Results 21 to 30 of about 302,021 (264)

Genomic analysis of a rare recurrent Listeria monocytogenes prosthetic joint infection indicates a protected niche within biofilm on prosthetic materials

Scientific Reports, 2021
Listeria monocytogenes is a rare cause of prosthetic joint infections (PJI). In this study, we describe a case of recurrent L. monocytogenes infections, 39 months apart, following debridement and retention of a prosthetic hip.
Chloe Hutchins, Lizbeth Sayavedra, Maria Diaz, Puja Gupta, Elizabeth Tissingh, Chiamaka Elumogo, John Nolan, Ian Charles, Ngozi Elumogo, Arjan Narbad   +9 more
doaj   +1 more source

A Tangled Threesome: Circadian Rhythm, Body Temperature Variations, and the Immune System

Biology, 2021
The circadian rhythm of the body temperature (CRBT) is a marker of the central biological clock that results from multiple complex biological processes.
Benjamin Coiffard, Aïssatou Bailo Diallo, Soraya Mezouar, Marc Leone, Jean-Louis Mege   +4 more
doaj   +1 more source

Comparison of PCR versus PCR-Free DNA Library Preparation for Characterising the Human Faecal Virome

Viruses, 2021
The human intestinal microbiota is abundant in viruses, comprising mainly bacteriophages, occasionally outnumbering bacteria 10:1 and is termed the virome.
Shen-Yuan Hsieh, Mohammad A. Tariq, Andrea Telatin, Rebecca Ansorge, Evelien M. Adriaenssens, George M. Savva, Catherine Booth, Tom Wileman, Lesley Hoyles, Simon R. Carding   +9 more
doaj   +1 more source

Editorial – Fighting microbes with microbes

Microbiota in Health and Disease, 2022
[No Abstract available]
Franceschi, F., Megraud, F.
openaire   +1 more source

The Cynomolgus Macaque Intestinal Mycobiome Is Dominated by the Kazachstania Genus and K. pintolopesii Species

Journal of Fungi, 2022
The cynomolgus macaque, Macaca fascicularis, is a non-human primate (NHP) widely used in biomedical research as its genetics, immunology and physiology are similar to those of humans.
Steve A. James, Aimee Parker, Catherine Purse, Andrea Telatin, David Baker, Sandy Holmes, James Durham, Simon G. P. Funnell, Simon R. Carding   +8 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Development of a novel human intestinal model to elucidate the effect of anaerobic commensals on Escherichia coli infection

Disease Models & Mechanisms, 2022
The gut microbiota plays a crucial role in protecting against enteric infection. However, the underlying mechanisms are largely unknown owing to a lack of suitable experimental models.
Conor J. McGrath, Edgaras Laveckis, Andrew Bell, Emmanuelle Crost, Nathalie Juge, Stephanie Schüller   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

High quality transcriptome profiling confirms the transcriptional landscape of Treponema pallidum subsp. pallidum

Scientific Reports
Syphilis remains a critical global health challenge due to its potential for severe complications and the increase in its incidence rate over recent years. Until recently, the infectious agent of syphilis, Treponema pallidum subsp.
Linda Grillová, Eli M. Carrami, William Roberts-Sengier, Nicholas R. Thomson   +3 more
doaj   +1 more source

Prioritizing precision: guidelines for the better use of population descriptors in human microbiome research

mSystems
Microbiome science is a celebration of the connections between humans, our environment, and microbial organisms. We are continually learning more about our microbial fingerprint, how each microbiome may respond to identical stimuli differently, and how ...
Nicole M. Farmer, Amber Benezra, Katherine A. Maki, Suzanne L. Ishaq, Ariangela J. Kozik   +4 more
doaj   +1 more source