Results 191 to 200 of about 717,320 (332)

CXCR1 Depletion in Ly6C+ cDC2 Alleviates Acute Lung Injury via Modulation of Th17/Treg Balance

open access: yesAdvanced Science, EarlyView.
Pro‐inflammatory Ly6C⁺ cDC2s are identified as key effector cells mediating Cxcr1 signaling, driving the progression of ALI. Ly6C⁺ cDC2s release high levels of Il‐6 and Il‐1β, inducing Th17 differentiation. Cxcr1 deficiency reduces Il‐6 and Il‐1β production from Ly6C⁺ cDC2s through suppressing MEK1/ERK /NF‐κB signaling, thereby shifts naïve T cells ...
Shenghui Li   +8 more
wiley   +1 more source

Topographical Patterning of Cell‐Repellent Interfaces for Immune‐Stealth Implantable Electronics via Multiphoton Ablation Lithography

open access: yesAdvanced Science, EarlyView.
Immune‐stealth implantable electronics are developed using cell‐repellent interfaces created by multiphoton ablation lithography, which is the first research applying topographical cues on electronic devices. Laser‐patterned micro‐grooves and nano‐islands on ultrathin films can reduce immune cell adhesion to as low as 5%.
Hyunseon Seo   +16 more
wiley   +1 more source

Volumetric Engineered 3D Drug Reservoir Against Diabetic Implant Infection via Cuproptosis‐Like Bacterial Death and Hunger‐Triggered Maintenance of Mitochondrial Integrity

open access: yesAdvanced Science, EarlyView.
This study provides a volumetric engineered 3D drug reservoir to combat diabetic implant infection. Cu‐doped quantum dots induce cuproptosis‐like bacterial death via metabolic collapse, while glucose oxidase triggers hunger‐triggered mitochondrial protection in host cells.
Dize Li   +8 more
wiley   +1 more source

The impact of florfenicol treatment on the microbial populations present in the gill, intestine, and skin of channel catfish (Ictalurus punctatus). [PDF]

open access: yesAnim Microbiome
Wang H   +12 more
europepmc   +1 more source

Recent Advances of Microcapsule‐based Intelligent Coatings: From Bioinspired Designs, Material Selections, to Potential Applications

open access: yesAdvanced Science, EarlyView.
Microcapsule‐based intelligent coatings (MICs) have shown great potential in the fields of biomedicine, smart buildings, marine protection, and aerospace. However, they currently face challenges in the integration of coating functions and applications in complex systems.
Yue Zhao   +5 more
wiley   +1 more source

Akkermansia muciniphila‐Derived N‐Acetylspermidine Modulates the Localization of Intestinal α1,2‐Fucosylated Proteins to Maintain Gut Homeostasis

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Akkermansia muciniphila alleviates colitis by enhancing intestinal α1,2‐fucosylation through its metabolite N‐acetylspermidine. Mechanistically, N‐acetylspermidine‐induced PIM1 inhibition promotes HDAC2‐mediated reduction of chromatin accessibility at TP73, thereby upregulating C1GALT1C1 to boost α1,2‐fucosylation.
Ye Yao   +10 more
wiley   +1 more source

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