Results 41 to 50 of about 1,143,420 (310)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Microbial and metabolic succession on common building materials under high humidity conditions. [PDF]

, 2019
Despite considerable efforts to characterize the microbial ecology of the built environment, the metabolic mechanisms underpinning microbial colonization and successional dynamics remain unclear, particularly at high moisture conditions. Here, we applied
Cardona, Cesar, Gao, Peng, Gilbert, Jack A, Goodney, Gabriel, Gottel, Neil, Hartmann, Erica M, Henry, Chris, Kelley, Scott T, Lax, Simon, Stephens, Brent, Thomas, Paul M, Winton, Valerie J, Zhao, Dan   +12 more
core   +3 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Relating Anaerobic Digestion Microbial Community and Process Function [PDF]

, 2016
Anaerobic digestion (AD) involves a consortium of microorganisms that convert substrates into biogas containing methane for renewable energy. The technology has suffered from the perception of being periodically unstable due to limited understanding of ...
Bocher, Benjamin T.W., Maki, James, Venkiteshwaran, Kaushik, Zitomer, Daniel   +3 more
core   +3 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Endophytic Trichoderma asperellum WNZ-21 produces novel bioactives with anticancer, anti-inflammatory, and hemoprotective properties from fermented bean biomass

Frontiers in Microbiology
The increasing demand for novel bioactive compounds is driving research into natural sources, particularly through the valorization of agricultural residues.
Yasmene F. Alanazi, Salma Saleh Alrdahe, Zeiad Moussa, Doaa Bahaa Eldin Darwish, Haifa Alrdahi, WesamEldin I. A. Saber   +5 more
doaj   +1 more source

Remediation of cadmium-tolerant bacteria combined with plant absorption on soil heavy metal cadmium pollution

浙江大学学报. 农业与生命科学版, 2017
Heavy metal contaminants enter the environment through various means, causing heavy metal pollution in the soil, especially heavy metals in farmland soils, which are becoming increasingly serious.
ZHOU Huifang, WANG Jingwen, SUN Jilin, LI Dan, ZHANG Qichun   +4 more
doaj   +1 more source

Active Microbial Sulfur Disproportionation in the Mesoproterozoic [PDF]

Science, 2005
The environmental expression of sulfur compound disproportionation has been placed between 640 and 1050 million years ago (Ma) and linked to increases in atmospheric oxygen. These arguments have their basis in temporal changes in the magnitude of 34 S/ 32 S fractionations between sulfate and ...
Johnston, David Thomas, Wing, Boswell A., Farquhar, James, Kaufman, Alan J., Strauss, Harold, Lyons, Timothy W., Kah, Linda C., Canfield, Donald Eugene   +7 more
openaire   +3 more sources

Effect of zooplankton-mediated trophic cascades on marine microbial food web components (bacteria, nanoflagellates, ciliates) [PDF]

, 2009
To examine the grazing effects of copepod-dominated mesozooplankton on heterotrophic microbial communities, four mesocosm experiments using gradients of zooplankton abundance were carried out at a coastal marine site.
Hoppe, Hans-Georg, Jürgens, K., Sommer, Ulrich, Zöllner, Eckart   +3 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source