Results 131 to 140 of about 862,177 (279)

Microbial Genomics as a Catalyst for Targeted Antivirulence Therapeutics. [PDF]

Front Med (Lausanne), 2021
Sintchenko V, Timms V, Sim E, Rockett R, Bachmann N, O'Sullivan M, Marais B.   +6 more
europepmc   +1 more source

Genome wide identification of genes that play a role in boron stress response in yeast

, 2011
Genomics 97 (2011) 106–111.Boron is an essential micronutrient for plants and it is either necessary or beneficial for animals. Studies identified only few genes related to boron metabolism thus far and details of how boron is imported into cells and ...
Uluışık, İrem, Kaya, Alaattin, Karakaya, Hüseyin Çağlar, Avşar, Kadir   +3 more
core   +1 more source

Single‐Cell Transcriptomics and Metabolomics Reveal Glutamate Dehydrogenase as a Central Regulator of Nitrogen Metabolic Remodeling During Alkalinity Adaptation in Crustaceans

Advanced Science, EarlyView.
Single‐cell transcriptomics reveals the cellular response of Macrobrachium hainanense to carbonate alkalinity stress. Alkalinity stress impairs branchial ammonia excretion, induces mitochondrial dysfunction, and drives cell‐type‐specific changes in gills and hemocytes.
Yiting Jin, Zhimin Lv, Chao Bian, Qibin Yang, Na Zhou, Jianguang Qin, Shengming Sun   +6 more
wiley   +1 more source

Evolution of Microbial Genomics: Conceptual Shifts over a Quarter Century. [PDF]

Trends Microbiol, 2021
Koonin EV, Makarova KS, Wolf YI.
europepmc   +1 more source

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

Analysis of complete genomes of Mycobacterium tuberculosis sublineage 2.1 (Proto-Beijing) revealed the presence of three pe_pgrs3-pe_pgrs4-like genes

Scientific Reports
Mycobacterium tuberculosis Complex (MTBC), the etiological agent of tuberculosis (TB), demonstrates considerable genotypic diversity with distinct geographic distributions and variable virulence profiles.
Olabisi Flora Davies-Bolorunduro, Bharkbhoom Jaemsai, Wuthiwat Ruangchai, Thanakron Noppanamas, Manon Boonbangyang, Thavin Bodharamik, Waritta Sawaengdee, Surakameth Mahasirimongkol, Prasit Palittapongarnpim   +8 more
doaj   +1 more source

GENOMICS AND CLINICAL MEDICINE

, 2008
Contributors -- Pt. I. General genomics -- 1. From genes to genomes: a historical perspective / Ian Dunham and Don Powell -- 2. The human genome: structure and organization / Andrew Read -- 3. Human functional genomics and proteomics / Yoshiji Yamada,

core  

A Microcapsule‐Integrated smRandom‐seq Platform Enables Fixation‐Free Single Microbe RNA Sequencing

Advanced Science, EarlyView.
We developed a microcapsule‐integrated high‐throughput fixation‐free single‐microbe RNA‐seq workflow in which microbes are encapsulated in aqueous two‐phase microcapsules for physical confinement of nucleic acids. This platform enables co‐encapsulation with barcoded beads for sequencing and reveals that fixation‐free processing enhances transcriptomic ...
Mengdi Song, Yuting Wang, Zhaolun Wang, Shunji Zhang, Zhengmin Tang, Yongcheng Wang   +5 more
wiley   +1 more source

A Customized Monkeypox Virus Genomic Database (MPXV DB v1.0) for Rapid Sequence Analysis and Phylogenomic Discoveries in CLC Microbial Genomics. [PDF]

Viruses, 2022
Shen-Gunther J, Cai H, Wang Y.
europepmc   +1 more source

Australian Microbial Genomics Research Network

Australian Microbial Genomics Research Network. The Australian Microbial Genomics Research Network aims to bring together Australian scientists with complementary expertise in microbial genomics within two ARC Centres, a Ramaciotti Centre and four ...

core