Results 111 to 120 of about 316,818 (267)

Biofilm‐Binding Phages Enhance Biofilm Eradication by Synergistic Photothermal and Photodynamic Therapy

Advanced Science, EarlyView.
Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao, Tao Yang, Rui Wang, Hui‐Da Li, Xiao‐Yu Zhang, Feng Cheng, Ying Liu, Jian‐Hua Wang, Ting Yang, Chuanbin Mao   +9 more
wiley   +1 more source

Prokaryotic defense systems: Diversity and evolutionary adaptation

mLife
Bacteriophages and archaeal viruses are the most abundant biological entities on Earth. Through a long‐standing co‐evolutionary arms race, they have driven the emergence of a diverse repertoire of prokaryotic defense systems. This review summarizes these
Changjialian Yang, Luyao Gong, Jing Guo, Hua Xiang   +3 more
doaj   +1 more source

Integrative analysis of fungal communities in three types of Baijiu Daqu using third-generation sequencing and culturomics

Frontiers in Microbiology
Daqu, the core fermentation starter for Chinese Baijiu, harbors intricate and functionally important fungal communities. To comprehensively characterize its biodiversity, we employed an integrated approach combining third-generation amplicon sequencing ...
Yu-Hua Wei, Yu-Hua Wei, Da-Yong Han, Liang Song, Liang-Chen Guo, Liang-Chen Guo, Mei Bai, Mei Bai, Pei-Jie Han, Hai-Yan Zhu, Zhang Wen, Zhang Wen   +11 more
doaj   +1 more source

RNAi in the Rhizarian Phytopathogen Plasmodiophora brassicae: The Causal Agent of Clubroot Disease in Cruciferous Crops

Advanced Science, EarlyView.
This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang, Yupo Wu, Jiachang Hou, Lixia Gao, Longqi Pan, Cuicui Shen, Chuanji Zhao, Feng Gao, Yi Zhang, Li Ren, Xiaoping Fang, Xiaoling Dun, Shengyi Liu, Lijiang Liu   +13 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Identification of targets for high penicillin G production in an industrial strain of Penicillium rubens

Applied Microbiology and Biotechnology
To elucidate the mechanisms underlying high penicillin G (PenG) production, transcriptomic analysis was conducted on 36 samples from the reference Penicillium rubens Wisconsin 54-1255 and its industrial descendant strain IMP002. The resulting dataset was
Kaiqi Dou, Yuanyuan Pan, Yongpeng Yao, Xiuyun Tian, Ning Guo, Gang Liu   +5 more
doaj   +1 more source

BA-ARAP-NMA: A Local Geometry Control Nonlinear Normal-Mode Analysis Method

Biology
Low-frequency normal-mode analysis (NMA) is widely used to predict collective protein motions, but direct Cartesian scaling progressively distorts the alpha-carbon (Cα) backbone as the amplitude increases. We present backbone-angle-compatible as-rigid-as-
Zhenyu Zhang, Dejian Liu, Haiying Yu, Luyan Z. Ma   +3 more
doaj   +1 more source

Microbial diversity and microbial activity in the rhizosphere

Ciencia del Suelo, 2007
It is well established that microbial life only occupies a minor volume of soil being localised in hot spots such as the rhizosphere soil (Nannipieri et al., 2003), where microflora has a continuous access to a flow of low and high molecular weight organic substrates derived from roots.
Nannipieri P., Ascher J., Ceccherini M. T., Landi L., Pietramellara G., Renella G., Valori F.   +6 more
openaire   +3 more sources

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Position Effect Variegation of Penicillium rubens Genome and Application in Heterologous Production of the Plant‐Derived Anthraquinone Physcion

Microbial Biotechnology
The filamentous fungus Penicillium rubens is well known as an industrial host for producing penicillin and also used as a promising chassis for secondary metabolite biosynthesis.
Meng Wu, Yushi Fu, Linqin Tang, Yongpeng Yao, Yuanyuan Pan, Gang Liu   +5 more
doaj   +1 more source