Results 41 to 50 of about 683,305 (299)

High quality transcriptome profiling confirms the transcriptional landscape of Treponema pallidum subsp. pallidum

Scientific Reports
Syphilis remains a critical global health challenge due to its potential for severe complications and the increase in its incidence rate over recent years. Until recently, the infectious agent of syphilis, Treponema pallidum subsp.
Linda Grillová, Eli M. Carrami, William Roberts-Sengier, Nicholas R. Thomson   +3 more
doaj   +1 more source

Prioritizing precision: guidelines for the better use of population descriptors in human microbiome research

mSystems
Microbiome science is a celebration of the connections between humans, our environment, and microbial organisms. We are continually learning more about our microbial fingerprint, how each microbiome may respond to identical stimuli differently, and how ...
Nicole M. Farmer, Amber Benezra, Katherine A. Maki, Suzanne L. Ishaq, Ariangela J. Kozik   +4 more
doaj   +1 more source

Ecological and Genomic Attributes of Novel Bacterial Taxa That Thrive in Subsurface Soil Horizons. [PDF]

, 2019
While most bacterial and archaeal taxa living in surface soils remain undescribed, this problem is exacerbated in deeper soils, owing to the unique oligotrophic conditions found in the subsurface.
Arogyaswamy, Keshav, Aronson, Emma L, Billings, Sharon A, Botthoff, Jon K, Brewer, Tess E, Campbell, Ashley N, Dove, Nicholas C, Fairbanks, Dawson, Fierer, Noah, Gallery, Rachel E, Hart, Stephen C, Kaye, Jason, King, Gary, Logan, Geoffrey, Lohse, Kathleen A, Maltz, Mia R, Mayorga, Emilio, O'Neill, Caitlin, Owens, Sarah M, Packman, Aaron, Pett-Ridge, Jennifer, Plante, Alain F, Richter, Daniel D, Silver, Whendee L, Yang, Wendy H   +24 more
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Genomic, proteomic and bioinformatic analysis of two temperate phages in Roseobacter clade bacteria isolated from the deep-sea water

BMC Genomics, 2017
Background Marine phages are spectacularly diverse in nature. Dozens of roseophages infecting members of Roseobacter clade bacteria were isolated and characterized, exhibiting a very high degree of genetic diversity.
Kai Tang, Dan Lin, Qiang Zheng, Keshao Liu, Yujie Yang, Yu Han, Nianzhi Jiao   +6 more
doaj   +1 more source

House Flies: Manure, Media, and Microbes [PDF]

, 2018
This study was conducted to determine if there is a difference in bacterial abundance in house flies based on sex and rearing environment (manure versus artificial media) for house flies.
Adams, Porter, McCoy, Christie, Nayduch, Dana, Thomson, Jessica L.   +3 more
core  

Incorporating a mucosal environment in a dynamic gut model results in a more representative colonization by lactobacilli [PDF]

, 2011
To avoid detrimental interactions with intestinal microbes, the human epithelium is covered with a protective mucus layer that traps host defence molecules. Microbial properties such as adhesion to mucus further result in a unique mucosal microbiota with
Derde, Melanie, Eeckhaut, Venessa, MacKenzie, Donald A, Marzorati, Massimo, Possemiers, Sam, Roos, Stefaan, Van de Wiele, Tom, Van den Abbeele, Pieter, Van Immerseel, Filip, Vanhoecke, Barbara, Verstraete, Willy   +10 more
core   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Usurpativirus massiliensis, a new giant virus related to clandestinovirus

Virology Journal
Giant virus discovery in 2003 revolutionized the virus paradigm. In 2015, we introduced a new host, Vermamoeba vermiformis, that led to the discovery of Faustovirus, Orpheovirus and two giant viruses (Clandestinovirus and a faustovirus) having distinct ...
Julien Andreani, Jean-Pierre Baudoin, Léana Laumier, Lucile Pinault, Alice Chanteloup, Philippe Colson, Bernard La Scola   +6 more
doaj   +1 more source

Methanobrevibacter oralis: a comprehensive review

Journal of Oral Microbiology
Methanobrevibacter oralis (M. oralis) has predominated human oral microbiota methanogenic archaea as far back as the Palaeolithic era in Neanderthal populations and gained dominance from the 18th century onwards. M.
Virginie Pilliol, Boualam Mahmoud Abdelwadoud, Hamieh Aïcha, Tellissi Lucille, Aboudharam Gérard, Tassery Hervé, Drancourt Michel, Grine Ghiles, Terrer Elodie   +8 more
doaj   +1 more source