Results 81 to 90 of about 1,151,409 (309)

Building Infectious Disease Research Programs to Promote Security and Enhance Collaborations with Countries of the Former Soviet Union

Frontiers in Public Health, 2015
Addressing the threat of infectious diseases, whether natural, the results of a laboratory accident, or a deliberate act of bioterrorism, requires no corner of the world be ignored. The mobility of infectious agents and their rapid adaptability, whether
James C Bartholomew, Andrew David Pearson, Nils Chr. Stenseth, James W LeDuc, David L. eHirschberg, Rita R Colwell   +5 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

From Recharge, to Groundwater, to Discharge Areas in Aquifer Systems in Quebec (Canada): Shaping of Microbial Diversity and Community Structure by Environmental Factors

, 2022
Groundwater recharge and discharge rates and zones are important hydrogeological characteristics of aquifer systems, yet their impact on the formation of both subterranean and surface microbiomes remains largely unknown.
Karine Villeneuve, Michel Violette, Cassandre Sara Lazar   +2 more
core   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Genes involucrados en la biogénesis de fimbrias afectan la formación de biopelículas por parte de Klebsiella pneumoniae

Biomédica: revista del Instituto Nacional de Salud, 2006
Introducción. Klebsiella pneumoniae es un patógeno oportunista comúnmente asociado con infecciones hospitalarias. La persistencia y patogénesis de este microorganismo pueden estar asociadas con su capacidad para formar biopelículas.
Ana Victoria Suescún, Juan Rodrigo Cubillos, María Mercedes Zambrano   +2 more
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Advances in Diversity, Evolutionary Dynamics and Biotechnological Potential of Restriction-Modification Systems

Microorganisms
Restriction–modification systems (RMS) are ubiquitous in prokaryotes and serve as primitive immune-like mechanisms that safeguard microbial genomes against foreign genetic elements.
Chen Chen, Yue Zhang, Hao Wu, Jianjun Qiao, Qinggele Caiyin   +4 more
doaj   +1 more source

cual-id: Globally Unique, Correctable, and Human-Friendly Sample Identifiers for Comparative Omics Studies

mSystems, 2016
The number of samples in high-throughput comparative “omics” studies is increasing rapidly due to declining experimental costs. To keep sample data and metadata manageable and to ensure the integrity of scientific results as the scale of these projects ...
John H. Chase, Evan Bolyen, Jai Ram Rideout, J. Gregory Caporaso   +3 more
doaj   +1 more source

A culture-independent approach to unravel uncultured bacteria and functional genes in a complex microbial community [PDF]

, 2012
Most microorganisms in nature are uncultured with unknown functionality. Sequence-based metagenomics alone answers 'who/what are there?' but not 'what are they doing and who is doing it and how?'.
Zhou, Q., Kalin, Robert M, Xu, Jian, Wang Yun, Huang, Wei E, Stephen Rolfe, Huang Wei E., Rolfe, Stephen A., Rolfe Stephen, Kang Ning, Huang Shi, Kalin, Robert M., Kalin, R.M., Robert M Kalin, Kalin Robert M., Xu, J., Huang, Shi, Yin Chen, Xu Jian, Shi Huang, Chen Yin, Chen, Y., Huang, S., Jian Xu (31545), Ning, Kang, Wei E. Huang (125868), Yin Chen (125855), Rolfe, Stephen, Yun Wang (32846), Qian Zhou, Jian Xu, Wei E Huang, Yun Wang, Ning, K., Chen, Yin, Zhou, Qian, Huang, W.E., Huang, Wei E., Stephen Rolfe (125866), Ning Kang, Shi Huang (125861), Wang, Yun, Wang, Y., Rolfe, S., Zhou Qian, Kang Ning (59789), Robert M. Kalin (125864), Qian Zhou (125859)   +47 more
core   +2 more sources

Unravelling Metagenomics Approach for Microbial Biofuel Production

, 2022
Renewable biofuels, such as biodiesel, bioethanol, and biobutanol, serve as long-term solutions to fossil fuel depletion. A sustainable approach feedstock for their production is plant biomass, which is degraded to sugars with the aid of microbes-derived
Leonidas Matsakas, Patel, Alok,, Alok Patel, Prasad, Ramasare, Km Sartaj, Matsakas, Leonidas,, Patel, Alok, Sartaj, Km,, Ramasare Prasad, Sartaj, Km, Matsakas, Leonidas, Prasad, Ramasare,   +11 more
core   +1 more source