Results 121 to 130 of about 753,950 (380)

Assessment of degree of risk from sources of microbial contamination in cleanrooms; 2: surfaces and liquids [PDF]

open access: yes, 2015
The degree of risk from microbial contamination of manufactured products in healthcare cleanrooms has been assessed in a series of three articles. The first article discussed airborne sources, and this second article considers surface contact and ...
Eaton, T., Whyte, W.
core  

Statistical methods for automated drug susceptibility testing: Bayesian minimum inhibitory concentration prediction from growth curves [PDF]

open access: yes, 2008
Determination of the minimum inhibitory concentration (MIC) of a drug that prevents microbial growth is an important step for managing patients with infections.
Clyde, Merlise A.   +7 more
core   +3 more sources

Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo   +3 more
wiley   +1 more source

Bacterial Biofilm and its Clinical Implications [PDF]

open access: yes, 2018
Microbial biofilm created huge burden in treatment of both community and hospital infections. A biofilm is complex communities of bacteria attached to a surface or interface enclosed in an exopolysaccharide matrix and protected from unfavorable ...
Shakibaie, Prof
core  

Transforming Cancer Diagnosis and Therapy Through Fluorescent Hydrogels: A Review

open access: yesAdvanced Healthcare Materials, EarlyView.
This article reviews fluorescent hydrogel systems for cancer detection, monitoring, and therapy. Mimicking the tumor microenvironment, these hydrogels enable real‐time imaging and targeted drug delivery. The review discusses design strategies, labeling techniques, and applications, highlighting challenges and future opportunities in cancer diagnostics ...
Elahe Masaeli   +2 more
wiley   +1 more source

Caracterización de aislamientos de Pseudomonas aeruginosa productores de carbapenemasas de siete departamentos de Colombia

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2014
Introducción. Pseudomonas aeruginosa es un patógeno oportunista causante de múltiples infecciones en pacientes hospitalizados. Este microorganismo desarrolla fácilmente resistencia a diversos antimicrobianos, incluidos los carbapenémicos, considerados ...
Sandra Yamile Saavedra   +3 more
doaj   +1 more source

Macrobiota — helminths as active participants and partners of the microbiota in host intestinal homeostasis [PDF]

open access: yes, 2016
Important insights have recently been gained in our understanding of the intricate relationship in the intestinal milieu between the vertebrate host mucosal immune response, commensal bacteria, and helminths. Helminths are metazoan worms (macrobiota) and
Gause, William C., Maizels, Rick M.
core   +1 more source

Candida albicans biofilm–induced vesicles confer drug resistance through matrix biogenesis

open access: yesPLoS Biology, 2018
Cells from all kingdoms of life produce extracellular vesicles (EVs). Their cargo is protected from the environment by the surrounding lipid bilayer. EVs from many organisms have been shown to function in cell–cell communication, relaying signals that ...
R. Zarnowski   +10 more
semanticscholar   +1 more source

Metronidazole‐Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis

open access: yesAdvanced Healthcare Materials, EarlyView.
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji   +8 more
wiley   +1 more source

Clinical Trial Findings and Drug Development Challenges for Curcumin in Infectious Disease Prevention and Treatment

open access: yesLife
Since ancient times, turmeric, scientifically known as Curcuma longa, has been renowned for its therapeutic properties. Recently, extensive documentation has highlighted the prevalence of microbial diseases without effective treatments, the increased ...
Mohamed El Oirdi, Mohd Farhan
doaj   +1 more source

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