Results 61 to 70 of about 29,219 (208)

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

Advanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen, Hao Shi, Junxian He, Ziyu Liu, Yuanyuan Zhu, Xiaoyan Liang, Guihua Liu, Xing Yang   +7 more
wiley   +1 more source

Periodontitis Induces B Cell‐Macrophage Crosstalk to Exacerbate Glucose Dysregulation in Obesity

Advanced Science, EarlyView.
In obesity, periodontitis exacerbates hyperglycemia and exhibits a liver‐centric preference for glucose regulation. This occurs through a periodontitis‐driven circuit between pathogenic B cells and hepatic macrophages. Their reciprocal expansion, orchestrated by the NLRP3/IL‐18 signaling pathway, amplifies metabolic inflammation and disrupts glucose ...
Wen‐Zhen Lin, Lu‐Jun Zhou, Hui‐Lin Ye, Ting Liu, Bo‐Yan Chen, Xue‐Bing Bai, Jun Zhang, Lan Bai, Lin‐Juan Du, Yuan Liu, Yong‐Li Wang, Hong Zhu, Yu‐Lin Li, Shuo Xu, Xiao‐Qian Meng, Guo‐Cai Tian, Yan Liu, Wu‐Chang Zhang, Ya‐Qin Zhu, Sheng‐Zhong Duan   +19 more
wiley   +1 more source

Seawater Temperature at Harvest Shapes Fillet Proteolytic Activity at Chilled Storage in Three Mediterranean-Farmed Fish

Aquaculture Journal
Fish is highly prone to spoilage due to a combination of intrinsic biochemical processes and microbial proliferation, which together drive rapid quality deterioration during post-harvest handling and storage.
Rafael Angelakopoulos, Alexia E. Fytsili, Arkadios Dimitroglou, Leonidas Papaharisis, Katerina A. Moutou   +4 more
doaj   +1 more source

Detection and diversity of a putative novel heterogeneous polymorphic proline-glycine repeat (Pgr) protein in the footrot pathogen Dichelobacter nodosus [PDF]

, 2010
Dichelobacter nodosus, a Gram-negative anaerobic bacterium, is the essential causative agent of footrot in sheep. Currently, depending on the clinical presentation in the field, footrot is described as benign or virulent; D.
Atiya Ul-Hassan, Buller, Bzymek, Cheetham, Claire L. Russell, Claxton, Depiazzi, Elizabeth M.H. Wellington, Girard, Graham F. Medley, Gravekamp, Gravekamp, Heise, Hindmarsh, Jasmeet Kaler, Jelinek, Jordan, Julian I. Rood, Katz, Katz, Kay, Kennan, Kennan, La Fontaine, Ladefoged, Laura E. Green, Leo A. Calvo-Bado, Lukomski, Madoff, Moore, Myers, Nallapareddy, Nicky Buller, O’Dushlaine, Palmer, Paterson, Pringle, Puopolo, Rasmussen, Romero, Rood, Rose Grogono-Thomas, Ruth M. Kennan, Vanhoof, Verstrepen, Williamson, Yong, Zhang   +47 more
core   +4 more sources

Sensory Nerve‐Derived CGRP Controls Osteoclastogenesis by Limiting Macrophage Bioenergetics in Bone Repair

Advanced Science, EarlyView.
Sensory nerves help bones heal. This study shows that the neuropeptide CGRP, released from sensory nerves, slows down macrophage energy production, preventing excessive bone breakdown. By revealing this nerve–immune–metabolism connection, the work provides new insight into how the body balances bone repair and opens doors to targeted treatments ...
Jiaying Liu, Ting Zhang, Yuqing Mu, Lili Li, Ju Jin, Kevin J Dudley, Wendong Gao, Donglin Cai, Fuhua Yan, Lan Xiao, Yin Xiao   +10 more
wiley   +1 more source

Vacuum Therapy of Diabetic Soft Tissue Wounds: the Impact on the Matrix Metalloproteinase Activity

Mìžnarodnij Endokrinologìčnij Žurnal, 2016
The objective was to investigate the effect of vacuum therapy on the main stages of the healing of purulent wounds of soft tissues in patients with diabetes mellitus, the degree of microbial contamination of wounds and the activity of matrix ...
O.M. Petrenko, B.H. Bezrodnyi, A.O. Tykhomyrov   +2 more
doaj   +1 more source

Association between malaria exposure and Kaposi's sarcoma-associated herpes virus seropositivity in Uganda. [PDF]

, 2015
OBJECTIVE: Unlike other herpes viruses, Kaposi's sarcoma-associated herpes virus (KSHV) is not ubiquitous worldwide and is most prevalent in sub-Saharan Africa. The reasons for this are unclear. As part of a wider investigation of factors that facilitate
Cose, Stephen, Drakeley, Christopher, Elliott, Alison, Miley, Wendell, Nalwoga, Angela, Ndibazza, Juliet, Newton, Robert, Wakeham, Katie, Whitby, Denise   +8 more
core   +2 more sources

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

Advanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou, Yao Xiao, Ziyue Xu, Chengyu Yang, Jiang Li, Ya Liu, Ping Yin   +6 more
wiley   +1 more source

Formulation and evaluation of spirulina, red algae, and jack fruit seed powders infused anti-aging cream: In Silico analysis and physiochemical characteristics

Food Chemistry Advances
The present work aims to formulate a non-toxic, 100 % natural anti-aging cream with the combination of red algae, green algae, and Jack fruit seed for the first time. The Gas chromatography and Mass spectrometry (GC–MS) analysis of green algae, red algae,
Soundarya Balasubramanian, Stalin Selvaraj   +1 more
doaj   +1 more source

Protease activity of extracellular enzyme produced by B. subtilis isolated from soil [PDF]

, 2017
Background: Proteases produced by enzymatic method are more environments friendly than chemical process, and they have tremendous potential in the leather industry and in other several industries.
Ahamad, T. (Tasnim), alam, M. G. (Md), Alam, M. S. (Mohammad), Hossain, M. J. (Md), Islam, M. S. (Md), Karim, M. R. (Mohammad), Mahmood, M. S. (Mohammad), Maitra, P. (Pulak), Nazmuzzaman, M. (Md), Rahman, S. (Sezanur), uddin, M. E. (Md)   +10 more
core   +1 more source