Results 21 to 30 of about 683,305 (299)

Genomic analysis on broiler-associated Clostridium perfringens strains and exploratory caecal microbiome investigation reveals key factors linked to poultry necrotic enteritis

open access: yesAnimal Microbiome, 2019
Background Clostridium perfringens is a key pathogen in poultry-associated necrotic enteritis (NE). To date there are limited Whole Genome Sequencing based studies describing broiler-associated C. perfringens in healthy and diseased birds.
Raymond Kiu   +8 more
doaj   +1 more source

Producing polished prokaryotic pangenomes with the Panaroo pipeline

open access: yesGenome Biology, 2020
Population-level comparisons of prokaryotic genomes must take into account the substantial differences in gene content resulting from horizontal gene transfer, gene duplication and gene loss.
Gerry Tonkin-Hill   +13 more
doaj   +1 more source

Interplay between host-microbe and microbe-microbe interactions in cystic fibrosis

open access: yesJournal of Cystic Fibrosis, 2020
The respiratory tract of individuals with cystic fibrosis is host to polymicrobial infections that persist for decades and lead to significant morbidity and mortality. Improving our understanding of CF respiratory infections requires coordinated efforts from researchers in the fields of microbial physiology, genomics, and ecology, as well as epithelial
Catherine R. Armbruster   +3 more
openaire   +3 more sources

Comparison of PCR versus PCR-Free DNA Library Preparation for Characterising the Human Faecal Virome

open access: yesViruses, 2021
The human intestinal microbiota is abundant in viruses, comprising mainly bacteriophages, occasionally outnumbering bacteria 10:1 and is termed the virome.
Shen-Yuan Hsieh   +9 more
doaj   +1 more source

GeneDB and Wikidata [version 2; peer review: 2 approved]

open access: yesWellcome Open Research, 2019
Publishing authoritative genomic annotation data, keeping it up to date, linking it to related information, and allowing community annotation is difficult and hard to support with limited resources. Here, we show how importing GeneDB annotation data into
Magnus Manske   +3 more
doaj   +1 more source

A Tangled Threesome: Circadian Rhythm, Body Temperature Variations, and the Immune System

open access: yesBiology, 2021
The circadian rhythm of the body temperature (CRBT) is a marker of the central biological clock that results from multiple complex biological processes.
Benjamin Coiffard   +4 more
doaj   +1 more source

A molecular perspective on the limits of life: Enzymes under pressure [PDF]

open access: yes, 2016
From a purely operational standpoint, the existence of microbes that can grow under extreme conditions, or "extremophiles", leads to the question of how the molecules making up these microbes can maintain both their structure and function. While microbes
Bartlett, D. H.   +5 more
core   +2 more sources

Microbe Hunting [PDF]

open access: yesMicrobiology and Molecular Biology Reviews, 2010
SUMMARY Platforms for pathogen discovery have improved since the days of Koch and Pasteur; nonetheless, the challenges of proving causation are at least as daunting as they were in the late 1800s. Although we will almost certainly continue to accumulate low-hanging fruit, where simple relationships will be found between the ...
openaire   +2 more sources

Microbe–microbe interactions during Clostridioides difficile infection

open access: yesCurrent Opinion in Microbiology, 2020
Clostridioides difficile is the leading cause of hospital-acquired gastrointestinal infections and a major public health burden in the United States. C. difficile infection causes a spectrum of disease from mild diarrhea to severe complications such as pseudomembranous colitis, toxic megacolon and death.
Arwa Abbas, Joseph P Zackular
openaire   +3 more sources

Prediction and prevention of the next pandemic zoonosis. [PDF]

open access: yes, 2012
Most pandemics--eg, HIV/AIDS, severe acute respiratory syndrome, pandemic influenza--originate in animals, are caused by viruses, and are driven to emerge by ecological, behavioural, or socioeconomic changes.
Carroll, Dennis   +8 more
core   +1 more source

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