Results 41 to 50 of about 575,799 (266)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Data resource profile: Exercise habits, step counts, and sedentary behavior from the National Health and Nutrition Survey in Japan

open access: yesData in Brief
The National Health and Nutrition Survey consistently assesses the prevalence of exercise habits, step counts, and sedentary behaviors in a strategically selected random sample of the Japanese population.
Takashi Nakagata, Rei Ono
doaj   +1 more source

Microbial diversity and microbial activity in the rhizosphere

open access: yesCiencia del Suelo, 2007
It is well established that microbial life only occupies a minor volume of soil being localised in hot spots such as the rhizosphere soil (Nannipieri et al., 2003), where microflora has a continuous access to a flow of low and high molecular weight organic substrates derived from roots.
Nannipieri P.   +6 more
openaire   +3 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Atributos químicos e microbianos de solos sob diferentes coberturas vegetais no norte do Estado do Rio de Janeiro Chemical and microbial attributes of soils under different soil covers in Northern Rio de Janeiro State, Brazil

open access: yesRevista Brasileira de Ciência do Solo, 2008
Os objetivos do presente estudo foram avaliar a influência de Acacia auriculiformis (acácia), Mimosa caesalpiniifolia (sabiá) e Corymbia citriodora (eucalipto), comparadas às coberturas de capoeira e pastagem, sobre os atributos químicos e microbianos do
Emanuela Forestieri da Gama-Rodrigues   +3 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Plant-associated halotolerant bacteria improving growth of Vicia faba L. Mariout-2 under salinity conditions

open access: yesScientific Reports
In this comprehensive investigation, we successfully isolated and characterized 40 distinct plant-associated halotolerant bacteria strains obtained from three halophytic plant species: Tamarix nilotica, Suaeda pruinosa, and Arthrocnemum macrostachyum ...
Dalia Wael   +3 more
doaj   +1 more source

Oil pollutants in alluvial sediments: Influence of the intensity of contact with ground waters on the effect of microorganisms [PDF]

open access: yesJournal of the Serbian Chemical Society, 2003
The influence of the intensity of interaction between oil pollutants and ground waters in alluvial sediments on the effect of microbial activity was investigated in this work.
Šolević Tatjana M.   +3 more
doaj   +1 more source

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