Results 11 to 20 of about 3,901,299 (285)
Inhibitory pattern recognition receptors [PDF]
Journal of Experimental Medicine, 2022 Pathogen- and damage-associated molecular patterns are sensed by the immune system’s pattern recognition receptors (PRRs) upon contact with a microbe or damaged tissue. In situations such as contact with commensals or during physiological cell death, the immune system should not respond to these patterns.
Helen J von Richthofen +2 more
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Pattern recognition receptors and autophagy [PDF]
Frontiers in Immunology, 2014 The immune system senses exogenous threats or endogenous stress through specialized machinery known as pattern recognition receptors (PRRs). These receptors recognize conserved molecular structures and initiate downstream signaling pathways to control ...
Ji Eun eOh, Heung Kyu eLee
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Pattern recognition receptors in HIV transmission [PDF]
Frontiers in Immunology, 2012 Dendritic cells (DCs), Langerhans cells (LCs) and macrophages are innate immune cells that reside in genital and intestinal mucosal tissues susceptible to HIV-1 infection.
Teunis B. Geijtenbeek, Annelies eMesman
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Pattern recognition receptors in health and diseases [PDF]
Signal Transduction and Targeted Therapy, 2021 Pattern recognition receptors (PRRs) are a class of receptors that can directly recognize the specific molecular structures on the surface of pathogens, apoptotic host cells, and damaged senescent cells.
Danyang Li, Minghua Wu
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Inherited variation in pattern recognition receptors and cancer: dangerous liaisons?
Cancer Management and Research, 2012 Anton G Kutikhin, Arseniy E YuzhalinDepartment of Epidemiology, Kemerovo State Medical Academy, Kemerovo, Russian FederationAbstract: The group of pattern recognition receptors includes families of Toll-like receptors, NOD-like receptors, C-type lectin ...
Yuzhalin AE, Kutikhin AG
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Pattern recognition receptors in Crustacea: immunological roles under environmental stress [PDF]
Frontiers in ImmunologyInnate immunity is the first line of defense against infections and the only known available strategy for invertebrates. Crustaceans, being mostly aquatic invertebrates, are constantly exposed to potential pathogens in the surrounding water. Their immune
Jesús Luis Betancourt +2 more
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Editorial: Pattern-recognition receptors: Genetics, immunity, pathology [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 Petro Starokadomskyy
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cGLRs are a diverse family of pattern recognition receptors in innate immunity [PDF]
Cell, 2023 Philip J Kranzusch
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Pattern recognition receptors as a double-edged sword in cancer
Frontiers in Immunology, 2015 The problem of cancer remains one of the most immense challenges to current biomedical research. Affecting populations in all countries and all regions, this disease is responsible for millions of deaths annually (1). Evasion of the immune system is an ominous feature of cancers, which often leads to tumor outgrowth, epithelial–mesenchymal transition ...
Anton G. Kutikhin, Arseniy E Yuzhalin
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Identifying the Patterns of Pattern Recognition Receptors [PDF]
Immunity, 2018 Intestinal homeostasis requires microbial recognition that results in appropriate responses to commensals and pathogens. In this issue of Immunity, Price et al. (2018) map the in vivo expression of five toll-like receptors (TLR) in intestinal epithelia, revealing distinct spatio-temporal expression patterns that shape responses to TLR ligands.
Andrea A, Hill, Gretchen E, Diehl
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