Results 81 to 90 of about 4,768,016 (302)

Drug resistance [PDF]

Part of series 1 of the CDC Museum set of Infectious disease trading cards, featuring photos and information about some of the infectious diseases that CDC studies.Drug resistance happens when antimicrobial drugs\u2013some of which are called antibiotics\

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Genetically Programmed Shape‐Morphing of Engineered Living Materials

Advanced Functional Materials, EarlyView.
Here, bacterial and mammalian engineered living materials (ELMs) are presented, in which living cells direct genetically programmed and enzymatically mediated shape‐morphing. The resulting deformation and shape‐recovery can be actuated in a genetically controlled manner by an ELM incorporating out‐of‐equilibrium counteracting biochemical reactions with
Jan Becker, Yuchen Liu, Miguel Baños, Rosanne Schmachtenberg, Mahmudul Hasan, Claudia Fink‐Straube, Luai R. Khoury, Wilfried Weber   +7 more
wiley   +1 more source

CHANGE IN THE CARBAPENEM RESISTANCE PROFILE AND PRESENTATION OF RESISTANCE PHENOTYPES IN KLEBSIELLA PNEUMONIAE: ANALYSIS OF BLOOD CULTURES FROM A PRIVATE TERTIARY HOSPITAL IN PORTO ALEGRE BETWEEN 2014 AND 2024

Brazilian Journal of Infectious Diseases
Introduction/Objective: In the face of increasing antimicrobial resistance, in 2017 the World Health Organization listed priority bacteria for prevention and treatment.
Emerson dos Santos Hoffmann, Amanda de Farias Balbinot, Nadiana Inocente, Rodrigo Chiavaro da Fonseca, Jaysa Pizzi, Gabriela Pereira Flores, Cristiane Tejada da Silva Kawski, Muriel Gorges, Guilherme Geraldo Lovato Sório, Alexandre Prehn Zavascki, Beatriz Arns   +10 more
doaj   +1 more source

Protein‐Polymer Dynamic Hydrogels Utilizing Native Ligand Binding for Injectable Therapeutic Delivery and 3D Printing

Advanced Healthcare Materials, EarlyView.
Dynamic nanocolloidal hydrogels were synthesized via the co‐assembly of ligand‐modified spheroidal hyperbranched poly(glycerol) (HPG) and soluble albumin nanoparticles (SANs). Co‐assembly occurred through self‐association of the HPG, as well as its interaction with SANs via native ligand binding.
S. Cem Millik, Yonghui Wang, Kefan Song, Jessica M. Snyder, LeAnn Le, Lauren G. Brown, Shanny Hsuan Kuo, Ashleigh B. Theberge, Suzie H. Pun, Alshakim Nelson   +9 more
wiley   +1 more source

A Public health action plan to combat antimicrobial resistance [PDF]

In 2001, the Task Force developed an initial Action Plan, outlining specific issues, goals, and actions important for addressing the problem of AR. This document, entitled A Public Health Action Plan to Combat Antimicrobial Resistance, Part I: Domestic ...

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Early Detection of Antibiotic Resistance in Positive Blood Cultures: A Study from a Tertiary Care Center in India [PDF]

Medical Laboratory Journal, 2023
Background and objectives: Conventional culture and sensitivity methods take around 48 hours to generate antibiotic sensitivity results after a blood culture is flagged as positive by automated systems.
Sadaf Khursheed Baba, Abiroo Jan, Mohd Suhail lone, Dalip k kakru, Bashir Ahmad Fomda, Gulnaz Bashir, Nadeem ahmad bhat   +6 more
doaj  

Evolution of antibiotic resistance at non-lethal drug concentrations

, 2012
Human use of antimicrobials in the clinic, community and agricultural systems has driven selection for resistance in bacteria. Resistance can be selected at antibiotic concentrations that are either lethal or non-lethal, and here we argue that selection ...
Andersson, Dan I,, Hughes, Diarmaid,
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Modelling the impact of intermittent preventive treatment for malaria on selection pressure for drug resistance. [PDF]

, 2007
BACKGROUND\ud \ud Intermittent preventive treatment (IPT) is a promising intervention for malaria control, although there are concerns about its impact on drug resistance.\ud \ud METHODS\ud \ud The key model inputs are age-specific values for a) baseline
Sutherland Colin, Schellenberg, David, Roper, C., Schellenberg, D., Roper Cally, Roper, Cally, Sutherland, C., Cissé, Badara, Alexander, N., Alexander Neal, Sutherland, Colin, Schellenberg David, Cissé Badara, Alexander, Neal, Neal Alexander, Colin Sutherland, Cally Roper, David Schellenberg, Badara Cissé   +18 more
core   +1 more source

Hybrid Biofabrication of a Hierarchically Organized Periosteum‐Inspired In Vitro Platform

Advanced Healthcare Materials, EarlyView.
A hybrid biofabrication strategy integrates melt electrowriting with extrusion‐based 3D bioprinting to create a hierarchically organized periosteum‐inspired in vitro platform. Spatially defined osteogenic, fibrous, and endothelial cell‐containing compartments support long‐term culture, osteogenic maturation, and CD31+ endothelial cell organization ...
Yakui Liu, Xinggui Tian, Anne Bernhardt, Anja Lode, Max von Witzleben, Ege Kirbas, Stefan Zwingenberger, Michael Gelinsky   +7 more
wiley   +1 more source

Enhanced diagnosis of multi-drug-resistant microbes using group association modeling and machine learning

Nature Communications
New solutions are needed to detect genotype-phenotype associations involved in microbial drug resistance. Herein, we describe a Group Association Model (GAM) that accurately identifies genetic variants linked to drug resistance and mitigates false ...
Julian G. Saliba, Wenshu Zheng, Qingbo Shu, Liqiang Li, Chi Wu, Yi Xie, Christopher J. Lyon, Jiuxin Qu, Hairong Huang, Binwu Ying, Tony Ye Hu   +10 more
doaj   +1 more source