Results 171 to 180 of about 717,320 (332)

STING COPII ER Export Trafficking and Signaling Primed by Phosphorylation Switches

Advanced Science, EarlyView.
This schematic outlines STING trafficking and signaling via coat protein II (COPII)‐mediated endoplasmic reticulum (ER) export. Following cyclic GMP‐AMP (cGAMP) stimulation, TANK‐binding kinase 1 (TBK1) activates on COPII vesicles, partially dissociating into the cytosol to phosphorylate ER‐localized STING, creating pSGME/pFS COPII‐sorting motifs ...
Yanan Nan, Dongxiao Cui, Jiajian Guo, Xiaojing Ma, Jiaming Wang, Linyue Guo, Tianyu Li, Mingrui Yang, Guangrui Huang, Anlong Xu, Wenfu Ma   +10 more
wiley   +1 more source

Microbial prevalence and understanding of their antimicrobial susceptibility in urinary tract of patients attending at shar teaching hospital (2018-2022). [PDF]

BMC Res Notes
Mohammed OA, Abubakr KT, Yaghoobi A, Khdhir HH, Ali DH, Abdalrahman PK, Ali BM, Hamarashid SH.   +7 more
europepmc   +1 more source

Blunted blades: new CRISPR-derived technologies to dissect microbial multi-drug resistance and biofilm formation

Christopher Gager, Ana L. Flores‐Mireles   +1 more
openalex   +1 more source

A Novel nor@DHB Matrix for Direct Microbial Analysis in Lung Cancer Tissues

Advanced Science, EarlyView.
Integrated matrix‐assisted laser desorption/ionization mass spectrometry workflow quantifies intratumoral microbes in lung cancer through lipopolysaccharide/lipid A extraction from biopsies. The novel ionic matrix called norharmane conjugated to 2,5‐dihydroxybenzoic acid enhances lipid A ionization, enabling direct detection of bacterial genera ...
Liang Shan, Xin Xu, Lin Huang, Dan Li, Yiran Deng, Xiangfei Xue, Susu Guo, Yiman Huang, Xiao Zhang, Yongchun Yu, Lifang Ma, Kun Qian, Jiayi Wang   +12 more
wiley   +1 more source

L-Asparagine Mediation: A New Initiative to Breaking the Microbial Drug Resistance

Sagnik Majumdar, Anwesha Dutta Chaudhuri, Bhaskar Narayan Chaudhuri, Partha Guchhait, Satadal Das   +4 more
openalex   +1 more source

BCG‐Derived Outer Membrane Vesicles Induce TLR2‐Dependent Trained Immunity to Protect Against Polymicrobial Sepsis

Advanced Science, EarlyView.
B‐OMVs, nanoscale vesicles derived from BCG, are identified as effective and safe inducers of trained immunity that protect against sepsis. Through TLR2‐mediated metabolic and epigenetic reprogramming of hematopoietic stem cells, B‐OMVs enhance inflammatory response and phagocytic activity.
Yuan Gong, Wenyan Hao, Lingqi Xu, Yingyi Yang, Zhenzhen Dong, Peng Pan, Zhenjiang Bai, Jie Huang, Kaidi Yang, Zhu Jin, Rui Kang, Qiang Shan, Jiang huai Wang, Zijian Zhou, Daolin Tang, Jian Wang, Huiting Zhou   +16 more
wiley   +1 more source

Microbial Etiology, Immunological Evaluation, and Drug-Resistance Spectrum Profile of Bloodstream Infections Among Cancer Patients

Sama Jawad Al-Zuwaini, Lena Fadhil Al-Jibouri, Ali H. Al-Marzoqi, Mohammad Golbashy, Israa Adnan Ibraheam, Marwa Fadhil Alsaffar, Ali Talib Ahmed, Zainab A. Tolaifeh, Zahraa Aqeel Muslim, Mohammed Sabah Otaiwi, Israa Aqeel Mohammed Ali ALcharrakh   +10 more
openalex   +1 more source

Bacterial Foreignization Nanosystem Elicits Multi‐Phenotypic T Cells for Antitumor Immunity

Advanced Science, EarlyView.
In this study, a comprehensive strategy for tumor immunogenicity reshaping is implemented, in which all adjuvanticity, antigenicity, and reactogenicity of tumor cells are highly improved by an engineered bacterial nanosystem through a selective membrane fusion process. The resulting foreignized tumor cells evoke potent innate immune responses, inducing
Wan‐Ru Zhuang, Wen‐Chi Xue, Chao Liang, Pan Liu, Yao Lei, Jiaqi He, Ran Cheng, Weidong Nie, Jianxiong Wang, Jie Tang, Hai‐Yan Xie   +10 more
wiley   +1 more source

Why are there so few pathogens? Ecology and evolution in pathogen emergence. [PDF]

PLoS Biol
Drake JM.
europepmc   +1 more source

Studying microbial resistance to drugs and developing new strategies to combat infections: Review

Mazin Abdulridha Ateyah
openalex   +1 more source