Laboratory user guide for U.S. public health laboratories : molecular detection of drug resistance (MDDR) in Mycobacterium tuberculosis complex by DNA sequencing (CDC-002-00716) [PDF]
The ability to detect drug resistance rapidly and accurately in Mycobacterium tuberculosis Complex (MTBC) is critical for the effective treatment of patients suffering from tuberculosis (TB) and relevant interventions of TB control programs.
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Systematic characterization of the liver‐resident microbiota in advanced metabolic dysfunction‐associated steatotic liver disease (MASLD) reveals a consistent depletion of Bacteroides uniformis (B. uniformis) in both hepatic and gut microbial communities. Oral gavage of B.
Haiyang Liu +4 more
wiley +1 more source
Therapeutic ecology of the fiber-microbiota-barrier axis in leukemia: resilience, immune recovery and pharmacomicrobiomics. [PDF]
Xie R, Jing X.
europepmc +1 more source
Unveiling the Taxonomic Diversity and Unprecedented Biosynthetic Treasure of the Phylum Myxococcota
Natural products remain vital sources of therapeutics, and the phylum Myxococcota constitutes an especially rich reservoir for them. Based on decades of microbiological efforts, we present 154 new Myxococcota genomes and revise taxonomy quadrupling the number of families and genera.
Amay Ajaykumar Agrawal +25 more
wiley +1 more source
Nanotechnology-Driven Strategies to Combat Antimicrobial Resistance in the One Health Era. [PDF]
Al-Shaebi Z, Akdeniz M, Aydin O.
europepmc +1 more source
Liquid atmospheric pressure matrix‐assisted laser desorption/ionization (LAP‐MALDI) mass spectrometry (MS) provides multiplexed biotyping of microbial cultures using a fast and simple workflow. This is demonstrated for clinically relevant bacteria, resulting in accurate antimicrobial resistance (AMR) detection, speciation by MS/MS sequencing and ...
Lily R. Adair +3 more
wiley +1 more source
Beyond antibiotics: artificial intelligence-enabled anti-infective ecosystems for next-generation precision therapeutics against antimicrobial resistance. [PDF]
Pattapulavar V +3 more
europepmc +1 more source
The Contribution of Class 1 Integron to Antimicrobial Resistance in Stenotrophomonas maltophilia
[[abstract]]Two hundred clinical isolates of Stenotrophomonas maltophilia were examined for the presence of class 1 integron and for the susceptibility to 12 different antimicrobials and detergents. The prevalence of class 1 integron in S.
胡若梅;Rouh-Mei Hu;Lin YT;Huang HH;Yang TC
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Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang +12 more
wiley +1 more source

