Results 161 to 170 of about 364,307 (307)

Multi‐Targeting Non‐Specific Genome Engineering in Bacteria

Advanced Science, EarlyView.
In this study, we provide the first case to use the multi‐targeting integrase (MTI) systems in bacteria and develop a host‐independent generalizable approach, MNGE (Multi‐targeting Non‐specific Genome Engineering), for multi‐copy and random integration of metabolic genes or pathways in both Gram‐positive and Gram‐negative bacteria, which will ...
Runze Sun, Ruixiang You, Yiwen Zhou, Huiyan He, Wenfang Wang, Xudong Qu, Yinhua Lu, Lei Li   +7 more
wiley   +1 more source

Assessment of physicians’ perception about antibiotic use and resistance and factors influencing antibiotic prescribing: a situational analysis from Pakistan

Family Medicine & Primary Care Review, 2019
Zikria Saleem, Mohamed Azmi Hassali, Furqan Hashmi, Faiza Azhar, Hamna Hasan, Saba Zaheer, Inaam Ur Rehman   +6 more
doaj   +1 more source

Vitamin Deficiency or Insufficiency Hypothesis: A Global Health Crisis of Biological Influence Towards Development of Antimicrobial Resistant Strains. A Perspective View. [PDF]

Health Sci Rep
Mashauri HL.
europepmc   +1 more source

Loss of VMP1 Impairs Tight Junction Recycling and Aggravates Intestinal Barrier Dysfunction in Inflammatory Bowel Disease

Advanced Science, EarlyView.
This study identifies vacuole membrane protein 1 (VMP1) as a critical regulator of intestinal epithelial barrier homeostasis. VMP1 facilitates the recruitment of CORO1C to late endosomes, supporting Retromer‐mediated recycling of the tight junction protein Occludin.
Jiawei Zhao, Jianjun Zou, Chen Zhou, Yingui Wang, Yiman Liu, Yanqing Zhou, Yuxiang Wang, Xinyu Zhang, Huishu Yang, Hongjie Yin, Dongsheng Bai, Yue Zhao, Na Lu   +12 more
wiley   +1 more source

From Polyphenols to β-Lactamases: Multitarget Strategies to Defeat Severe Resistance. [PDF]

Int J Mol Sci
Nappa M, Santoro E, Manente R, Cianciulli A, Moccia G, De Caro F, Capunzo M, Boccia G.   +7 more
europepmc   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

Antimicrobial nanomaterials at the nanoscale: design principles, mechanisms, and global challenges. [PDF]

Nanoscale Adv
Senanayake D, Munaweera I.
europepmc   +1 more source

Living Hydrogels: Harnessing Microorganism–Material Synergy for Next‐Generation Therapeutics

Advanced Science, EarlyView.
 . ABSTRACT Microorganism‐based therapies, particularly those utilizing probiotics, have emerged as a powerful biomedical strategy owing to their inherent living functionalities. These living systems can dynamically interact with host environments and self‐regulate their activity, offering superior adaptability, prolonged functionality, and ...
Shuifang Mao, Bingyao Bai, Xingqian Ye, Yiliang Lin   +3 more
wiley   +1 more source

Resistência antimicrobiana de coliformes isolados de leite humano ordenhado

Cadernos de Saúde Pública
A veiculação de microrganismos potencialmente patogênicos, resistentes aos antibióticos, por meio de leite humano ordenhado, pode ser um fator de risco potencial.
Franz Reis Novak, João Aprígio Guerra de Almeida, Marise Dutra Asensi, Bianca Aguiar de Moraes, Dália dos Prazeres Rodrigues   +4 more
doaj  

Microbial diversity, functional genomics and antibiotic resistance in integrated chicken and fish farming systems of Bangladesh. [PDF]

PLoS One
Kador SM, Shila JF, Afrin S, Jannat J, Islam KT, Rubaiyat RN, Bhuiyan MIU, Chakrovarty T, Hasan MS, Sakib N, Rahman MS, Islam OK, Islam MT.   +12 more
europepmc   +1 more source