Results 131 to 140 of about 190,830 (306)

Novel Antifungal Scaffold Targeting Tubulin Overcomes Sclerotinia Sclerotiorum Resistance

Advanced Science, EarlyView.
Addressing pesticide resistance, novel chromone‐acylhydrazone hybrids targeting fungal tubulin are synthesized. Compound G24 potently inhibited S. sclerotiorum (EC50 = 0.21µg mL−1) and demonstrated enhanced field performance via microencapsulation, offering a sustainable strategy against resistance and for global food security.
Lihui Shao, Xianqun Hu, Ying Wu, Xiang Zhou, Bo Zhang, Song Yang   +5 more
wiley   +1 more source

Nanomedicine Strategies Against Biofilm-Associated Infections: Advances, Challenges, and Translational Barriers. [PDF]

Microbiologyopen
Farah H, Kadhim-Abosaoda M, Mohaisen-Mousa H, Renuka Jyothi S, Priyadarshini-Nayak P, Bethanney Janney J, Singh G, Singh-Chauhan A, Kumar-Mishra M.   +8 more
europepmc   +1 more source

Curbing anti-microbial resistance of synthetic medicinal agents using herbal drug alternatives: current trends and future insights

Rabia Bushra, Farah Saeed, Zaheer Ahmed, Sabahat Naeem, Javeria Ishaq, S. Saleem   +5 more
openalex   +2 more sources

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

Assessment of physicians’ perception about antibiotic use and resistance and factors influencing antibiotic prescribing: a situational analysis from Pakistan

Family Medicine & Primary Care Review, 2019
Zikria Saleem, Mohamed Azmi Hassali, Furqan Hashmi, Faiza Azhar, Hamna Hasan, Saba Zaheer, Inaam Ur Rehman   +6 more
doaj   +1 more source

Resistência antimicrobiana de coliformes isolados de leite humano ordenhado

Cadernos de Saúde Pública
A veiculação de microrganismos potencialmente patogênicos, resistentes aos antibióticos, por meio de leite humano ordenhado, pode ser um fator de risco potencial.
Franz Reis Novak, João Aprígio Guerra de Almeida, Marise Dutra Asensi, Bianca Aguiar de Moraes, Dália dos Prazeres Rodrigues   +4 more
doaj  

Water Quality of River Narmada at Gwari Ghat Jabalpur (M.P., India) in Terms of Microbial Load, Drug Resistance and Potability

, 2018
Poornima Sharma
openalex   +2 more sources

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Age- and diet-driven assembly of the gut antibiotic resistome in humans and food-producing animals. [PDF]

Gut Microbes
Zhang T, Wang J, Feng Q, Xu X, Zhu W, Mao S, Liu J.   +6 more
europepmc   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source