Kanneganti, K Katoh, KJ Laing, O Lespinet, F Leulier, A Marchler-Bauer, A Marchler-Bauer, F Martinon, AF McGettrick, R Medzhitov, PA Nuin, LA O'Neill, H Oshiumi, L Patthy, K Pawlowski, NH Putnam, NH Putnam, H Qin, AJ Robertson, F Ronquist, L Sael, N Saitou, JM Sasin, HA Schmidt, E Sodergren, A Stamatakis, C Stein, JP Ting, J Weiner 3rd, AP West, MJ West-Eberhard, Q Zhang   +62 more
core   +2 more sources

Interaction between Cannabinoid System and Toll-Like Receptors Controls Inflammation [PDF]

, 2016
Since the discovery of the endocannabinoid system consisting of cannabinoid receptors, endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been renewed in investigating the promise of cannabinoids as therapeutic agents.
McCoy, Kathleen L.
core   +4 more sources

Pattern recognition receptors in microbial keratitis [PDF]

Eye, 2015
Microbial keratitis is a significant cause of global visual impairment and blindness. Corneal infection can be caused by a wide variety of pathogens, each of which exhibits a range of mechanisms by which the immune system is activated. The complexity of the immune response to corneal infection is only now beginning to be elucidated.
Taube, M.A., Del Mar Cendra, M., Elsahn, A., Christodoulides, Myron, Hossain, Parwez   +4 more
openaire   +3 more sources

Recognition of human oncogenic viruses by host pattern recognition receptors

Frontiers in Immunology, 2014
Human oncogenic viruses include Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C virus (HCV), human papilloma virus (HPV), human T-cell lymphotropic virus (HTLV-1), Kaposi’s associated sarcoma virus (KSHV), and Merkel cell polyomavirus ...
Nelson C Di Paolo
doaj   +1 more source

Genotyping-by-sequencing-based identification of Arabidopsis pattern recognition receptor RLP32 recognizing proteobacterial translation initiation factor IF1

Nature Communications, 2022
Pattern-triggered immunity is activated by recognition of microbe-derived structures by host pattern recognition receptors. Here the authors use a genotype-by sequencing approach to show that bacterial translation initiation factor 1 triggers PTI in ...
Li Fan, Katja Fröhlich, Eric Melzer, Rory N. Pruitt, Isabell Albert, Lisha Zhang, Anna Joe, Chenlei Hua, Yanyue Song, Markus Albert, Sang-Tae Kim, Detlef Weigel, Cyril Zipfel, Eunyoung Chae, Andrea A. Gust, Thorsten Nürnberger   +15 more
doaj   +1 more source

Inflammation-induced DNA damage and damage-induced inflammation: a vicious cycle [PDF]

, 2014
Inflammation is the ultimate response to the constant challenges of the immune system by microbes, irritants or injury. The inflammatory cascade initiates with the recognition of microorganism-derived pathogen associated molecular patterns (PAMPs) and ...
Abe, Alexeyev, Andersson, Andersson, Ba, Babior, Bartoloni, Berger, Blyth, Brill, Brinkmann, Cadet, Collins, Cooke, Csanád Z. Bachrati, David, Ding, Dostert, Ermakov, Ermakov, Ferguson, Fuchs, Gahan, Gedik, Gehrke, Hajizadeh, Halle, Hiramoto, Huang, Huang, Huang, Huttunen, Ishikawa, Ivana, Ivanov, Jahr, Jia, Kang, Kanneganti, Kazak, Klebanoff, Knaapen, Kondo, Kostyuk, Kostyuk, Krieg, Kuechle, Lane, Lange, Latz, Li, Malins, Mariathasan, Munoz-Gamez, Nakahira, Oka, Pacher, Parvatiyar, Pasheva, Pinti, Polk, Rathinam, Saitoh, Saxena, Scaffidi, Schroder, Shimada, Shokolenko, Sun, Suter, Suzuki, Swindall, Tadie, Taguchi, Takeda, Takeda, Tang, Tang, Thomson, Timea Pálmai-Pallag, Unterholzner, Urbonaviciute, Venereau, Volcic, Weinberg, Weiss, Wilson, Wu, Yan, Yang, Yoshida, Yoshihara, Yotsumoto, You, Yousefi, Zhang, Zhang, Zhang, Zhang, Zhang, Zhou   +100 more
core   +1 more source

Intracellular pattern-recognition receptors☆

Advanced Drug Delivery Reviews, 2008
The last ten years of research in the field of innate immunity have been incredibly fertile: the transmembrane Toll-like receptors (TLRs) were discovered as guardians protecting the host against microbial attacks and the emerging pathways characterized in detail.
DOSTERT, C, Meylan, Etienne, Tschopp, J
openaire   +4 more sources