Results 31 to 40 of about 604,459 (219)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Optimization of Biodegradation of Common Bean Biomass for Fermentation Using Trichoderma asperellum WNZ-21 and Artificial Neural Networks

Fermentation
This study showcases a promising approach to sustainably unlocking plant biomass residues by combining biodegradation with artificial intelligence to optimize the process.
Salma Saleh Alrdahe, Zeiad Moussa, Yasmene F. Alanazi, Haifa Alrdahi, WesamEldin I. A. Saber, Doaa Bahaa Eldin Darwish   +5 more
doaj   +1 more source

Soil biological quantity and quality parameters of grasslands in various landscape zones

Plant, Soil and Environment, 2011
In three landscape zones of a permanent grassland catchment (discharge zone, D; transient zone, T; and recharge zone, R; Crystallinicum, Czech Republic), soil moisture by volume (θ) and soil biological quantity and quality parameters, e.g.
R. Duffková, H. Macurová
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The impact of windthrow and fire disturbances on selected soil properties in the Tatra National Park

Soil and Water Research, 2008
: In November 2004, forest stands in the Tatra National Park (TANAP) were affected by windthrow and in July 2005, the wildfire broke out on a part of the affected area.
Erika Gömöryová, Katarína Střelcová, Jaroslav Škvarenina, Juraj Bebej, Dušan Gömöry   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Data resource profile: Exercise habits, step counts, and sedentary behavior from the National Health and Nutrition Survey in Japan

Data in Brief
The National Health and Nutrition Survey consistently assesses the prevalence of exercise habits, step counts, and sedentary behaviors in a strategically selected random sample of the Japanese population.
Takashi Nakagata, Rei Ono
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Atributos químicos e microbianos de solos sob diferentes coberturas vegetais no norte do Estado do Rio de Janeiro Chemical and microbial attributes of soils under different soil covers in Northern Rio de Janeiro State, Brazil

Revista Brasileira de Ciência do Solo, 2008
Os objetivos do presente estudo foram avaliar a influência de Acacia auriculiformis (acácia), Mimosa caesalpiniifolia (sabiá) e Corymbia citriodora (eucalipto), comparadas às coberturas de capoeira e pastagem, sobre os atributos químicos e microbianos do
Emanuela Forestieri da Gama-Rodrigues, Antonio Carlos da Gama-Rodrigues, Gleicia Miranda Paulino, Avilio Antonio Franco   +3 more
doaj   +1 more source